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Longitudinal fetal brain atlas is a powerful tool for understanding and characterizing the complex process of fetus brain development. Existing fetus brain atlases are typically constructed by averaged brain images on discrete time points…

Image and Video Processing · Electrical Eng. & Systems 2022-09-15 Lixuan Chen , Jiangjie Wu , Qing Wu , Hongjiang Wei , Yuyao Zhang

In the human brain, internal states are often correlated over time (due to local recurrence and other intrinsic circuit properties), punctuated by abrupt transitions. At first glance, temporal smoothness of internal states presents a…

Machine Learning · Computer Science 2023-05-24 Shima Rahimi Moghaddam , Fanjun Bu , Christopher J. Honey

Subjective cognitive decline (SCD) is a preclinical stage of Alzheimer's disease (AD) which occurs even before mild cognitive impairment (MCI). Progressive SCD will convert to MCI with the potential of further evolving to AD. Therefore,…

Computer Vision and Pattern Recognition · Computer Science 2023-02-17 Hao Guan , Ling Yue , Pew-Thian Yap , Shifu Xiao , Andrea Bozoki , Mingxia Liu

Objective: Hydrocephalus is a medical condition in which there is an abnormal accumulation of cerebrospinal fluid (CSF) in the brain. Segmentation of brain imagery into brain tissue and CSF (before and after surgery, i.e. pre-op vs. postop)…

Image and Video Processing · Electrical Eng. & Systems 2018-09-11 Venkateswararao Cherukuri , Peter Ssenyonga , Benjamin C. Warf , Abhaya V. Kulkarni , Vishal Monga , Steven J. Schiff

Self-supervised learning methods based on data augmentations, such as SimCLR, BYOL, or DINO, allow obtaining semantically meaningful representations of image datasets and are widely used prior to supervised fine-tuning. A recent…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Ifeoma Veronica Nwabufo , Jan Niklas Böhm , Philipp Berens , Dmitry Kobak

Self-supervised learning (SSL) has emerged as a promising paradigm for addressing the annotation bottleneck in medical imaging by learning representations from unlabeled data. However, its effectiveness depends heavily on the design of the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Chathura Wimalasiri

Hyperbolic geometry has been successfully applied in modeling brain cortical and subcortical surfaces with general topological structures. However such approaches, similar to other surface based brain morphology analysis methods, usually…

Image and Video Processing · Electrical Eng. & Systems 2021-02-23 J. Zhang , Q. Dong , J. Shi , Q. Li , C. M. Stonnington , B. A. Gutman , K. Chen , E. M. Reiman , R. J. Caselli , P. M. Thompson , J. Ye , Y. Wang

We consider the problem of using a factor model we call {\em spike-and-slab sparse coding} (S3C) to learn features for a classification task. The S3C model resembles both the spike-and-slab RBM and sparse coding. Since exact inference in…

Machine Learning · Statistics 2012-04-05 Ian J. Goodfellow , Aaron Courville , Yoshua Bengio

Modern deep learning-based clinical imaging workflows rely on accurate labels of the examined anatomical region. Knowing the anatomical region is required to select applicable downstream models and to effectively generate cohorts of high…

Computer Vision and Pattern Recognition · Computer Science 2024-12-23 Simon Langer , Jessica Ritter , Rickmer Braren , Daniel Rueckert , Paul Hager

Deploying reliable deep learning techniques in interdisciplinary applications needs learned models to output accurate and (even more importantly) explainable predictions. Existing approaches typically explicate network outputs in a post-hoc…

Machine Learning · Computer Science 2023-05-26 Chenyu Xue , Fan Wang , Yuanzhuo Zhu , Hui Li , Deyu Meng , Dinggang Shen , Chunfeng Lian

Prenatal psychological stress affects 15-25% of pregnancies and increases risks of preterm birth, low birth weight, and adverse neurodevelopmental outcomes. Current screening relies on subjective questionnaires (PSS-10), limiting continuous…

Quantitative Methods · Quantitative Biology 2026-04-28 Martin G. Frasch , Marlene J. E. Mayer , Clara Becker , Peter Zimmermann , Camilla Zelgert , Marta C. Antonelli , Silvia M. Lobmaier

Recent advancements in understanding the brain's functional organization related to behavior have been pivotal, particularly in the development of predictive models based on brain connectivity. Traditional methods in this domain often…

Applications · Statistics 2024-08-01 Wanwan Xu , Selena Wang , Chichun Tan , Xilin Shen , Wenjing Luo , Todd Constable , Tianxi Li , Yize Zhao

In the pregnant mother and her fetus, chronic prenatal stress results in entrainment of the fetal heartbeat by the maternal heartbeat, quantified by the fetal stress index (FSI). Deep learning (DL) is capable of pattern detection in complex…

Quantitative Methods · Quantitative Biology 2021-12-20 Pritam Sarkar , Silvia Lobmaier , Bibiana Fabre , Diego González , Alexander Mueller , Martin G. Frasch , Marta C. Antonelli , Ali Etemad

The self-supervised pretraining paradigm has achieved great success in learning 3D action representations for skeleton-based action recognition using contrastive learning. However, learning effective representations for skeleton-based…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Qiushuo Cheng , Jingjing Liu , Catherine Morgan , Alan Whone , Majid Mirmehdi

Self-supervised pre-training of deep learning models with contrastive learning is a widely used technique in image analysis. Current findings indicate a strong potential for contrastive pre-training on medical images. However, further…

Image and Video Processing · Electrical Eng. & Systems 2024-10-21 Daniel Wolf , Tristan Payer , Catharina Silvia Lisson , Christoph Gerhard Lisson , Meinrad Beer , Michael Götz , Timo Ropinski

The plasticity of the conduction delay between neurons plays a fundamental role in learning. However, the exact underlying mechanisms in the brain for this modulation is still an open problem. Understanding the precise adjustment of…

Neural and Evolutionary Computing · Computer Science 2020-11-19 Alireza Nadafian , Mohammad Ganjtabesh

Contrastive learning (CL) has become a cornerstone of self-supervised pretraining (SSP) in foundation models, however, extending CL to pixel-wise representation, crucial for medical vision, remains an open problem. Standard CL formulates…

Computer Vision and Pattern Recognition · Computer Science 2025-06-27 Yuting He , Shuo Li

The brain-age gap is one of the most investigated risk markers for brain changes across disorders. While the field is progressing towards large-scale models, recently incorporating uncertainty estimates, no model to date provides the…

Time series classification is a critical task in various domains, such as finance, healthcare, and sensor data analysis. Unsupervised contrastive learning has garnered significant interest in learning effective representations from time…

Machine Learning · Computer Science 2025-03-24 Huili Cai , Xiang Zhang , Xiaofeng Liu

Self-supervised foundation models have recently been successfully extended to encode three-dimensional (3D) computed tomography (CT) images, with excellent performance across several downstream tasks, such as intracranial hemorrhage…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Guangyao Zheng , Michael A. Jacobs , Vishwa S. Parekh