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Network-based models of epidemic spread have become increasingly popular in recent decades. Despite a rich foundation of such models, few low-dimensional systems for modeling SIS-type diseases have been proposed that manage to capture the…

Dynamical Systems · Mathematics 2021-01-01 Carl Corcoran , Alan Hastings

Chemical reaction networks (CRNs) provide a convenient language for modelling a broad variety of biological systems. These models are commonly studied with respect to the time series they generate in deterministic or stochastic simulations.…

Molecular Networks · Quantitative Biology 2019-07-11 Ozan Kahramanoğulları

Dynamical systems arising from chemical reaction networks with mass action kinetics are the subject of chemical reaction network theory (CRNT). In particular, this theory provides statements about uniqueness, existence, and stability of…

Dynamical Systems · Mathematics 2014-06-26 Stefan Müller , Georg Regensburger

We consider local bifurcations of equilibria in dynamical systems arising from chemical reaction networks with mass action kinetics. In particular, given any mass action network admitting a local bifurcation of equilibria, assuming only a…

Dynamical Systems · Mathematics 2025-05-20 Murad Banaji , Balázs Boros , Josef Hofbauer

Both natural and synthetic chemical systems not only exhibit a range of non-trivial dynamics, but also transition between qualitatively different dynamical behaviours as environmental parameters change. Such transitions are called…

Molecular Networks · Quantitative Biology 2026-02-03 Alexander Dack , Tomislav Plesa , Thomas E. Ouldridge

We analyze a family of clustered excitatory-inhibitory neural networks and the underlying bifurcation structures that arise because of permutation symmetries in the network as the global coupling strength $g$ is varied. We primarily…

Chaotic Dynamics · Physics 2022-12-09 Ross Parker , Andrea K. Barreiro

The popularity of molecular computation has given rise to several models of abstraction, one of the more recent ones being Chemical Reaction Networks (CRNs). These are equivalent to other popular computational models, such as Vector…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-02-28 Robert M. Alaniz , Bin Fu , Timothy Gomez , Elise Grizzell , Andrew Rodriguez , Marco Rodriguez , Robert Schweller , Tim Wylie

This paper is a computational bifurcation analysis of a non-linear partial differential equation (PDE) characterizing equilibrium configurations in Micro electromechanical Systems (MEMS). MEMS are engineering systems that utilize…

Dynamical Systems · Mathematics 2024-01-24 Charles Naudet , Alan E. Lindsay

In epidemiological modelling, dynamics on networks, and in particular adaptive and heterogeneous networks have recently received much interest. Here we present a detailed analysis of a previously proposed model that combines heterogeneity…

Physics and Society · Physics 2016-09-21 Hui Yang , Tim Rogers , Thilo Gross

We study a nonlinear PDE problem motivated by the peculiar patterns arising in myxobacteria, namely counter-migrating cell density waves. We rigorously prove the existence of Hopf bifurcations for some specific values of the parameters of…

Analysis of PDEs · Mathematics 2018-07-25 Narek Hovsepyan , Juan J. L. Velázquez

We study the emergence of symmetric oscillatory behavior in multi-agent systems where each agent incorporates a continuous memory of its past states and past rates of change, modeled by distributed retarded and neutral delays. The…

Dynamical Systems · Mathematics 2026-04-23 Casey Crane

We performed a thorough sensitivity analysis of the herd immunity threshold for discrete-time SIR compartmental models with a static network structure. We find unexpectedly that these models violate classical intuition which holds that the…

Populations and Evolution · Quantitative Biology 2023-02-27 Sinan A. Ozbay , Bjarke F. Nielsen , Maximilian M. Nguyen

Analysis of large continuous-time stochastic systems is a computationally intensive task. In this work we focus on population models arising from chemical reaction networks (CRNs), which play a fundamental role in analysis and design of…

Systems and Control · Computer Science 2019-05-27 Milan Češka , Jan Křetínský

We study the tipping point collective dynamics of an adaptive susceptible-infected-susceptible (SIS) epidemiological network in a data-driven, machine learning-assisted manner. We identify a parameter-dependent effective stochastic…

Machine Learning · Computer Science 2023-11-14 Nikolaos Evangelou , Tianqi Cui , Juan M. Bello-Rivas , Alexei Makeev , Ioannis G. Kevrekidis

An adaptive network model using SIS epidemic propagation with link-type dependent link activation and deletion is considered. Bifurcation analysis of the pairwise ODE approximation and the network-based stochastic simulation is carried out,…

Probability · Mathematics 2014-10-21 András Szabó-Solticzky , Luc Berthouze , Istvan Z. Kiss , Péter L. Simon

Stochastic thermodynamics gives universal relations for microscopic entropy production, yet its critical behavior at macroscopic nonequilibrium transitions remains unclassified. We study well-mixed reversible chemical reaction networks in…

Statistical Mechanics · Physics 2026-05-06 Kyota Tamano , Keiji Saito

Hopf bifurcation in networks of coupled ODEs creates periodic states in which the relative phases of nodes are well defined near bifurcation. When the network is a fully inhomogeneous nearest-neighbour coupled unidirectional ring, and node…

Dynamical Systems · Mathematics 2024-04-15 Ian Stewart

Modern machine learning models excel at pattern recognition but remain brittle, often failing to generalize out of distribution (OOD) because they capture spurious correlations rather than the underlying causal data-generating process.…

Machine Learning · Computer Science 2026-05-26 Govind Vallabhasseri Binish , Abdhul Ahadh , Rano Roy Kavanal , Arya Ukunde

This paper is concerned with the robustness of the sustained oscillations predicted by an epidemic ODE model defined on contact networks. The model incorporates the spread of awareness among individuals and, moreover, a small inflow of…

Populations and Evolution · Quantitative Biology 2020-11-11 David Juher , David Rojas , Joan Saldaña

The dynamics of many epidemic compartmental models for infectious diseases that spread in a single host population present a second-order phase transition. This transition occurs as a function of the infectivity parameter, from the absence…

Physics and Society · Physics 2023-01-02 Alex Arenas , Antonio Garijo , Sergio Gómez , Jordi Villadelprat