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Early infancy is a rapid and dynamic neurodevelopmental period for behavior and neurocognition. Longitudinal magnetic resonance imaging (MRI) is an effective tool to investigate such a crucial stage by capturing the developmental…
Longitudinal brain MRI is essential for lifespan study, yet high attrition rates often lead to missing data, complicating analysis. Deep generative models have been explored, but most rely solely on image intensity, leading to two key…
Understanding and predicting the progression of neurodegenerative diseases remains a major challenge in medical AI, with significant implications for early diagnosis, disease monitoring, and treatment planning. However, most available…
Purpose: To accelerate MRI acquisition by incorporating the previous scans of a subject during reconstruction. Although longitudinal imaging constitutes much of clinical MRI, leveraging previous scans is challenging due to the complex…
In this article, we present a Latent Diffusion Model (LDM) for the generation of brain Magnetic Resonance Imaging (MRI), conditioning its generation based on pathology (Healthy, Glioblastoma, Sclerosis, Dementia) and acquisition modality…
Accurate longitudinal analysis of brain MRI is often hindered by evolving lesions, which bias automated neuroimaging pipelines. While deep generative models have shown promise in inpainting these lesions, most existing methods operate…
Structural and appearance changes in brain imaging over time are crucial indicators of neurodevelopment and neurodegeneration. The rapid advancement of large-scale generative models provides a promising backbone for modeling these complex…
Neurite Orientation Dispersion and Density Imaging (NODDI) is an important imaging technology used to evaluate the microstructure of brain tissue, which is of great significance for the discovery and treatment of various neurological…
Image-to-Image translation models can help mitigate various challenges inherent to medical image acquisition. Latent diffusion models (LDMs) leverage efficient learning in compressed latent space and constitute the core of state-of-the-art…
High-resolution (HR) MRI scans obtained from research-grade medical centers provide precise information about imaged tissues. However, routine clinical MRI scans are typically in low-resolution (LR) and vary greatly in contrast and spatial…
Brain MRI scans are often found in four modalities, consisting of T1-weighted with and without contrast enhancement (T1ce and T1w), T2-weighted imaging (T2w), and Flair. Leveraging complementary information from these different modalities…
Generative models based on deep learning have shown significant potential in medical imaging, particularly for modality transformation and multimodal fusion in MRI-based brain imaging. This study introduces GM-LDM, a novel framework that…
Diffusion priors have been used for blind face restoration (BFR) by fine-tuning diffusion models (DMs) on restoration datasets to recover low-quality images. However, the naive application of DMs presents several key limitations. (i) The…
Accurate segmentation of infant brain MRI is critical for studying early neurodevelopment and diagnosing neurological disorders. Yet, it remains a fundamental challenge due to continuously evolving anatomy of the subjects, motion artifacts,…
Accurately identifying oocytes that progress to the blastocyst stage is crucial in reproductive medicine, but the limited availability of annotated high-quality embryo images presents challenges for developing automated diagnostic tools. To…
Latent Diffusion models (LDMs) have achieved remarkable results in synthesizing high-resolution images. However, the iterative sampling process is computationally intensive and leads to slow generation. Inspired by Consistency Models (song…
Human organs constantly undergo anatomical changes due to a complex mix of short-term (e.g., heartbeat) and long-term (e.g., aging) factors. Evidently, prior knowledge of these factors will be beneficial when modeling their future state,…
Longitudinal fetal brain atlas is a powerful tool for understanding and characterizing the complex process of fetus brain development. Existing fetus brain atlases are typically constructed by averaged brain images on discrete time points…
Ultrasound is a widely accessible and cost-effective medical imaging tool commonly used for prenatal evaluation of the fetal brain. However, it has limitations, particularly in the third trimester, where the complexity of the fetal brain…
Alzheimers disease progresses slowly and involves complex interaction between various biological factors. Longitudinal medical imaging data can capture this progression over time. However, longitudinal data frequently encounter issues such…