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We propose to use Twitter data as social-spatial sensors. This study deals with the question whether research papers on certain diseases are perceived by people in regions (worldwide) that are especially concerned by the diseases. Since…

Digital Libraries · Computer Science 2021-01-27 Lutz Bornmann , Robin Haunschild , Vanash M. Patel

Patients' expectations towards their treatment have a substantial effect on the treatments' success. While primarily studied in clinical settings, online patient platforms like medical subreddits may hold complementary insights: treatment…

Computation and Language · Computer Science 2026-02-18 Aswathy Velutharambath , Amelie Wührl

The pervasive influence of social media during the COVID-19 pandemic has been a double-edged sword, enhancing communication while simultaneously propagating misinformation. This \textit{Digital Infodemic} has highlighted the urgent need for…

Computation and Language · Computer Science 2024-12-24 Tanjim Bin Faruk

With the development of web technology, social media texts are becoming a rich source for automatic mental health analysis. As traditional discriminative methods bear the problem of low interpretability, the recent large language models…

Computation and Language · Computer Science 2024-02-14 Kailai Yang , Tianlin Zhang , Ziyan Kuang , Qianqian Xie , Jimin Huang , Sophia Ananiadou

We investigate the role of large language models (LLMs) in supporting mental health by analyzing Reddit posts and comments about mental health conversations with ChatGPT. Our findings reveal that users value ChatGPT as a safe,…

Human-Computer Interaction · Computer Science 2025-10-28 Kyuha Jung , Gyuho Lee , Yuanhui Huang , Yunan Chen

Social biases such as gender or racial biases have been reported in language models (LMs), including Masked Language Models (MLMs). Given that MLMs are continuously trained with increasing amounts of additional data collected over time, an…

Computation and Language · Computer Science 2024-06-21 Yi Zhou , Danushka Bollegala , Jose Camacho-Collados

Large Language Models (LLMs) are increasingly being integrated into various medical fields, including mental health support systems. However, there is a gap in research regarding the effectiveness of LLMs in non-English mental health…

Computation and Language · Computer Science 2026-02-10 Konstantinos Skianis , John Pavlopoulos , A. Seza Doğruöz

Rare diseases pose significant challenges in diagnosis and treatment due to their low prevalence and heterogeneous clinical presentations. Unstructured clinical notes contain valuable information for identifying rare diseases, but manual…

Computation and Language · Computer Science 2024-11-12 Jinge Wu , Hang Dong , Zexi Li , Haowei Wang , Runci Li , Arijit Patra , Chengliang Dai , Waqar Ali , Phil Scordis , Honghan Wu

The increasing prevalence of mental disorders globally highlights the urgent need for effective digital screening methods that can be used in multilingual contexts. Most existing studies, however, focus on English data, overlooking critical…

Computation and Language · Computer Science 2026-01-27 Ana-Maria Bucur , Marcos Zampieri , Tharindu Ranasinghe , Fabio Crestani

Synthetic data generation using large language models (LLMs) demonstrates substantial promise in addressing biomedical data challenges and shows increasing adoption in biomedical research. This study systematically reviews recent advances…

Computation and Language · Computer Science 2026-02-18 Hanshu Rao , Weisi Liu , Haohan Wang , I-Chan Huang , Zhe He , Xiaolei Huang

Large language models (LLMs) are increasingly being used in a zero-shot fashion to assess mental health conditions, yet we have limited knowledge on what factors affect their accuracy. In this study, we utilize a clinical dataset of natural…

The scientific discourse surrounding Chronic Lyme Disease (CLD) and Post-Treatment Lyme Disease Syndrome (PTLDS) has evolved over the past twenty-five years into a complex and polarised debate, shaped by shifting research priorities,…

Computers and Society · Computer Science 2025-04-15 Teo Susnjak , Cole Palffy , Tatiana Zimina , Nazgul Altynbekova , Kunal Garg , Leona Gilbert

The shortage of clinical workforce presents significant challenges in mental healthcare, limiting access to formal diagnostics and services. We aim to tackle this shortage by integrating a customized large language model (LLM) into the…

Computation and Language · Computer Science 2025-05-02 Sichang Tu , Abigail Powers , Natalie Merrill , Negar Fani , Sierra Carter , Stephen Doogan , Jinho D. Choi

Mental health conditions affect hundreds of millions globally, yet early detection remains limited. While large language models (LLMs) have shown promise in mental health applications, their size and computational demands hinder practical…

Artificial Intelligence · Computer Science 2025-12-17 Tianyi Zhang , Xiangyuan Xue , Lingyan Ruan , Shiya Fu , Feng Xia , Simon D'Alfonso , Vassilis Kostakos , Ting Dang , Hong Jia

A biological understanding is key for managing medical conditions, yet psychological and social aspects matter too. The main problem is that these two aspects are hard to quantify and inherently difficult to communicate. To quantify…

Human-Computer Interaction · Computer Science 2020-10-14 Wonyoung So , Edyta P. Bogucka , Sanja Šćepanović , Sagar Joglekar , Ke Zhou , Daniele Quercia

Medical document analysis plays a crucial role in extracting essential clinical insights from unstructured healthcare records, supporting critical tasks such as differential diagnosis. Determining the most probable condition among…

Artificial Intelligence · Computer Science 2025-06-25 Lei Kang , Xuanshuo Fu , Oriol Ramos Terrades , Javier Vazquez-Corral , Ernest Valveny , Dimosthenis Karatzas

Objective Alzheimer disease (AD) is the most common cause of dementia, a syndrome characterized by cognitive impairment severe enough to interfere with activities of daily life. We aimed to conduct a systematic literature review (SLR) of…

Quantitative Methods · Quantitative Biology 2021-08-31 Sayantan Kumar , Inez Oh , Suzanne Schindler , Albert M Lai , Philip R O Payne , Aditi Gupta

Neurological disorders that affect speech production, such as Alzheimer's Disease (AD), significantly impact the lives of both patients and caregivers, whether through social, psycho-emotional effects or other aspects not yet fully…

Large language models (LLMs) chatbots like ChatGPT are increasingly used for mental health support. They offer accessible, therapeutic support but also raise concerns about misinformation, over-reliance, and risks in high-stakes contexts of…

Computers and Society · Computer Science 2025-12-09 Lingyao Li , Xiaoshan Huang , Renkai Ma , Ben Zefeng Zhang , Haolun Wu , Fan Yang , Chen Chen

Personalized longitudinal disease assessment is central to quickly diagnosing, appropriately managing, and optimally adapting the therapeutic strategy of multiple sclerosis (MS). It is also important for identifying the idiosyncratic…

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