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In this paper, we address the segmentation of tumor subtypes in whole slide images (WSI) by utilizing incomplete label proportions. Specifically, we utilize `partial' label proportions, which give the proportions among tumor subtypes but do…

Computer Vision and Pattern Recognition · Computer Science 2024-05-16 Shinnosuke Matsuo , Daiki Suehiro , Seiichi Uchida , Hiroaki Ito , Kazuhiro Terada , Akihiko Yoshizawa , Ryoma Bise

We propose a method to accurately obtain the ratio of tumor cells over an entire histological slide. We use deep fully convolutional neural network models trained to detect and classify cells on images of H&E-stained tissue sections.…

Image and Video Processing · Electrical Eng. & Systems 2021-01-29 Eric Cosatto , Kyle Gerard , Hans-Peter Graf , Maki Ogura , Tomoharu Kiyuna , Kanako C. Hatanaka , Yoshihiro Matsuno , Yutaka Hatanaka

Learning from Label Proportions (LLP) is a weakly supervised learning method that aims to perform instance classification from training data consisting of pairs of bags containing multiple instances and the class label proportions within…

Machine Learning · Computer Science 2023-02-22 Ryoma Kobayashi , Yusuke Mukuta , Tatsuya Harada

The level of PD-L1 expression in immunohistochemistry (IHC) assays is a key biomarker for the identification of Non-Small-Cell-Lung-Cancer (NSCLC) patients that may respond to anti PD-1/PD-L1 treatments. The quantification of PD-L1…

Computer Vision and Pattern Recognition · Computer Science 2018-12-03 Ansh Kapil , Armin Meier , Aleksandra Zuraw , Keith Steele , Marlon Rebelatto , Günter Schmidt , Nicolas Brieu

Learning with label proportions (LLP), which is a learning task that only provides unlabeled data in bags and each bag's label proportion, has widespread successful applications in practice. However, most of the existing LLP methods don't…

Machine Learning · Computer Science 2019-08-20 Yanshan Xiao , HuaiPei Wang , Bo Liu

Neural networks trained on real-world datasets with long-tailed label distributions are biased towards frequent classes and perform poorly on infrequent classes. The imbalance in the ratio of positive and negative samples for each class…

Computer Vision and Pattern Recognition · Computer Science 2021-05-25 Kevin Duarte , Yogesh S. Rawat , Mubarak Shah

Learning from Label Proportions (LLP) is a weakly supervised problem in which the training data comprise bags, that is, groups of instances, each annotated only with bag-level class label proportions, and the objective is to learn a…

Machine Learning · Computer Science 2026-03-24 Tianhao Ma , Ximing Li , Changchun Li , Renchu Guan

Learning from label proportions (LLP) is a generalization of supervised learning in which the training data is available as sets or bags of feature-vectors (instances) along with the average instance-label of each bag. The goal is to train…

Machine Learning · Computer Science 2023-10-17 Anand Brahmbhatt , Rishi Saket , Aravindan Raghuveer

This paper proposes a novel and efficient method for Learning from Label Proportions (LLP), whose goal is to train a classifier only by using the class label proportions of instance sets, called bags. We propose a novel LLP method based on…

Computer Vision and Pattern Recognition · Computer Science 2023-02-20 Shinnosuke Matsuo , Ryoma Bise , Seiichi Uchida , Daiki Suehiro

Learning with Label Proportions (LLP) is the problem of recovering the underlying true labels given a dataset when the data is presented in the form of bags. This paradigm is particularly suitable in contexts where providing individual…

Machine Learning · Computer Science 2018-10-25 Rafael Poyiadzi , Raul Santos-Rodriguez , Niall Twomey

Learning from label proportions (LLP) is a weakly supervised classification problem where data points are grouped into bags, and the label proportions within each bag are observed instead of the instance-level labels. The task is to learn a…

Machine Learning · Computer Science 2023-09-26 Jianxin Zhang , Yutong Wang , Clayton Scott

Specific and effective breast cancer therapy relies on the accurate quantification of PD-L1 positivity in tumors, which appears in the form of brown stainings in high resolution whole slide images (WSIs). However, the retrieval and…

Computational Engineering, Finance, and Science · Computer Science 2024-04-17 Giacomo Cignoni , Cristian Scatena , Chiara Frascarelli , Nicola Fusco , Antonio Giuseppe Naccarato , Giuseppe Nicoló Fanelli , Alina Sîrbu

Learning from Label Proportions (LLP) is a learning setting, where the training data is provided in groups, or "bags", and only the proportion of each class in each bag is known. The task is to learn a model to predict the class labels of…

Machine Learning · Statistics 2015-02-13 Felix X. Yu , Krzysztof Choromanski , Sanjiv Kumar , Tony Jebara , Shih-Fu Chang

Learning from label proportions (LLP) is a kind of weakly supervised learning that trains an instance-level classifier from label proportions of bags, which consist of sets of instances without using instance labels. A challenge in LLP…

Machine Learning · Computer Science 2024-08-27 Shunsuke Kubo , Shinnosuke Matsuo , Daiki Suehiro , Kazuhiro Terada , Hiroaki Ito , Akihiko Yoshizawa , Ryoma Bise

We propose an end-to-end deep learning method that learns to estimate emphysema extent from proportions of the diseased tissue. These proportions were visually estimated by experts using a standard grading system, in which grades correspond…

Computer Vision and Pattern Recognition · Computer Science 2018-07-24 Gerda Bortsova , Florian Dubost , Silas Ørting , Ioannis Katramados , Laurens Hogeweg , Laura Thomsen , Mathilde Wille , Marleen de Bruijne

Accurate assessment of PD-L1 expression is critical for guiding immunotherapy, yet current immunohistochemistry (IHC) based methods are resource-intensive. We present nnUNet-B: a Bayesian segmentation framework that infers PD-L1 expression…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Roman Kinakh , Gonzalo R. Ríos-Muñoz , Arrate Muñoz-Barrutia

In the problem of learning with label proportions, which we call LLP learning, the training data is unlabeled, and only the proportions of examples receiving each label are given. The goal is to learn a hypothesis that predicts the…

Machine Learning · Computer Science 2020-04-08 Benjamin Fish , Lev Reyzin

Learning from label proportions (LLP) is a promising weakly supervised learning problem. In LLP, a set of instances (bag) has label proportions, but no instance-level labels are given. LLP aims to train an instance-level classifier by using…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Takanori Asanomi , Shinnosuke Matsuo , Daiki Suehiro , Ryoma Bise

Partial-label learning is a popular weakly supervised learning setting that allows each training example to be annotated with a set of candidate labels. Previous studies on partial-label learning only focused on the classification setting…

Machine Learning · Computer Science 2023-06-16 Xin Cheng , Deng-Bao Wang , Lei Feng , Min-Ling Zhang , Bo An

In this paper, we present a new statistical approach to automatically identify cancer regions in pathological images. The proposed method is built from statistical theory in line with evidence-based medicine. The two core technologies are…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Toshiki Kindo
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