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Accurately modeling longitudinal brain MRI progression is crucial for understanding neurodegenerative diseases and predicting individualized structural changes. Existing state-of-the-art approaches, such as Brain Latent Progression (BrLP),…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Cheng Wan , Bahram Jafrasteh , Ehsan Adeli , Miaomiao Zhang , Qingyu Zhao

Synthetic longitudinal brain MRI simulates brain aging and would enable more efficient research on neurodevelopmental and neurodegenerative conditions. Synthetically generated, age-adjusted brain images could serve as valuable alternatives…

Signal Processing · Electrical Eng. & Systems 2024-05-03 Anna Zapaishchykova , Benjamin H. Kann , Divyanshu Tak , Zezhong Ye , Daphne A. Haas-Kogan , Hugo J. W. L. Aerts

Pseudo-healthy image inpainting is an essential preprocessing step for analyzing pathological brain MRI scans. Most current inpainting methods favor slice-wise 2D models for their high in-plane fidelity, but their independence across slices…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Dou Hoon Kwark , Shirui Luo , Xiyue Zhu , Yudu Li , Zhi-Pei Liang , Volodymyr Kindratenko

The scarcity of accessible medical image data poses a significant obstacle in effectively training deep learning models for medical diagnosis, as hospitals refrain from sharing their data due to privacy concerns. In response, we gathered a…

Image and Video Processing · Electrical Eng. & Systems 2024-11-25 Lakshmikar R. Polamreddy , Kalyan Roy , Sheng-Han Yueh , Deepshikha Mahato , Shilpa Kuppili , Jialu Li , Youshan Zhang

Early prediction of Mild Cognitive Impairment (MCI) conversion is hampered by a trade-off between immediacy--making fast predictions from a single baseline sMRI--and accuracy--leveraging longitudinal scans to capture disease progression. We…

Machine Learning · Computer Science 2025-06-09 Zhihao Tang , Chaozhuo Li , Litian Zhang , Xi Zhang

Latent diffusion models (LDMs) have demonstrated remarkable generative capabilities across various low-level vision tasks. However, their potential for point cloud completion remains underexplored due to the unstructured and irregular…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Zijun Li , Hongyu Yan , Shijie Li , Kunming Luo , Li Lu , Xulei Yang , Weisi Lin

Building of atlases plays a crucial role in the analysis of brain images. In scenarios where early growth, aging or disease trajectories are of key importance, longitudinal atlases become necessary as references, most often created from…

Image and Video Processing · Electrical Eng. & Systems 2020-03-12 Heejong Kim , Martin Styner , Joseph Piven , Guido Gerig

Latent Consistency Models (LCMs) have achieved impressive performance in accelerating text-to-image generative tasks, producing high-quality images with minimal inference steps. LCMs are distilled from pre-trained latent diffusion models…

Computer Vision and Pattern Recognition · Computer Science 2023-11-10 Simian Luo , Yiqin Tan , Suraj Patil , Daniel Gu , Patrick von Platen , Apolinário Passos , Longbo Huang , Jian Li , Hang Zhao

Deep neural networks have brought remarkable breakthroughs in medical image analysis. However, due to their data-hungry nature, the modest dataset sizes in medical imaging projects might be hindering their full potential. Generating…

The utilization of longitudinal datasets for glaucoma progression prediction offers a compelling approach to support early therapeutic interventions. Predominant methodologies in this domain have primarily focused on the direct prediction…

Computer Vision and Pattern Recognition · Computer Science 2024-11-06 Zhihao Zhao , Junjie Yang , Shahrooz Faghihroohi , Yinzheng Zhao , Daniel Zapp , Kai Huang , Nassir Navab , M. Ali Nasseri

Interpretability is a key issue when applying deep learning models to longitudinal brain MRIs. One way to address this issue is by visualizing the high-dimensional latent spaces generated by deep learning via self-organizing maps (SOM). SOM…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Jiahong Ouyang , Qingyu Zhao , Ehsan Adeli , Wei Peng , Greg Zaharchuk , Kilian M. Pohl

Missing data problems, such as missing modalities in multi-modal brain MRI and missing slices in cardiac MRI, pose significant challenges in clinical practice. Existing methods rely on external guidance to supply detailed missing state for…

Image and Video Processing · Electrical Eng. & Systems 2026-03-11 Junkai Liu , Nay Aung , Theodoros N. Arvanitis , Joao A. C. Lima , Steffen E. Petersen , Le Zhang

Latent diffusion models have emerged as powerful generative models in medical imaging, enabling the synthesis of high quality brain magnetic resonance imaging scans. In particular, predicting the evolution of a patients brain can aid in…

Computer Vision and Pattern Recognition · Computer Science 2026-04-20 Duy-Phuong Dao , Muhammad Taqiyuddin , Jahae Kim , Sang-Heon Lee , Hye-Won Jung , Jaehoo Choi , Hyung-Jeong Yang

Generative data augmentation with latent diffusion models is a promising strategy for addressing class imbalance in medical imaging, yet current approaches focus on perceptual fidelity and domain-specific autoencoder fine-tuning while…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Mischa Dombrowski , Felix Nützel , Bernhard Kainz

The human brains are organized into hierarchically modular networks facilitating efficient and stable information processing and supporting diverse cognitive processes during the course of development. While the remarkable reconfiguration…

Neurons and Cognition · Quantitative Biology 2020-09-16 Xuyun Wen , Liming Hsu , Weili Lin , Han Zhang , Dinggang Shen

Deep learning-based segmentation techniques have shown remarkable performance in brain segmentation, yet their success hinges on the availability of extensive labeled training data. Acquiring such vast datasets, however, poses a significant…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Jihoon Cho , Suhyun Ahn , Beomju Kim , Hyungjoon Bae , Xiaofeng Liu , Fangxu Xing , Kyungeun Lee , Georges Elfakhri , Van Wedeen , Jonghye Woo , Jinah Park

Reconstructing visual stimuli from human brain activities provides a promising opportunity to advance our understanding of the brain's visual system and its connection with computer vision models. Although deep generative models have been…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Jingyuan Sun , Mingxiao Li , Marie-Francine Moens

Diffusion Probabilistic Models (DPMs) suffer from inefficient inference due to their slow sampling and high memory consumption, which limits their applicability to various medical imaging applications. In this work, we propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Fahim Ahmed Zaman , Mathews Jacob , Amanda Chang , Kan Liu , Milan Sonka , Xiaodong Wu

Multimodal Large Language Models (MLLMs) have demonstrated strong capabilities across a wide range of vision language tasks. However, when applied to large scale image classification, their performance degrades significantly as the label…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Zhipeng Ye , Jiaqi Huang , Feng Jiang , Qiufeng Wang , Yikang Duan , Dawei Wang , Xihang Zhou , Qian Qiao

Diffusion MRI (dMRI) is an advanced imaging technique characterizing tissue microstructure and white matter structural connectivity of the human brain. The demand for high-quality dMRI data is growing, driven by the need for better…

Image and Video Processing · Electrical Eng. & Systems 2024-08-26 Xi Zhu , Wei Zhang , Yijie Li , Lauren J. O'Donnell , Fan Zhang