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Capturing voxel-wise spatial correspondence across distinct modalities is crucial for medical image analysis. However, current registration approaches are not practical enough in terms of registration accuracy and clinical applicability. In…

Computer Vision and Pattern Recognition · Computer Science 2025-06-26 Tao Guo , Yinuo Wang , Shihao Shu , Weimin Yuan , Diansheng Chen , Zhouping Tang , Cai Meng , Xiangzhi Bai

Neural electrical activity is fundamental to brain function, underlying a range of cognitive and behavioral processes, including movement, perception, decision-making, and consciousness. Abnormal patterns of neural signaling often indicate…

Neurons and Cognition · Quantitative Biology 2025-09-03 Zhizhang Yuan , Fanqi Shen , Meng Li , Yuguo Yu , Chenhao Tan , Yang Yang

Recent learning-based approaches have made astonishing advances in calibrated medical imaging like computerized tomography (CT), yet they struggle to generalize in uncalibrated modalities -- notably magnetic resonance (MR) imaging, where…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Peirong Liu , Oula Puonti , Xiaoling Hu , Daniel C. Alexander , Juan E. Iglesias

Clinical diagnostic workups typically follow a modality escalation pathway: after initial clinical evaluation, clinicians begin with routine structural imaging (e.g., MRI), selectively add sequences such as FLAIR or T2 to refine the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Guangqian Yang , Tong Ding , Wenlong Hou , Yue Xun , Ye Du , Qian Niu , Shujun Wang

Deformable image registration can obtain dynamic information about images, which is of great significance in medical image analysis. The unsupervised deep learning registration method can quickly achieve high registration accuracy without…

Computer Vision and Pattern Recognition · Computer Science 2022-07-19 Xiao Fan , Shuxin Zhuang , Zhemin Zhuang , Ye Yuan , Shunmin Qiu , Alex Noel Joseph Raj , Yibiao Rong

We describe a diffeomorphic registration algorithm that allows groups of images to be accurately aligned to a common space, which we intend to incorporate into the SPM software. The idea is to perform inference in a probabilistic graphical…

Computer Vision and Pattern Recognition · Computer Science 2021-05-10 Mikael Brudfors , Yaël Balbastre , Guillaume Flandin , Parashkev Nachev , John Ashburner

Magnetic resonance imaging~(MRI) have played a crucial role in brain disease diagnosis, with which a range of computer-aided artificial intelligence methods have been proposed. However, the early explorations usually focus on the limited…

Computer Vision and Pattern Recognition · Computer Science 2023-09-14 Jiayu Lei , Lisong Dai , Haoyun Jiang , Chaoyi Wu , Xiaoman Zhang , Yao Zhang , Jiangchao Yao , Weidi Xie , Yanyong Zhang , Yuehua Li , Ya Zhang , Yanfeng Wang

As large language models (LLMs) continue to revolutionize AI research, there is a growing interest in building large-scale brain foundation models to advance neuroscience. While most existing brain foundation models are pre-trained on…

Neurons and Cognition · Quantitative Biology 2026-02-11 Xinxu Wei , Kanhao Zhao , Yong Jiao , Lifang He , Yu Zhang

We present VoxelMorph, a fast learning-based framework for deformable, pairwise medical image registration. Traditional registration methods optimize an objective function for each pair of images, which can be time-consuming for large…

Computer Vision and Pattern Recognition · Computer Science 2019-09-04 Guha Balakrishnan , Amy Zhao , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

MRI, a widespread non-invasive medical imaging modality, is highly sensitive to patient motion. Despite many attempts over the years, motion correction remains a difficult problem and there is no general method applicable to all situations.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Oscar Dabrowski , Jean-Luc Falcone , Antoine Klauser , Julien Songeon , Michel Kocher , Bastien Chopard , François Lazeyras , Sébastien Courvoisier

Diffeomorphic deformable multi-modal image registration is a challenging task which aims to bring images acquired by different modalities to the same coordinate space and at the same time to preserve the topology and the invertibility of…

Image and Video Processing · Electrical Eng. & Systems 2022-03-16 Vasiliki Sideri-Lampretsa , Georgios Kaissis , Daniel Rueckert

Deformable image registration is a key task in medical image analysis. The Brain Tumor Sequence Registration challenge (BraTS-Reg) aims at establishing correspondences between pre-operative and follow-up scans of the same patient diagnosed…

Image and Video Processing · Electrical Eng. & Systems 2022-12-12 Javid Abderezaei , Aymeric Pionteck , Agamdeep Chopra , Mehmet Kurt

3D structural Magnetic Resonance Imaging (MRI) brain scans are commonly acquired in clinical settings to monitor a wide range of neurological conditions, including neurodegenerative disorders and stroke. While deep learning models have…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Emily Kaczmarek , Justin Szeto , Brennan Nichyporuk , Tal Arbel

Foundation models (FMs), large neural networks pretrained on extensive and diverse datasets, have revolutionized artificial intelligence and shown significant promise in medical imaging by enabling robust performance with limited labeled…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Salah Ghamizi , Georgia Kanli , Yu Deng , Magali Perquin , Olivier Keunen

The widespread use of Magnetic Resonance Imaging (MRI) in combination with deep learning shows promise for many high-impact automated diagnostic and prognostic tools. However, training new models requires large amounts of labeled data, a…

Image and Video Processing · Electrical Eng. & Systems 2025-07-24 Haoyu Dong , Yuwen Chen , Hanxue Gu , Nicholas Konz , Yaqian Chen , Qihang Li , Maciej A. Mazurowski

Many real-world settings require registration of a pair of medical images that differ in spatial resolution, which may arise from differences in image acquisition parameters like pixel spacing, slice thickness, and field-of-view. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Mina C. Moghadam , Alan Q. Wang , Omer Taub , Martin R. Prince , Mert R. Sabuncu

Accurate compensation of brain shift is critical for maintaining the reliability of neuronavigation during neurosurgery. While keypoint-based registration methods offer robustness to large deformations and topological changes, they…

Image and Video Processing · Electrical Eng. & Systems 2026-02-05 Tiago Assis , Ines P. Machado , Benjamin Zwick , Nuno C. Garcia , Reuben Dorent

This paper introduces GeoMorph, a novel geometric deep-learning framework designed for image registration of cortical surfaces. The registration process consists of two main steps. First, independent feature extraction is performed on each…

Machine Learning · Computer Science 2023-11-23 Mohamed A. Suliman , Logan Z. J. Williams , Abdulah Fawaz , Emma C. Robinson

Multimodal learning, especially large-scale multimodal pre-training, has developed rapidly over the past few years and led to the greatest advances in artificial intelligence (AI). Despite its effectiveness, understanding the underlying…

Neural and Evolutionary Computing · Computer Science 2022-08-18 Haoyu Lu , Qiongyi Zhou , Nanyi Fei , Zhiwu Lu , Mingyu Ding , Jingyuan Wen , Changde Du , Xin Zhao , Hao Sun , Huiguang He , Ji-Rong Wen