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Related papers: Digital Twin Generators for Disease Modeling

200 papers

A digital twin is a virtual replica of a real-world physical phenomena that uses mathematical modeling to characterize and simulate its defining features. By constructing digital twins for disease processes, we can perform in-silico…

Machine Learning · Computer Science 2024-11-04 Keying Kuang , Frances Dean , Jack B. Jedlicki , David Ouyang , Anthony Philippakis , David Sontag , Ahmed M. Alaa

Digital twins (DTs) can enable precision healthcare by continually learning a mathematical representation of patient-specific dynamics. However, mission critical healthcare applications require fast, resource-efficient DT learning, which is…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-23 Bin Xu , Ayan Banerjee , Midhat Urooj , Sandeep K. S. Gupta

A human body digital twin (DT) is a virtual representation of an individual's physiological state, created using real-time data from sensors and medical test devices, with the purpose of simulating, predicting, and optimizing health…

Artificial Intelligence · Computer Science 2024-04-24 Chenyu Tang , Wentian Yi , Edoardo Occhipinti , Yanning Dai , Shuo Gao , Luigi G. Occhipinti

Digital twins, as precise digital representations of physical systems, have evolved from passive simulation tools into intelligent and autonomous entities through the integration of artificial intelligence technologies. This paper presents…

Digital Twins (DTs) are computational models that simulate the states and temporal dynamics of real-world systems, playing a crucial role in prediction, understanding, and decision-making across diverse domains. However, existing approaches…

Machine Learning · Computer Science 2024-11-01 Samuel Holt , Tennison Liu , Mihaela van der Schaar

Artificial Intelligence (AI) and Large Language Models (LLMs) hold significant promise in revolutionizing healthcare, especially in clinical applications. Simultaneously, Digital Twin technology, which models and simulates complex systems,…

Artificial Intelligence · Computer Science 2024-09-27 Himanshu Pandey , Akhil Amod , Shivang , Kshitij Jaggi , Ruchi Garg , Abheet Jain , Vinayak Tantia

The vision of personalized medicine is to identify interventions that maintain or restore a person's health based on their individual biology. Medical digital twins, computational models that integrate a wide range of health-related data…

Quantitative Methods · Quantitative Biology 2025-10-21 Luis L. Fonseca , Lucas Böttcher , Borna Mehrad , Reinhard C. Laubenbacher

We articulate the design imperatives for machine-learning based digital twins for nonlinear dynamical systems subject to external driving, which can be used to monitor the ``health'' of the target system and anticipate its future collapse.…

Adaptation and Self-Organizing Systems · Physics 2022-10-13 Ling-Wei Kong , Yang Weng , Bryan Glaz , Mulugeta Haile , Ying-Cheng Lai

This work is interested in digital twins, and the development of a simplified framework for them, in the context of dynamical systems. Digital twin is an ingenious concept that helps on organizing different areas of expertise aiming at…

Signal Processing · Electrical Eng. & Systems 2021-01-29 TG Ritto , FA Rochinha

This paper presents a proof-of-concept digital twin framework for simulation-driven diabetes modeling using benchmark clinical data, synthetic temporal augmentation, and illustrative continuous glucose monitoring (CGM) analysis. Unlike…

Machine Learning · Computer Science 2026-05-13 Zarrin Monirzadeh

Digital Twins (DTs) are virtual representations of physical systems synchronized in real time through Internet of Things (IoT) sensors and computational models. In industrial applications, DTs enable predictive maintenance, fault diagnosis,…

Other Computer Science · Computer Science 2025-07-18 Ali Mohammad-Djafari

The digital twin concept represents an appealing opportunity to advance condition-based and predictive maintenance paradigms for civil engineering systems, thus allowing reduced lifecycle costs, increased system safety, and increased system…

Numerical Analysis · Mathematics 2023-11-10 Matteo Torzoni , Marco Tezzele , Stefano Mariani , Andrea Manzoni , Karen E. Willcox

This article presents a vision where \textit{real-time} digital twins of the physical wireless environments are continuously updated using multi-modal sensing data from the distributed infrastructure and user devices, and are used to make…

Signal Processing · Electrical Eng. & Systems 2023-01-27 Ahmed Alkhateeb , Shuaifeng Jiang , Gouranga Charan

Foundation models are trained on a large amount of data to learn generic patterns. Consequently, these models can be used and fine-tuned for various purposes. Naturally, studying such models' use in the context of digital twins for…

Software Engineering · Computer Science 2025-07-03 Shaukat Ali , Paolo Arcaini , Aitor Arrieta

The biopharmaceutical industry is increasingly developing digital twins to digitalize and automate the manufacturing process in response to the growing market demands. However, this shift presents significant challenges for human operators,…

Human-Computer Interaction · Computer Science 2025-04-02 Mohammed Aatif Shahab , Francesco Destro , Richard D. Braatz

Deep learning models have created great opportunities for data-driven fault diagnosis but they require large amount of labeled failure data for training. In this paper, we propose to use a digital twin to support developing data-driven…

Machine Learning · Computer Science 2024-11-05 Killian Mc Court , Xavier Mc Court , Shijia Du , Zhiguo Zeng

Digital twin, which enables emulation, evaluation, and optimization of physical entities through synchronized digital replicas, has gained increasing attention as a promising technology for intricate wireless networks. For 6G, numerous…

Networking and Internet Architecture · Computer Science 2024-08-12 Zhenyu Tao , Wei Xu , Yongming Huang , Xiaoyun Wang , Xiaohu You

Digital twin (DT) enables smart manufacturing by leveraging real-time data, AI models, and intelligent control systems. This paper presents a state-of-the-art analysis on the emerging field of DTs in the context of milling. The critical…

Systems and Control · Electrical Eng. & Systems 2025-12-16 Wenyi Liu , R. Sharma , W. "Grace" Guo , J. Yi , Y. B. Guo

Digital network twins (DNTs), by representing a physical network using a virtual model, offer significant benefits such as streamlined network development, enhanced productivity, and cost reduction for next-generation (nextG) communication…

Networking and Internet Architecture · Computer Science 2025-09-04 Zifan Zhang , Zhiyuan Peng , Hanzhi Yu , Mingzhe Chen , Yuchen Liu

A digital twin can be defined as an adaptive model of a complex physical system. Recent advances in computational pipelines, multiphysics solvers, artificial intelligence, big data cybernetics, data processing and management tools bring the…

Signal Processing · Electrical Eng. & Systems 2019-10-07 Adil Rasheed , Omer San , Trond Kvamsdal