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Deep unsupervised anomaly detection in brain magnetic resonance imaging offers a promising route to identify pathological deviations without requiring lesion-specific annotations. Yet, fragmented evaluations, heterogeneous datasets, and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Alexander Frotscher , Christian F. Baumgartner , Thomas Wolfers

Segmentation masks of pathological areas are useful in many medical applications, such as brain tumour and stroke management. Moreover, healthy counterfactuals of diseased images can be used to enhance radiologists' training files and to…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Alessandro Fontanella , Grant Mair , Joanna Wardlaw , Emanuele Trucco , Amos Storkey

Tables are an abundant form of data with use cases across all scientific fields. Real-world datasets often contain anomalous samples that can negatively affect downstream analysis. In this work, we only assume access to contaminated data…

Machine Learning · Computer Science 2023-07-25 Guy Zamberg , Moshe Salhov , Ofir Lindenbaum , Amir Averbuch

Automated methods for Alzheimer's disease (AD) classification have the potential for great clinical benefits and may provide insight for combating the disease. Machine learning, and more specifically deep neural networks, have been shown to…

In recent years, anomaly detection has become an essential field in medical image analysis. Most current anomaly detection methods for medical images are based on image reconstruction. In this work, we propose a novel anomaly detection…

Computer Vision and Pattern Recognition · Computer Science 2023-01-20 Florentin Bieder , Julia Wolleb , Robin Sandkühler , Philippe C. Cattin

Anomaly detection is a task that recognizes whether an input sample is included in the distribution of a target normal class or an anomaly class. Conventional generative adversarial network (GAN)-based methods utilize an entire image…

Computer Vision and Pattern Recognition · Computer Science 2021-04-01 Jou Won Song , Kyeongbo Kong , Ye In Park , Suk-Ju Kang

Anomaly detection (AD) in a surveillance scenario is an emerging and challenging field of research. For autonomous vehicles like drones or cars, it is immensely important to distinguish between normal and abnormal states in real-time.…

Computer Vision and Pattern Recognition · Computer Science 2020-07-15 Sayeed Shafayet Chowdhury , Kazi Mejbaul Islam , Rouhan Noor

Early detection of newly emerging diseases, lesion severity assessment, differentiation of medical conditions and automated screening are examples for the wide applicability and importance of anomaly detection (AD) and unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Branko Mitic , Philipp Seeböck , Helmut Prosch , Georg Langs

The primary goal of this work is to study the effectiveness of an unsupervised domain adaptation approach for various applications such as binary classification and anomaly detection in the context of Alzheimer's disease (AD) detection for…

Image and Video Processing · Electrical Eng. & Systems 2022-12-27 Pranath Reddy

Anomaly detection (AD) is a crucial machine learning task that aims to learn patterns from a set of normal training samples to identify abnormal samples in test data. Most existing AD studies assume that the training and test data are drawn…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Tri Cao , Jiawen Zhu , Guansong Pang

Alzheimer's disease (AD), a degenerative brain condition, can benefit from early prediction to slow its progression. As the disease progresses, patients typically undergo brain atrophy. Current prediction methods for Alzheimers disease…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Xin Honga , Jie Lin , Minghui Wang

Reliably modeling normality and differentiating abnormal appearances from normal cases is a very appealing approach for detecting pathologies in medical images. A plethora of such unsupervised anomaly detection approaches has been made in…

Computer Vision and Pattern Recognition · Computer Science 2019-04-19 Christoph Baur , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab

This paper proposed a novel anomaly detection (AD) approach of High-speed Train images based on convolutional neural networks and the Vision Transformer. Different from previous AD works, in which anomalies are identified with a single…

Computer Vision and Pattern Recognition · Computer Science 2022-03-30 Zhixue Wang , Yu Zhang , Lin Luo , Nan Wang

Early diagnosis, playing an important role in preventing progress and treating the Alzheimer\{'}s disease (AD), is based on classification of features extracted from brain images. The features have to accurately capture main AD-related…

Machine Learning · Computer Science 2016-11-15 Ehsan Hosseini-Asl , Robert Keynto , Ayman El-Baz

Anomaly detection in tabular data remains challenging due to complex feature interactions and the scarcity of anomalous examples. Denoising autoencoders rely on fixed-magnitude noise, limiting adaptability to diverse data distributions.…

Machine Learning · Computer Science 2025-08-04 Timur Sattarov , Marco Schreyer , Damian Borth

We present a system for anomaly detection in histopathological images. In histology, normal samples are usually abundant, whereas anomalous (pathological) cases are scarce or not available. Under such settings, one-class classifiers trained…

Computer Vision and Pattern Recognition · Computer Science 2024-01-10 Igor Zingman , Birgit Stierstorfer , Charlotte Lempp , Fabian Heinemann

This study presents an innovative method for Alzheimer's disease diagnosis using 3D MRI designed to enhance the explainability of model decisions. Our approach adopts a soft attention mechanism, enabling 2D CNNs to extract volumetric…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Gabriele Lozupone , Alessandro Bria , Francesco Fontanella , Frederick J. A. Meijer , Claudio De Stefano

Alzheimer's Disease (AD) detection employs machine learning classification models to distinguish between individuals with AD and those without. Different from conventional classification tasks, we identify within-class variation as a…

Audio and Speech Processing · Electrical Eng. & Systems 2025-09-29 Jiawen Kang , Dongrui Han , Lingwei Meng , Jingyan Zhou , Jinchao Li , Xixin Wu , Helen Meng

Supervised deep learning techniques show promise in medical image analysis. However, they require comprehensive annotated data sets, which poses challenges, particularly for rare diseases. Consequently, unsupervised anomaly detection (UAD)…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Finn Behrendt , Debayan Bhattacharya , Lennart Maack , Julia Krüger , Roland Opfer , Robin Mieling , Alexander Schlaefer

Traditional deep learning models often lack annotated data, especially in cross-domain applications such as anomaly detection, which is critical for early disease diagnosis in medicine and defect detection in industry. To address this…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Wahyu Rahmaniar , Kenji Suzuki
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