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One of the grand challenges in intensity-modulated radiotherapy (IMRT) planning is to optimize the beam angles in a reasonable computation time. To demonstrate the value of prior knowledge on improving the efficiency of beam angle…

Medical Physics · Physics 2018-11-06 Yong-Jie Li

Any process in which competing solutions replicate with errors and numbers of their copies depend on their respective fitnesses is the evolutionary optimization process. As during carcinogenesis mutated genomes replicate according to their…

Populations and Evolution · Quantitative Biology 2009-12-15 B. Brutovsky , D. Horvath

Objective. As proton arc therapy (PAT) approaches clinical implementation, optimizing treatment plans for this innovative delivery modality remains challenging, especially in addressing arc delivery time. Existing algorithms for minimizing…

Medical Physics · Physics 2024-10-11 S. Wuyckens , G. Janssens , M. Chocan Vera , J. Sundstrom , D. Di Perri , E. Sterpin , K. Souris , J. A. Lee

This paper proposes an efficient and probabilistic adaptive voxel mapping method for LiDAR odometry. The map is a collection of voxels; each contains one plane (or edge) feature that enables the probabilistic representation of the…

Robotics · Computer Science 2022-07-11 Chongjian Yuan , Wei xu , Xiyuan Liu , Xiaoping Hong , Fu Zhang

Leveraging Large Language Models (LLMs) for recommendation has recently garnered considerable attention, where fine-tuning plays a key role in LLMs' adaptation. However, the cost of fine-tuning LLMs on rapidly expanding recommendation data…

Information Retrieval · Computer Science 2024-06-05 Xinyu Lin , Wenjie Wang , Yongqi Li , Shuo Yang , Fuli Feng , Yinwei Wei , Tat-Seng Chua

Treatment planning uncertainties are typically managed using margin-based or robust optimization. Margin-based methods expand the clinical target volume (CTV) to a planning target volume, generally unsuited for proton therapy. Robust…

Balancing influential covariates is crucial for valid treatment comparisons in clinical studies. While covariate-adaptive randomization is commonly used to achieve balance, its performance can be inadequate when the number of baseline…

Methodology · Statistics 2024-12-30 Ziqing Guo , Yang Liu , Lucy Xia

Tumor segmentation in CT scans is key for diagnosis, surgery, and prognosis, yet segmentation masks are scarce because their creation requires time and expertise. Public abdominal CT datasets have from dozens to a couple thousand tumor…

Image and Video Processing · Electrical Eng. & Systems 2025-07-09 Pedro R. A. S. Bassi , Wenxuan Li , Jieneng Chen , Zheren Zhu , Tianyu Lin , Sergio Decherchi , Andrea Cavalli , Kang Wang , Yang Yang , Alan L. Yuille , Zongwei Zhou

Sparse-voxel rasterization is a fast, differentiable alternative for optimization-based scene reconstruction, but it tends to underfit low-frequency content, depends on brittle pruning heuristics, and can overgrow in ways that inflate VRAM.…

Computer Vision and Pattern Recognition · Computer Science 2025-11-05 Jee Won Lee , Jongseong Brad Choi

Optimization-based solvers play a central role in a wide range of signal processing and communication tasks. However, their applicability in latency-sensitive systems is limited by the sequential nature of iterative methods and the high…

Signal Processing · Electrical Eng. & Systems 2026-03-12 Dvir Avrahami , Amit Milstein , Caroline Chaux , Tirza Routtenberg , Nir Shlezinger

Our understanding of organs at risk is progressing to include physical small tissues such as coronary arteries and the radiosensitivities of many small organs and tissues are high. Therefore, the accurate segmentation of small volumes in…

Image and Video Processing · Electrical Eng. & Systems 2024-04-08 Jianxin Zhou , Kadishe Fejza , Massimiliano Salvatori , Daniele Della Latta , Gregory M. Hermann , Angela Di Fulvio

High-energy, large-scale particle colliders in nuclear and high-energy physics generate data at extraordinary rates, reaching up to $1$ terabyte and several petabytes per second, respectively. The development of real-time, high-throughput…

Artificial Intelligence · Computer Science 2024-12-03 Xihaier Luo , Samuel Lurvey , Yi Huang , Yihui Ren , Jin Huang , Byung-Jun Yoon

A key question in many low-rank problems throughout optimization, machine learning, and statistics is to characterize the convex hulls of simple low-rank sets and judiciously apply these convex hulls to obtain strong yet computationally…

Optimization and Control · Mathematics 2025-03-24 Dimitris Bertsimas , Ryan Cory-Wright , Jean Pauphilet

In this first paper of a two-paper series, we present a method for optimizing the dynamic delivery of fluence maps in radiation therapy. For a given fluence map and a given delivery time, the optimization of the leaf trajectories of a…

Medical Physics · Physics 2016-08-10 David Craft , Marleen Balvert

Autonomous robots for gathering information on objects of interest has numerous real-world applications because of they improve efficiency, performance and safety. Realizing autonomy demands online planning algorithms to solve sequential…

Robotics · Computer Science 2024-05-07 Joshua Chesser , Thuraiappah Sathyan , Damith C. Ranasinghe

We consider the optimal value of information (VoI) problem, where the goal is to sequentially select a set of tests with a minimal cost, so that one can efficiently make the best decision based on the observed outcomes. Existing algorithms…

Artificial Intelligence · Computer Science 2017-07-18 Yuxin Chen , Jean-Michel Renders , Morteza Haghir Chehreghani , Andreas Krause

This paper presents a method based on a kernel dictionary learning algorithm for segmenting brain tumor regions in magnetic resonance images (MRI). A set of first-order and second-order statistical feature vectors are extracted from patches…

Computer Vision and Pattern Recognition · Computer Science 2023-10-18 Seyedeh Mahya Mousavi , Mohammad Mostafavi

Large-scale supervised classification algorithms, especially those based on deep convolutional neural networks (DCNNs), require vast amounts of training data to achieve state-of-the-art performance. Decreasing this data requirement would…

Computer Vision and Pattern Recognition · Computer Science 2016-06-15 Maya Kabkab , Azadeh Alavi , Rama Chellappa

Subsampling is a widely used and effective approach for addressing the computational challenges posed by massive datasets. Substantial progress has been made in developing non-uniform, probability-based subsampling schemes that prioritize…

Methodology · Statistics 2026-05-07 Dingyi Wang , Haiying Wang , Qingpei Hu

Motivation: Gene selection has become a common task in most gene expression studies. The objective of such research is often to identify the smallest possible set of genes that can still achieve good predictive performance. The problem of…