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We present a novel approach to train pixel resolution segmentation models on whole slide images in a weakly supervised setup. The model is trained to classify patches extracted from slides. This leads the training to be made under noisy…

Image and Video Processing · Electrical Eng. & Systems 2019-07-19 Nicolas Pinchaud

Learning from Label Proportions (LLP) is a learning setting, where the training data is provided in groups, or "bags", and only the proportion of each class in each bag is known. The task is to learn a model to predict the class labels of…

Machine Learning · Statistics 2015-02-13 Felix X. Yu , Krzysztof Choromanski , Sanjiv Kumar , Tony Jebara , Shih-Fu Chang

The problem of learning from label proportions (LLP) involves training classifiers with weak labels on bags of instances, rather than strong labels on individual instances. The weak labels only contain the label proportion of each bag. The…

Machine Learning · Computer Science 2019-10-30 Kuen-Han Tsai , Hsuan-Tien Lin

This work addresses how to efficiently classify challenging histopathology images, such as gigapixel whole-slide images for cancer diagnostics with image-level annotation. We use images with annotated tumor regions to identify a set of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Mohammad Iqbal Nouyed , Mary-Anne Hartley , Gianfranco Doretto , Donald A. Adjeroh

Insufficient prior knowledge of a captured hyperspectral image (HSI) scene may lead the experts or the automatic labeling systems to offer incorrect labels or ambiguous labels (i.e., assigning each training sample to a group of candidate…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Shujun Yang , Yu Zhang , Yao Ding , Danfeng Hong

Current approaches for classification of whole slide images (WSI) in digital pathology predominantly utilize a two-stage learning pipeline. The first stage identifies areas of interest (e.g. tumor tissue), while the second stage processes…

Computer Vision and Pattern Recognition · Computer Science 2022-07-20 Marvin Teichmann , Andre Aichert , Hanibal Bohnenberger , Philipp Ströbel , Tobias Heimann

Automatic outlining of different tissue types in digitized histological specimen provides a basis for follow-up analyses and can potentially guide subsequent medical decisions. The immense size of whole-slide-images (WSI), however, poses a…

Learning from Label Proportions (LLP) is an established machine learning problem with numerous real-world applications. In this setting, data items are grouped into bags, and the goal is to learn individual item labels, knowing only the…

Machine Learning · Computer Science 2023-10-31 Gabriel Franco , Giovanni Comarela , Mark Crovella

Digital pathology based on whole slide images (WSIs) plays a key role in cancer diagnosis and clinical practice. Due to the high resolution of the WSI and the unavailability of patch-level annotations, WSI classification is usually…

Computer Vision and Pattern Recognition · Computer Science 2023-05-02 Litao Yang , Deval Mehta , Sidong Liu , Dwarikanath Mahapatra , Antonio Di Ieva , Zongyuan Ge

Whole slide images (WSIs) are gigapixel-scale digital images of H\&E-stained tissue samples widely used in pathology. The substantial size and complexity of WSIs pose unique analytical challenges. Multiple Instance Learning (MIL) has…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Jun Wang , Yu Mao , Nan Guan , Chun Jason Xue

We propose a new method for cancer subtype classification from histopathological images, which can automatically detect tumor-specific features in a given whole slide image (WSI). The cancer subtype should be classified by referring to a…

Computer Vision and Pattern Recognition · Computer Science 2020-04-03 Noriaki Hashimoto , Daisuke Fukushima , Ryoichi Koga , Yusuke Takagi , Kaho Ko , Kei Kohno , Masato Nakaguro , Shigeo Nakamura , Hidekata Hontani , Ichiro Takeuchi

Whole slide images (WSIs) pose unique challenges when training deep learning models. They are very large which makes it necessary to break each image down into smaller patches for analysis, image features have to be extracted at multiple…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Ozan Ciga , Tony Xu , Sharon Nofech-Mozes , Shawna Noy , Fang-I Lu , Anne L. Martel

Label Proportion Learning (LLP) addresses the classification problem where multiple instances are grouped into bags and each bag contains information about the proportion of each class. However, in practical applications, obtaining precise…

Machine Learning · Computer Science 2025-07-15 Jiahe Qin , Junpeng Li , Changchun Hua , Yana Yang

Learning with Label Proportions (LLP) is the problem of recovering the underlying true labels given a dataset when the data is presented in the form of bags. This paradigm is particularly suitable in contexts where providing individual…

Machine Learning · Computer Science 2018-10-25 Rafael Poyiadzi , Raul Santos-Rodriguez , Niall Twomey

This paper presents a novel method for unsupervised segmentation of pathology images. Staging of lung cancer is a major factor of prognosis. Measuring the maximum dimensions of the invasive component in a pathology images is an essential…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Takayasu Moriya , Holger R. Roth , Shota Nakamura , Hirohisa Oda , Kai Nagara , Masahiro Oda , Kensaku Mori

Learning from label proportions (LLP) is a weakly supervised setting for classification in which unlabeled training instances are grouped into bags, and each bag is annotated with the proportion of each class occurring in that bag. Prior…

Machine Learning · Statistics 2020-06-15 Clayton Scott , Jianxin Zhang

Partial label learning deals with the problem where each training instance is assigned a set of candidate labels, only one of which is correct. This paper provides the first attempt to leverage the idea of self-training for dealing with…

Machine Learning · Computer Science 2019-02-11 Lei Feng , Bo An

Partial label learning (PLL) is a significant weakly supervised learning framework, where each training example corresponds to a set of candidate labels and only one label is the ground-truth label. For the first time, this paper…

Machine Learning · Computer Science 2025-05-07 Yutong Xie , Fuchao Yang , Yuheng Jia

Multiple instance learning (MIL) models have achieved remarkable success in analyzing whole slide images (WSIs) for disease classification problems. However, with regard to gigapixel WSI classification problems, current MIL models are often…

Computer Vision and Pattern Recognition · Computer Science 2023-12-14 Ziyu Su , Mostafa Rezapour , Usama Sajjad , Metin Nafi Gurcan , Muhammad Khalid Khan Niazi

Whole slide image (WSI) classification is a fundamental task for the diagnosis and treatment of diseases; but, curation of accurate labels is time-consuming and limits the application of fully-supervised methods. To address this, multiple…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Philip Chikontwe , Soo Jeong Nam , Heounjeong Go , Meejeong Kim , Hyun Jung Sung , Sang Hyun Park