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Large language models (LLMs) are commonly trained on multi-domain datasets, where domain sampling strategies significantly impact model performance due to varying domain importance across downstream tasks. Existing approaches for optimizing…

Computation and Language · Computer Science 2025-08-25 Weijie Shi , Jipeng Zhang , Yaguang Wu , Jingzhi Fang , Ruiyuan Zhang , Jiajie Xu , Jia Zhu , Hao Chen , Yao Zhao , Sirui Han , Xiaofang Zhou

Foundation models have revolutionized the paradigm of digital pathology, as they leverage general-purpose features to emulate real-world pathological practices, enabling the quantitative analysis of critical histological patterns and the…

Domain adaptation (DA) is a quickly expanding area in machine learning that involves adjusting a model trained in one domain to perform well in another domain. While there have been notable progressions, the fundamental concept of numerous…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Yihang Wu , Ahmad Chaddad

Multiple Instance Learning (MIL) has become the predominant approach for classification tasks on gigapixel histopathology whole slide images (WSIs). Within the MIL framework, single WSIs (bags) are decomposed into patches (instances), with…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Daniel Sens , Ario Sadafi , Francesco Paolo Casale , Nassir Navab , Carsten Marr

Deep learning (DL) models are being deployed at medical centers to aid radiologists for diagnosis of lung conditions from chest radiographs. Such models are often trained on a large volume of publicly available labeled radiographs. These…

Computer Vision and Pattern Recognition · Computer Science 2020-12-22 Abhishek K Dubey , Michael T Young , Christopher Stanley , Dalton Lunga , Jacob Hinkle

While deep learning models become more widespread, their ability to handle unseen data and generalize for any scenario is yet to be challenged. In medical imaging, there is a high heterogeneity of distributions among images based on the…

Image and Video Processing · Electrical Eng. & Systems 2025-05-01 Eduardo H. P. Pooch , Pedro L. Ballester , Rodrigo C. Barros

The ability to adapt medical image segmentation networks for a novel class such as an unseen anatomical or pathological structure, when only a few labelled examples of this class are available from local healthcare providers, is…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 Yiwen Li , Yunguan Fu , Qianye Yang , Zhe Min , Wen Yan , Henkjan Huisman , Dean Barratt , Victor Adrian Prisacariu , Yipeng Hu

Deep Learning (DL) can predict biomarkers directly from digitized cancer histology in a weakly-supervised setting. Recently, the prediction of continuous biomarkers through regression-based DL has seen an increasing interest. Nonetheless,…

Image and Video Processing · Electrical Eng. & Systems 2024-03-07 Omar S. M. El Nahhas , Georg Wölflein , Marta Ligero , Tim Lenz , Marko van Treeck , Firas Khader , Daniel Truhn , Jakob Nikolas Kather

Domain shift in the field of histopathological imaging is a common phenomenon due to the intra- and inter-hospital variability of staining and digitization protocols. The implementation of robust models, capable of creating generalized…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Ilán Carretero , Pablo Meseguer , Rocío del Amor , Valery Naranjo

Purpose: To develop a Breast Imaging Reporting and Data System (BI-RADS) breast density deep learning (DL) model in a multi-site setting for synthetic two-dimensional mammography (SM) images derived from digital breast tomosynthesis exams…

Many medical datasets have recently been created for medical image segmentation tasks, and it is natural to question whether we can use them to sequentially train a single model that (1) performs better on all these datasets, and (2)…

Computer Vision and Pattern Recognition · Computer Science 2022-08-02 Chenyu You , Jinlin Xiang , Kun Su , Xiaoran Zhang , Siyuan Dong , John Onofrey , Lawrence Staib , James S. Duncan

Medical ultrasound image segmentation faces significant challenges due to limited labeled data and characteristic imaging artifacts including speckle noise and low-contrast boundaries. While semi-supervised learning (SSL) approaches have…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Jingguo Qu , Xinyang Han , Yao Pu , Man-Lik Chui , Simon Takadiyi Gunda , Ziman Chen , Jing Qin , Ann Dorothy King , Winnie Chiu-Wing Chu , Jing Cai , Michael Tin-Cheung Ying

Multiple instance learning (MIL) stands as a powerful approach in weakly supervised learning, regularly employed in histological whole slide image (WSI) classification for detecting tumorous lesions. However, existing mainstream MIL methods…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Wenhui Zhu , Xiwen Chen , Peijie Qiu , Aristeidis Sotiras , Abolfazl Razi , Yalin Wang

In many machine learning domains, datasets are characterized by highly imbalanced and overlapping classes. Particularly in the medical domain, a specific list of symptoms can be labeled as one of various different conditions. Some of these…

Machine Learning · Computer Science 2020-06-03 Ran Ilan Ber , Tom Haramaty

Domain shifts in the training data are common in practical applications of machine learning; they occur for instance when the data is coming from different sources. Ideally, a ML model should work well independently of these shifts, for…

Improving the fairness of federated learning (FL) benefits healthy and sustainable collaboration, especially for medical applications. However, existing fair FL methods ignore the specific characteristics of medical FL applications, i.e.,…

Machine Learning · Computer Science 2024-10-29 Yunlu Yan , Lei Zhu , Yuexiang Li , Xinxing Xu , Rick Siow Mong Goh , Yong Liu , Salman Khan , Chun-Mei Feng

The emergence of foundation models in computational pathology has transformed histopathological image analysis, with whole slide imaging (WSI) diagnosis being a core application. Traditionally, weakly supervised fine-tuning via multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Jiawen Li , Jiali Hu , Qiehe Sun , Renao Yan , Minxi Ouyang , Tian Guan , Anjia Han , Chao He , Yonghong He

Bag-based Multiple Instance Learning (MIL) approaches have emerged as the mainstream methodology for Whole Slide Image (WSI) classification. However, most existing methods adopt a segmented training strategy, which first extracts features…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Jiangping Wen , Jinyu Wen , Meie Fang

Domain shift differences between training data for deep learning models and the deployment context can result in severe performance issues for models which fail to generalize. We study the domain shift problem under the context of remote…

Computer Vision and Pattern Recognition · Computer Science 2024-04-15 Nathan Vance , Patrick Flynn

Generating large-scale synthetic data in simulation is a feasible alternative to collecting/labelling real data for training vision-based deep learning models, albeit the modelling inaccuracies do not generalize to the physical world. In…

Computer Vision and Pattern Recognition · Computer Science 2021-01-08 Ajay Kumar Tanwani