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Whole-slide image (WSI) analysis plays a crucial role in cancer diagnosis and treatment. In addressing the demands of this critical task, self-supervised learning (SSL) methods have emerged as a valuable resource, leveraging their…

Computer Vision and Pattern Recognition · Computer Science 2023-12-13 Gia-Bao Le , Van-Tien Nguyen , Trung-Nghia Le , Minh-Triet Tran

Partial label learning (PLL) is a typical weakly supervised learning problem, where each training example is associated with a set of candidate labels among which only one is true. Most existing PLL approaches assume that the incorrect…

Machine Learning · Computer Science 2023-02-02 Congyu Qiao , Ning Xu , Xin Geng

In the last few years, deep learning classifiers have shown promising results in image-based medical diagnosis. However, interpreting the outputs of these models remains a challenge. In cancer diagnosis, interpretability can be achieved by…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Kangning Liu , Yiqiu Shen , Nan Wu , Jakub Chłędowski , Carlos Fernandez-Granda , Krzysztof J. Geras

The segmentation of metastatic bone disease (MBD) in whole-body MRI (WB-MRI) is a challenging problem. Due to varying appearances and anatomical locations of lesions, ambiguous boundaries, and severe class imbalance, obtaining reliable…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Joris Wuts , Jakub Ceranka , Nicolas Michoux , Frédéric Lecouvet , Jef Vandemeulebroucke

Learning from Label Proportion (LLP) is a weakly supervised learning scenario in which training data is organized into predefined bags of instances, disclosing only the class label proportions per bag. This paradigm is essential for user…

Machine Learning · Computer Science 2024-08-14 Jialiang Wang , Ning Zhang , Shimin Di , Ruidong Wang , Lei Chen

Machine learning has achieved impressive performance in tomographic reconstruction, but supervised training requires paired measurements and ground-truth images that are often unavailable. This has motivated self-supervised approaches,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-20 Markus Haltmeier , Lukas Neumann , Nadja Gruber , Gyeongha Hwang

The data-driven nature of deep learning (DL) models for semantic segmentation requires a large number of pixel-level annotations. However, large-scale and fully labeled medical datasets are often unavailable for practical tasks. Recently,…

Computer Vision and Pattern Recognition · Computer Science 2021-10-27 Nanqing Dong , Michael Kampffmeyer , Xiaodan Liang , Min Xu , Irina Voiculescu , Eric P. Xing

Complementary-label learning (CLL) is widely used in weakly supervised classification, but it faces a significant challenge in real-world datasets when confronted with class-imbalanced training samples. In such scenarios, the number of…

Machine Learning · Computer Science 2024-03-21 Meng Wei , Yong Zhou , Zhongnian Li , Xinzheng Xu

Fully supervised deep neural networks for segmentation usually require a massive amount of pixel-level labels which are manually expensive to create. In this work, we develop a multi-task learning method to relax this constraint. We regard…

Computer Vision and Pattern Recognition · Computer Science 2021-04-07 Rihuan Ke , Aurélie Bugeau , Nicolas Papadakis , Mark Kirkland , Peter Schuetz , Carola-Bibiane Schönlieb

Researchers working on computational analysis of Whole Slide Images (WSIs) in histopathology have primarily resorted to patch-based modelling due to large resolution of each WSI. The large resolution makes WSIs infeasible to be fed directly…

Computer Vision and Pattern Recognition · Computer Science 2021-06-08 Suvidha Tripathi , Satish Kumar Singh , Hwee Kuan Lee

Various multi-instance learning (MIL) based approaches have been developed and successfully applied to whole-slide pathological images (WSI). Existing MIL methods emphasize the importance of feature aggregators, but largely neglect the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Yicheng Song , Tiancheng Lin , Die Peng , Su Yang , Yi Xu

Weakly supervised machine learning algorithms are able to learn from ambiguous samples or labels, e.g., multi-instance learning or partial-label learning. However, in some real-world tasks, each training sample is associated with not only…

Machine Learning · Computer Science 2022-12-20 Wei Tang , Weijia Zhang , Min-Ling Zhang

Existing approaches for the problem of ultrasound image segmentation, whether supervised or semi-supervised, are typically specialized for specific anatomical structures or tasks, limiting their practical utility in clinical settings. In…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Yaxiong Chen , Qicong Wang , Chunlei Li , Jingliang Hu , Yilei Shi , Shengwu Xiong , Xiao Xiang Zhu , Lichao Mou

Scarcity of high quality annotated images remains a limiting factor for training accurate image segmentation models. While more and more annotated datasets become publicly available, the number of samples in each individual database is…

Computer Vision and Pattern Recognition · Computer Science 2021-07-14 Gregory Filbrandt , Konstantinos Kamnitsas , David Bernstein , Alexandra Taylor , Ben Glocker

Weakly supervised segmentation methods can delineate thyroid nodules in ultrasound images efficiently using training data with coarse labels, but suffer from: 1) low-confidence pseudo-labels that follow topological priors, introducing…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Jianning Chi , Zelan Li , Geng Lin , MingYang Sun , Xiaosheng Yu

Deep learning has become the mainstream methodological choice for analyzing and interpreting whole-slide digital pathology images (WSIs). It is commonly assumed that tumor regions carry most predictive information. In this paper, we…

Quantitative Methods · Quantitative Biology 2022-04-26 Zihan Chen , Xingyu Li , Miaomiao Yang , Hong Zhang , Xu Steven Xu

We present WeakSTIL, an interpretable two-stage weak label deep learning pipeline for scoring the percentage of stromal tumor infiltrating lymphocytes (sTIL%) in H&E-stained whole-slide images (WSIs) of breast cancer tissue. The sTIL% score…

Image and Video Processing · Electrical Eng. & Systems 2021-09-14 Yoni Schirris , Mendel Engelaer , Andreas Panteli , Hugo Mark Horlings , Efstratios Gavves , Jonas Teuwen

Partial Label Learning (PLL) aims to learn from the data where each training example is associated with a set of candidate labels, among which only one is correct. The key to deal with such problem is to disambiguate the candidate label…

Machine Learning · Computer Science 2019-01-11 Gengyu Lyu , Songhe Feng , Tao Wang , Congyan Lang , Yidong Li

Traditional supervised medical image segmentation models require large amounts of labeled data for training; however, obtaining such large-scale labeled datasets in the real world is extremely challenging. Recent semi-supervised…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Yunyao Lu , Yihang Wu , Reem Kateb , Ahmad Chaddad

Deep-learning (DL) based methods are playing an important role in the task of abdominal organs and tumors segmentation in CT scans. However, the large requirements of annotated datasets heavily limit its development. The FLARE23 challenge…

Image and Video Processing · Electrical Eng. & Systems 2023-10-03 Jiaxin Zhuang , Luyang Luo , Zhixuan Chen , Linshan Wu
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