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The mechanisms of cold- and pressure-denaturation of proteins are matter of debate and are commonly understood as due to water-mediated interactions. Here we study several cases of proteins, with or without a unique native state, with or…

Biological Physics · Physics 2026-01-13 Valentino Bianco , Giancarlo Franzese

We study the thermodynamic behavior of a simple off-lattice model for protein folding. The model is two-dimensional and has two different ``amino acids''. Using numerical simulations of all chains containing eight or ten monomers, we…

chem-ph · Physics 2009-10-28 Anders Irbäck , Frank Potthast

Post-transductional modifications tune the functions of proteins and regulate the collective dynamics of biochemical networks that determine how cells respond to environmental signals. For example, protein phosphorylation and nitrosylation…

Cell Behavior · Quantitative Biology 2009-11-13 Roberto Chignola , Chiara Dalla Pellegrina , Alessio Del Fabbro , Edoardo Milotti

Statistical mechanics is founded on the assumption that a system can reach thermal equilibrium, regardless of the starting state. Interactions between particles facilitate thermalization, but, can interacting systems always equilibrate…

In this review the debated rapport between thermodynamics and quantum mechanics is addressed in the framework of the theory of periodically-driven/controlled quantum-thermodynamic machines. The basic model studied here is that of a…

Quantum Physics · Physics 2015-09-15 D. Gelbwaser-Klimovsky , Wolfgang Niedenzu , Gershon Kurizki

A simple model of quantum particle is proposed in which the particle in a {\it macroscopic} rest frame is represented by a {\it microscopic d}-dimensional oscillator, {\it s=(d-1)/2} being the spin of the particle. The state vectors are…

Quantum Physics · Physics 2007-05-23 Blagowest Nikolov

We report the observation of entanglement between a single trapped atom and a single photon at a wavelength suitable for low-loss communication over large distances, thereby achieving a crucial step towards long range quantum networks. To…

The time sequences of the molecular dynamics simulation for the folding process of a protein is analyzed with the inherent structure landscape which focuses on configurational dynamics of the system. Time dependent energy and entropy for…

Statistical Mechanics · Physics 2013-02-13 Naoko Nakagawa

Atoms can be trapped and guided using nano-fabricated wires on surfaces, achieving the scales required by quantum information proposals. These Atom Chips form the basis for robust and widespread applications of cold atoms ranging from atom…

In this article it will be introduced a new theorem, can be considered a generalization of Hellmann-Feynman theorem[1]. The latter used in conjunction with the quantization of the free energy[2] of a quantum system allows to derive…

Materials Science · Physics 2020-12-02 S. Selenu

We investigate the quantum thermodynamics of two quantum systems, a two-level system and a four-level quantum photocell, each driven by photon pulses as a quantum heat engine. We set these systems to be in thermal contact only with a cold…

Quantum Physics · Physics 2020-07-15 Sangchul Oh , Jungjun Park , Hyunchul Nha

Attempts to understand zero temperature phase transitions have forced physicists to consider a regime where the standard paradigms of condensed matter physics break down [1-4]. These quantum critical systems lack a simple description in…

Quantum Gases · Physics 2012-07-04 Kaden R. A. Hazzard , Erich J. Mueller

Transmission through a quantum point contact (QPC) in the quantum Hall regime usually exhibits multiple resonances as a function of gate voltage and high nonlinearity in bias. Such behavior is unpredictable and changes sample by sample.…

Mesoscale and Nanoscale Physics · Physics 2017-12-12 Changki Hong , Jinhong Park , Yunchul Chung , Hyungkook Choi , Vladimir Umansky

One explanation of the thermalization of an isolated quantum system is the eigenstate thermalization hypothesis, which posits that all energy eigenstates are thermal. Based on this idea, we use dynamical typicality to predict the thermal…

A previously established multiscale population genetics model states that fitness can be inferred from the physical properties of proteins under the physiological assumption that a loss of stability by any protein confers the lethal…

Biomolecules · Quantitative Biology 2009-06-03 Peiqiu Chen , Eugene I. Shakhnovich

Starting from a Huxley-type model for an agitated vibrational mode, we propose an embedding of standard active particle models in terms of two-temperature processes. One temperature refers to an ambient thermal bath, and the other…

Statistical Mechanics · Physics 2024-07-02 Faezeh Khodabandehlou , Christian Maes

Novel physical mechanism is proposed for explanation of temperature-independent transition reactions in molecular systems. The mechanism becomes effective in the case of conformation transitions between quasi-isoenergetic molecular states.…

Statistical Mechanics · Physics 2012-11-01 V. I. Teslenko , E. G. Petrov , A. Verkhratsky , O. A. Krishtal

Equations that govern the temperature-dependence of the rate constants, Gibbs energies,enthalpies, entropies and heat capacities of activation for folding and unfolding of spontaneously-folding fixed two-state systems have been derived…

Soft Condensed Matter · Physics 2016-05-11 Robert S. Sade

A thermodynamic theory is developed to describe the behavior of the entanglement between the coin and position degrees of freedom of the quantum walk on the line. This theory shows that, in spite of the unitary evolution, a steady state is…

Quantum Physics · Physics 2011-08-31 Alejandro Romanelli

We show that, in general, any complex weakly nonlinear highly multimode system can reach thermodynamic equilibrium that is characterized by a unique temperature and chemical potential. The conditions leading to either positive or negative…