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Mental disorders pose a global challenge, aggravated by the shortage of qualified mental health professionals. Mental disorder prediction from social media posts by current LLMs is challenging due to the complexities of sequential text data…

Computation and Language · Computer Science 2024-10-08 Raja Kumar , Kishan Maharaj , Ashita Saxena , Pushpak Bhattacharyya

Large Language Models (LLMs) have been shown to encode clinical knowledge. Many evaluations, however, rely on structured question-answer benchmarks, overlooking critical challenges of interpreting and reasoning about unstructured clinical…

Computation and Language · Computer Science 2026-04-01 Meghal Dani , Muthu Jeyanthi Prakash , Filip Rosa , Zeynep Akata , Stefanie Liebe

Large language models (LLMs) holds significant promise in achieving general medication recommendation systems owing to their comprehensive interpretation of clinical notes and flexibility to medication encoding. We evaluated both…

Information Retrieval · Computer Science 2025-08-05 Zihao Zhao , Chenxiao Fan , Junlong Liu , Zheng Wang , Xiangnan He , Chongming Gao , Juan Li , Fuli Feng

Breast cancer is a significant public health concern and is the leading cause of cancer-related deaths among women. Despite advances in breast cancer treatments, medication non-adherence remains a major problem. As electronic health records…

Computation and Language · Computer Science 2024-07-30 Seibi Kobara , Alireza Rafiei , Masoud Nateghi , Selen Bozkurt , Rishikesan Kamaleswaran , Abeed Sarker

Since the uptake of social media, researchers have mined online discussions to track the outbreak and evolution of specific diseases or chronic conditions such as influenza or depression. To broaden the set of diseases under study, we…

Computers and Society · Computer Science 2021-03-02 Sanja Scepanovic , Luca Maria Aiello , Ke Zhou , Sagar Joglekar , Daniele Quercia

Depression is debilitating, and not uncommon. Indeed, studies of excessive social media users show correlations with depression, ADHD, and other mental health concerns. Given that there is a large number of people with excessive social…

Computation and Language · Computer Science 2023-10-04 Dean Ninalga

Mental health is a significant and growing public health concern. As language usage can be leveraged to obtain crucial insights into mental health conditions, there is a need for large-scale, labeled, mental health-related datasets of users…

Computation and Language · Computer Science 2018-07-12 Arman Cohan , Bart Desmet , Andrew Yates , Luca Soldaini , Sean MacAvaney , Nazli Goharian

Rare diseases affect over 300 million people worldwide and are characterized by complex care pathways, limited clinical expertise, and substantial unmet communication needs throughout the long patient journey. Recent advances in large…

Computation and Language · Computer Science 2026-04-17 Zaifu Zhan , Yu Hou , Kai Yu , Min Zeng , Anita Burgun , Xiaoyi Chen , Rui Zhang

The increasing prevalence of mental health disorders, such as depression, anxiety, and bipolar disorder, calls for immediate need in developing tools for early detection and intervention. Social media platforms, like Reddit, represent a…

Machine Learning · Computer Science 2025-03-12 Qasim Bin Saeed , Ijaz Ahmed

Schizophrenia is one of the most disabling and difficult to treat of all human medical/health conditions, ranking in the top ten causes of disability worldwide. It has been a puzzle in part due to difficulty in identifying its basic,…

Computation and Language · Computer Science 2018-10-23 Efsun Sarioglu Kayi , Mona Diab , Luca Pauselli , Michael Compton , Glen Coppersmith

As the prevalence of mental health challenges, social media has emerged as a key platform for individuals to express their emotions.Deep learning tends to be a promising solution for analyzing mental health on social media. However, black…

Computation and Language · Computer Science 2024-10-15 Wei Zhai , Nan Bai , Qing Zhao , Jianqiang Li , Fan Wang , Hongzhi Qi , Meng Jiang , Xiaoqin Wang , Bing Xiang Yang , Guanghui Fu

Screening questionnaires are used in medicine as a diagnostic aid. Creating them is a long and expensive process, which could potentially be improved through analysis of social media posts related to symptoms and behaviors prior to…

Machine Learning · Computer Science 2024-11-19 Ortal Ashkenazi , Elad Yom-Tov , Liron Vardi David

Large Language Models (LLMs) are increasingly deployed in high-stakes domains such as clinical decision support and medical documentation. However, the robustness of these models against subtle linguistic variations, specifically…

Computation and Language · Computer Science 2026-05-19 Jen-tse Huang , Didi Zhou , Faith Kamau , Amy Oh , Anne R. Links , Mark Dredze , Mary Catherine Beach , Somnath Saha

This paper proposes a new depression detection system based on LLMs that is both interpretable and interactive. It not only provides a diagnosis, but also diagnostic evidence and personalized recommendations based on natural language…

Computation and Language · Computer Science 2023-05-10 Wei Qin , Zetong Chen , Lei Wang , Yunshi Lan , Weijieying Ren , Richang Hong

Large language models (LLMs) have attracted significant attention for potential applications in digital health, while their application in mental health is subject to ongoing debate. This systematic review aims to evaluate the usage of LLMs…

Computers and Society · Computer Science 2024-08-14 Zhijun Guo , Alvina Lai , Johan Hilge Thygesen , Joseph Farrington , Thomas Keen , Kezhi Li

Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system. The progression and severity of MS varies by individual, but it is generally a disabling disease. Although medications have been developed to…

Applications · Statistics 2013-03-06 Joyce C. Ho , Joydeep Ghosh , KP Unnikrishnan

Pain is an inherent part of human existence, manifesting as both physical and emotional experiences, and can be categorized as either acute or chronic. Over the years, extensive research has been conducted to understand the causes of pain…

Computation and Language · Computer Science 2025-07-14 Ancita Maria Andrade , Tanvi Banerjee , Ramakrishna Mundugar

Major depressive disorder (MDD) impacts more than 300 million people worldwide, highlighting a significant public health issue. However, the uneven distribution of medical resources and the complexity of diagnostic methods have resulted in…

Computation and Language · Computer Science 2025-05-02 Yuyang Sha , Hongxin Pan , Wei Xu , Weiyu Meng , Gang Luo , Xinyu Du , Xiaobing Zhai , Henry H. Y. Tong , Caijuan Shi , Kefeng Li

Rare diseases are very difficult to identify among large number of other possible diagnoses. Better availability of patient data and improvement in machine learning algorithms empower us to tackle this problem computationally. In this…

Machine Learning · Computer Science 2016-09-07 Ravi Garg , Shu Dong , Sanjiv Shah , Siddhartha R Jonnalagadda

Despite the impressive capabilities of Large Language Models (LLMs) in general medical domains, questions remain about their performance in diagnosing rare diseases. To answer this question, we aim to assess the diagnostic performance of…

Computational Engineering, Finance, and Science · Computer Science 2024-08-19 Guanchu Wang , Junhao Ran , Ruixiang Tang , Chia-Yuan Chang , Chia-Yuan Chang , Yu-Neng Chuang , Zirui Liu , Vladimir Braverman , Zhandong Liu , Xia Hu