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Medical image segmentation is a pivotal step in diagnostic and therapeutic processes, relying on high-quality annotated data that is often challenging and costly to obtain. Semi-supervised learning offers a promising approach to enhance…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Yuxuan Cheng , Chenxi Shao , Jie Ma , Yunfei Xie , Guoliang Li

We develop a Bayesian bivariate spatial model for multivariate regression analysis applicable to studies examining the influence of genetic variation on brain structure. Our model is motivated by an imaging genetics study of the Alzheimer's…

Methodology · Statistics 2020-05-26 Yin Song , Shufei Ge , Jiguo Cao , Liangliang Wang , Farouk S. Nathoo

In comparative research on time-to-event data for two groups, when two survival curves cross each other, it may be difficult to use the log-rank test and hazard ratio (HR) to properly assess the treatment benefit. Our aim was to identify a…

Methodology · Statistics 2021-12-21 Xinghui Huang , Jingjing Lyu , Yawen Hou , Zheng Chen

Standardized tests play a crucial role in the detection of cognitive impairment. Previous work demonstrated that automatic detection of cognitive impairment is possible using audio data from a standardized picture description task. The…

Neuropsychiatric disorders, such as Alzheimer's disease (AD), depression, and autism spectrum disorder (ASD), are characterized by linguistic and acoustic abnormalities, offering potential biomarkers for early detection. Despite the promise…

Computation and Language · Computer Science 2025-12-25 Zhongren Dong , Haotian Guo , Weixiang Xu , Huan Zhao , Zixing Zhang

Autism Spectrum Disorder (ASD) lacks reliable biological markers, delaying early diagnosis. Using 159 salivary samples analyzed by ATR-FTIR spectroscopy, we developed GANet, a genetic algorithm-based network optimization framework…

Machine Learning · Computer Science 2025-09-22 Janayna M. Fernandes , Robinson Sabino-Silva , Murillo G. Carneiro

Increased variability in performance has been associated with the emergence of several neurological and psychiatric pathologies. However, whether and how consistency of neuronal activity may also be indicative of an underlying pathology is…

Neurons and Cognition · Quantitative Biology 2014-10-31 J. H. Martínez , J. M. Pastor , P. Ariza , M. Zanin , D. Papo , F. Maestú , R. Bajo , S. Boccaletti , J. M. Buldú

The acoustic sensitivity of Autism Spectrum Disorder (ASD) individuals highly impacts their intelligibility in noisy urban environments. In this Letter, the disturbance sensing level is examined with perceptual listening tests that…

Audio and Speech Processing · Electrical Eng. & Systems 2025-05-16 Marcelo Pillonetto , Anderson Queiroz , Rosângela Coelho

With most recent estimates giving an incidence rate of 1 in 68 children in the United States, the autism spectrum disorder (ASD) is a growing public health crisis. Many of these children struggle to make eye contact, recognize facial…

Human-Computer Interaction · Computer Science 2020-04-30 Nick Haber , Catalin Voss , Jena Daniels , Peter Washington , Azar Fazel , Aaron Kline , Titas De , Terry Winograd , Carl Feinstein , Dennis P. Wall

Accurate diagnosis of Autism Spectrum Disorder (ASD) followed by effective rehabilitation is essential for the management of this disorder. Artificial intelligence (AI) techniques can aid physicians to apply automatic diagnosis and…

Autism spectrum disorder (ASD) is associated with atypical large-scale brain organization, yet the functional principles underlying these alterations remain incompletely understood. We examined whether coevolutionary balance, a…

Neurons and Cognition · Quantitative Biology 2026-02-17 S. Rezaei Afshar , G. Reza Jafari

The insufficient supervision limit the performance of the deep supervised models for brain disease diagnosis. It is important to develop a learning framework that can capture more information in limited data and insufficient supervision. To…

Neurons and Cognition · Quantitative Biology 2024-10-10 Wenjing Gao , Yuanyuan Yang , Jianrui Wei , Xuntao Yin , Xinhan Di

Autism Spectrum Disorder (ASD) is a diverse collection of neurobiological conditions marked by challenges in social communication and reciprocal interactions, as well as repetitive and stereotypical behaviors. Atypical behavior patterns in…

Computer Vision and Pattern Recognition · Computer Science 2024-07-15 Abid Ali , Mahmoud Ali , Jean-Marc Odobez , Camilla Barbini , Séverine Dubuisson , Francois Bremond , Susanne Thümmler

In this paper, we introduce a deep learning model to classify children as either healthy or potentially autistic with 94.6% accuracy using Deep Learning. Autistic patients struggle with social skills, repetitive behaviors, and…

Computer Vision and Pattern Recognition · Computer Science 2020-08-10 Madison Beary , Alex Hadsell , Ryan Messersmith , Mohammad-Parsa Hosseini

There has been increasing interests in learning resting-state brain functional connectivity of autism disorders using functional magnetic resonance imaging (fMRI) data. The data in a standard brain template consist of over 200,000 voxel…

Methodology · Statistics 2016-03-22 Jichun Xie , Jian Kang

This paper considers joint analysis of multiple functionally related structures in classification tasks. In particular, our method developed is driven by how functionally correlated brain structures vary together between autism and control…

Machine Learning · Statistics 2021-09-08 Zhiyuan Liu , Jörn Schulz , Mohsen Taheri , Martin Styner , James Damon , Stephen Pizer , J. S. Marron

Mood disorders such as depression and anxiety often manifest through facial expressions, but existing machine learning algorithms designed to assess these disorders have been hindered by small datasets and limited real-world applicability.…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Xiao Xu , Xizhe Zhang , Yan Zhang

Early diagnosis of Autism Spectrum Disorder (ASD) is an effective and favorable step towards enhancing the health and well-being of children with ASD. Manual ASD diagnosis testing is labor-intensive, complex, and prone to human error due to…

Artificial Intelligence · Computer Science 2024-09-30 Chinthaka Ranasingha , Harshala Gammulle , Tharindu Fernando , Sridha Sridharan , Clinton Fookes

Despite the great promise that machine learning has offered in many fields of medicine, it has also raised concerns about potential biases and poor generalization across genders, age distributions, races and ethnicities, hospitals, and data…

Machine Learning · Computer Science 2023-02-01 Rongguang Wang , Pratik Chaudhari , Christos Davatzikos

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition with a wide range of behavioral and cognitive impairments. While genetic and environmental factors are known to contribute to its etiology, the underlying metabolic…

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