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Quantification of brain morphology has become an important cornerstone in understanding brain structure. Measures of cortical morphology such as thickness and surface area are frequently used to compare groups of subjects or characterise…

Neurons and Cognition · Quantitative Biology 2020-03-25 Yujiang Wang , Tobias Ludwig , Bethany Little , Joe H Necus , Gavin Winston , Sjoerd B Vos , Jane de Tisi , John S Duncan , Peter N Taylor , Bruno Mota

Recent work suggests that large-scale, multi-animal modeling can significantly improve neural recording analysis. However, for functional calcium traces, existing approaches remain task-specific, limiting transfer across common neuroscience…

Quantitative Methods · Quantitative Biology 2026-04-09 Xinhong Xu , Yimeng Zhang , Qichen Qian , Yuanlong Zhang

Learning requires the traversal of inherently distinct cognitive states to produce behavioral adaptation. Yet, tools to explicitly measure these states with non-invasive imaging -- and to assess their dynamics during learning -- remain…

Preterm infants (born between 28 and 37 weeks of gestation) face elevated risks of neurodevelopmental delays, making early identification crucial for timely intervention. While deep learning-based volumetric segmentation of brain MRI scans…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Lexin Ren , Jiamiao Lu , Weichuan Zhang , Benqing Wu , Tuo Wang , Yi Liao , Jiapan Guo , Changming Sun , Liang Guo

Brain signals are important quantitative data for understanding physiological activities and diseases of human brain. Most existing studies pay attention to supervised learning methods, which, however, require high-cost clinical labels. In…

Signal Processing · Electrical Eng. & Systems 2023-06-26 Donghong Cai , Junru Chen , Yang Yang , Teng Liu , Yafeng Li

We address the problem of compressed sensing using a deep generative prior model and consider both linear and learned nonlinear sensing mechanisms, where the nonlinear one involves either a fully connected neural network or a convolutional…

Machine Learning · Computer Science 2021-05-26 Vinayak Killedar , Praveen Kumar Pokala , Chandra Sekhar Seelamantula

We develop a mathematical model of information transmission across the biological neural network of the human brain. The overall function of the brain consists of the emergent processes resulting from the spread of information through the…

Biological Physics · Physics 2018-01-22 Stefanie Heyden , Michael Ortiz

Learning robust representations to discriminate cell phenotypes based on microscopy images is important for drug discovery. Drug development efforts typically analyse thousands of cell images to screen for potential treatments. Early works…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Alexis Perakis , Ali Gorji , Samriddhi Jain , Krishna Chaitanya , Simone Rizza , Ender Konukoglu

Continuous unsupervised representation learning (CURL) research has greatly benefited from improvements in self-supervised learning (SSL) techniques. As a result, existing CURL methods using SSL can learn high-quality representations…

Machine Learning · Computer Science 2023-09-13 Alex Gomez-Villa , Bartlomiej Twardowski , Kai Wang , Joost van de Weijer

Recent successes in self-supervised learning (SSL) model spatial co-occurrences of visual features either by masking portions of an image or by aggressively cropping it. Here, we propose a new way to model spatial co-occurrences by aligning…

Machine Learning · Computer Science 2025-01-07 Arthur Aubret , Céline Teulière , Jochen Triesch

Self-supervised learning (SSL) plays a central role in molecular representation learning. Yet, many recent innovations in masking-based pretraining are introduced as heuristics and lack principled evaluation, obscuring which design choices…

Machine Learning · Computer Science 2025-12-09 Jiannan Yang , Veronika Thost , Tengfei Ma

Building accurate and robust artificial intelligence systems for medical image assessment requires not only the research and design of advanced deep learning models but also the creation of large and curated sets of annotated training…

Computer Vision and Pattern Recognition · Computer Science 2022-01-05 Florin C. Ghesu , Bogdan Georgescu , Awais Mansoor , Youngjin Yoo , Dominik Neumann , Pragneshkumar Patel , R. S. Vishwanath , James M. Balter , Yue Cao , Sasa Grbic , Dorin Comaniciu

Human ability to recognize complex visual patterns arises through transformations performed by successive areas in the ventral visual cortex. Deep neural networks trained end-to-end for object recognition approach human capabilities, and…

Neurons and Cognition · Quantitative Biology 2024-11-12 Nikhil Parthasarathy , Olivier J. Hénaff , Eero P. Simoncelli

Deep learning algorithms for predicting neuroimaging data have shown considerable promise in various applications. Prior work has demonstrated that deep learning models that take advantage of the data's 3D structure can outperform standard…

Image and Video Processing · Electrical Eng. & Systems 2023-03-07 Yuda Bi , Anees Abrol , Zening Fu , Jiayu Chen , Jingyu Liu , Vince Calhoun

Semi-supervised learning methods have achieved excellent performance on standard benchmark datasets using very few labelled images. Anatomy classification in fetal 2D ultrasound is an ideal problem setting to test whether these results…

Computer Vision and Pattern Recognition · Computer Science 2019-09-02 Jeremy Tan , Anselm Au , Qingjie Meng , Bernhard Kainz

Long-tailed recognition with imbalanced class distribution naturally emerges in practical machine learning applications. Existing methods such as data reweighing, resampling, and supervised contrastive learning enforce the class balance…

Computer Vision and Pattern Recognition · Computer Science 2023-09-12 Chengkai Hou , Jieyu Zhang , Haonan Wang , Tianyi Zhou

To solve the spatial problems of mapping, localization and navigation, the mammalian lineage has developed striking spatial representations. One important spatial representation is the Nobel-prize winning grid cells: neurons that represent…

Machine Learning · Computer Science 2023-11-07 Rylan Schaeffer , Mikail Khona , Tzuhsuan Ma , Cristóbal Eyzaguirre , Sanmi Koyejo , Ila Rani Fiete

The objective of this paper is to learn semantic representations for sleep stage classification from raw physiological time series. Although supervised methods have gained remarkable performance, they are limited in clinical situations due…

Signal Processing · Electrical Eng. & Systems 2021-10-20 Hongjun Zhang , Jing Wang , Qinfeng Xiao , Jiaoxue Deng , Youfang Lin

In early years of life, the cranium rapidly changes in size and shape to accommodate brain growth, primarily driven by mechanical stress from brain expansion. Developmental disorders such as premature fusion of sutures in craniosynostosis,…

Tissues and Organs · Quantitative Biology 2025-10-30 Mahtab Vafaeefar , Conall Quinn , Ted J. Vaughan

Contrastive, self-supervised learning (SSL) is used to train a model that predicts cancer type from miRNA, mRNA or RPPA expression data. This model, a pretrained FT-Transformer, is shown to outperform XGBoost and CatBoost, standard…

Machine Learning · Computer Science 2023-11-17 Christian John Hurry , Emma Slade