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Summary: In anticipation of the individualized proteomics era and the need to integrate knowledge from disease studies, we have augmented our peptide identification software RAId DbS to take into account annotated single amino acid…

Quantitative Methods · Quantitative Biology 2008-03-18 Gelio Alves , Aleksey Ogurtsov , Yi-Kuo Yu

Learning the distance metric between pairs of samples has been studied for image retrieval and clustering. With the remarkable success of pair-based metric learning losses, recent works have proposed the use of generated synthetic points on…

Computer Vision and Pattern Recognition · Computer Science 2020-04-24 Byungsoo Ko , Geonmo Gu

Deep metric learning aims to learn a function mapping image pixels to embedding feature vectors that model the similarity between images. Two major applications of metric learning are content-based image retrieval and face verification. For…

Computer Vision and Pattern Recognition · Computer Science 2019-08-06 Andrew Zhai , Hao-Yu Wu

Distribution matching (DM) is a versatile domain-invariant representation learning technique that has been applied to tasks such as fair classification, domain adaptation, and domain translation. Non-parametric DM methods struggle with…

Machine Learning · Computer Science 2025-06-18 Ziyu Gong , Jim Lim , David I. Inouye

Protein-DNA interactions are crucial for all biological processes. One of the most important fundamental aspects of these interactions is the process of protein searching and recognizing specific binding sites on DNA. A large number of…

Subcellular Processes · Quantitative Biology 2015-09-30 Martin Lange , Maria Kochugaeva , Anatoly B. Kolomeisky

Deep learning has revolutionized many industries by enabling models to automatically learn complex patterns from raw data, reducing dependence on manual feature engineering. However, deep learning algorithms are sensitive to input data, and…

Machine Learning · Computer Science 2025-07-21 Mert Sehri , Zehui Hua , Francisco de Assis Boldt , Patrick Dumond

Protein similarity searches are a routine job for molecular biologists where a query sequence of amino acids needs to be compared and ranked against an ever-growing database of proteins. All available algorithms in this field can be grouped…

Computational Engineering, Finance, and Science · Computer Science 2015-08-27 Akash Nag , Sunil Karforma

Deep learning algorithms vary depending on the underlying connection mechanism of nodes of them. They have various hyperparameters that are either set via specific algorithms or randomly chosen. Meanwhile, hyperparameters of deep learning…

Machine Learning · Computer Science 2020-11-20 M. M. Ozturk

Deep learning based methods have seen a massive rise in popularity for hyperspectral image classification over the past few years. However, the success of deep learning is attributed greatly to numerous labeled samples. It is still very…

Computer Vision and Pattern Recognition · Computer Science 2021-06-30 Bing Liu , Anzhu Yu , Pengqiang Zhang , Lei Ding , Wenyue Guo , Kuiliang Gao , Xibing Zuo

Finding correspondences between images or 3D scans is at the heart of many computer vision and image retrieval applications and is often enabled by matching local keypoint descriptors. Various learning approaches have been applied in the…

Computer Vision and Pattern Recognition · Computer Science 2018-05-10 Georgios Georgakis , Srikrishna Karanam , Ziyan Wu , Jan Ernst , Jana Kosecka

Semi-supervised learning provides an expressive framework for exploiting unlabeled data when labels are insufficient. Previous semi-supervised learning methods typically match model predictions of different data-augmented views in a…

Computer Vision and Pattern Recognition · Computer Science 2023-10-26 Cong Wang , Xiaofeng Cao , Lanzhe Guo2 , Zenglin Shi

Deep hashing enables image retrieval by end-to-end learning of deep representations and hash codes from training data with pairwise similarity information. Subject to the distribution skewness underlying the similarity information, most…

Computer Vision and Pattern Recognition · Computer Science 2018-09-06 Zhangjie Cao , Ziping Sun , Mingsheng Long , Jianmin Wang , Philip S. Yu

Tandem repeats in proteins identification, classification and curation is a complex process that requires manual processing from experts, processing power and time. There are recent and relevant advances applying machine learning for…

Software Engineering · Computer Science 2024-07-11 Manuel Bezerra-Brandao , Ronaldo Romario Tunque Cahui , Layla Hirsh

The use of deep learning models in computational biology has increased massively in recent years, and it is expected to continue with the current advances in the fields such as Natural Language Processing. These models, although able to…

We present a novel view of nonlinear manifold learning using derivative-free optimization techniques. Specifically, we propose an extension of the classical multi-dimensional scaling (MDS) method, where instead of performing gradient…

This paper describes several improvements to a new method for signal decomposition that we recently formulated under the name of Differentiable Dictionary Search (DDS). The fundamental idea of DDS is to exploit a class of powerful deep…

Audio and Speech Processing · Electrical Eng. & Systems 2022-11-29 Lukáš Samuel Marták , Rainer Kelz , Gerhard Widmer

Data reduction in storage systems is becoming increasingly important as an effective solution to minimize the management cost of a data center. To maximize data-reduction efficiency, existing post-deduplication delta-compression techniques…

Machine Learning · Computer Science 2022-02-23 Jisung Park , Jeoggyun Kim , Yeseong Kim , Sungjin Lee , Onur Mutlu

As the structural databases continue to expand, efficient methods are required to search similar structures of the query structure from the database. There are many previous works about comparing protein 3D structures and scanning the…

Databases · Computer Science 2011-02-16 Gook-Pil Roh , Seung-won Hwang , Byoung-Kee Yi

Enterprises grapple with the significant challenge of managing proprietary unstructured data, hindering efficient information retrieval. This has led to the emergence of AI-driven information retrieval solutions, designed to adeptly extract…

Protein interactions are important in a broad range of biological processes. Traditionally, computational methods have been developed to automatically predict protein interface from hand-crafted features. Recent approaches employ deep…

Machine Learning · Computer Science 2020-07-21 Yi Liu , Hao Yuan , Lei Cai , Shuiwang Ji