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The transformation to Industry 4.0 also transforms the processes of how we develop intelligent manufacturing production systems. To advance the software development of these new (embedded) software systems, digital twins may be employed.…

Software Engineering · Computer Science 2024-05-30 Alexander Barbie , Wilhelm Hasselbring

Digital twin technology has significant promise, relevance and potential of widespread applicability in various industrial sectors such as aerospace, infrastructure and automotive. However, the adoption of this technology has been slower…

Machine Learning · Statistics 2020-06-16 Souvik Chakraborty , Sondipon Adhikari , Ranjan Ganguli

Medical Cyber-Physical Systems (CPSs) integrating Patients, Devices, and healthcare personnel (Physicians) form safety-critical PDP triads whose dependability is challenged by system heterogeneity and uncertainty in human and physiological…

Software Engineering · Computer Science 2026-02-25 Bruno Guindani , Matteo Camilli , Livia Lestingi , Marcello M. Bersani

Healthcare artificial intelligence systems often degrade in performance when deployed across institutions, with documented performance drops and perpetuation of discriminatory patterns embedded in data. This brittleness comes, in part, from…

Machine Learning · Computer Science 2026-03-30 Munib Mesinovic , Max Buhlan , Tingting Zhu

A new network named the "Digital Twin Network" (DTN) uses the "Digital Twin" (DT) technology to produce virtual twins of real things. The network load and size continue to grow as a result of the development of 5G, the Internet of Things,…

Networking and Internet Architecture · Computer Science 2023-12-27 Abubakar Isah , Hyeju Shin , Ibrahim Aliyu , Sangwon Oh , Sangjoon Lee , Jaehyung Park , Minsoo Hahn , Jinsul Kim

A Digital Twin (DT) is a virtual replica of a physical object or system, created to monitor, analyze, and optimize its behavior and characteristics. A Spatial Digital Twin (SDT) is a specific type of digital twin that emphasizes the…

Computers and Society · Computer Science 2023-06-13 Mohammed Eunus Ali , Muhammad Aamir Cheema , Tanzima Hashem , Anwaar Ulhaq , Muhammad Ali Babar

Alzheimer's Disease (AD) is a neurodegenerative disease that affects subjects in a broad range of severity and is assessed in clinical trials with multiple cognitive and functional instruments. As clinical trials in AD increasingly focus on…

The concept of the Digital Twin, which in the context of this paper is the virtual representation of a production system or its components, can be used as a "digital playground" to master the increasing complexity of these assets. One of…

Computational Engineering, Finance, and Science · Computer Science 2024-10-15 Daniel Dittler , Valentin Stegmaier , Nasser Jazdi , Michael Weyrich

Internet of Everything (IoE) applications such as haptics, human-computer interaction, and extended reality, using the sixth-generation (6G) of wireless systems have diverse requirements in terms of latency, reliability, data rate, and…

Networking and Internet Architecture · Computer Science 2024-10-28 Latif U. Khan , Walid Saad , Dusit Niyato , Zhu Han , Choong Seon Hong

Digital Twin technology creates virtual replicas of physical objects, processes, or systems by replicating their properties, data, and behaviors. This advanced technology offers a range of intelligent functionalities, such as modeling,…

Machine Learning · Computer Science 2024-08-26 Sagar Srinivas Sakhinana , Krishna Sai Sudhir Aripirala , Shivam Gupta , Venkataramana Runkana

Current neural interfaces such as brain-computer interfaces (BCIs) face several fundamental challenges, including frequent recalibration due to neuroplasticity and session-to-session variability, real-time processing latency, limited…

Human-Computer Interaction · Computer Science 2026-01-06 Mohammad Mahdi Habibi Bina , Sepideh Baghernezhad , Mohammad Reza Daliri , Mohammad Hassan Moradi

Digital twins are emerging as a valuable tool for short-term decision-making as well as for long-term strategic planning across numerous domains, including process industry, energy, space, transport, and healthcare. This paper reports on…

Artificial Intelligence · Computer Science 2025-05-13 Riccardo Sieve , Paul Kobialka , Laura Slaughter , Rudolf Schlatte , Einar Broch Johnsen , Silvia Lizeth Tapia Tarifa

The population of older adults is steadily increasing, with a strong preference for aging-in-place rather than moving to care facilities. Consequently, supporting this growing demographic has become a significant global challenge. However,…

Computers and Society · Computer Science 2025-04-08 Yongjie Wang , Jonathan Cyril Leung , Ming Chen , Zhiwei Zeng , Benny Toh Hsiang Tan , Yang Qiu , Zhiqi Shen

Digital twin has recently attracted growing attention, leading to intensive research and applications. Along with this, a new research area, dubbed as "human digital twin" (HDT), has emerged. Similar to the conception of digital twin, HDT…

Human-Computer Interaction · Computer Science 2022-12-13 Yujia Lin , Liming Chen , Aftab Ali , Christopher Nugent , Cleland Ian , Rongyang Li , Dazhi Gao , Hang Wang , Yajie Wang , Huansheng Ning

Automated driving systems are an integral part of the automotive industry. Tools such as Robot Operating System and simulators support their development. However, in the end, the developers must test their algorithms on a real vehicle. To…

Robotics · Computer Science 2024-12-17 Jiri Vlasak , Jaroslav Klapálek , Adam Kollarčík , Michal Sojka , Zdeněk Hanzálek

The concept of a digital twin has exploded in popularity over the past decade, yet confusion around its plurality of definitions, its novelty as a new technology, and its practical applicability still exists, all despite numerous reviews,…

Machine Learning · Computer Science 2022-06-27 Brian Kunzer , Mario Berges , Artur Dubrawski

A Digital Twin (DT) is a simulation of a physical system that provides information to make decisions that add economic, social or commercial value. The behaviour of a physical system changes over time, a DT must therefore be continually…

Machine Learning · Computer Science 2023-01-04 Felipe Montana , Adam Hartwell , Will Jacobs , Visakan Kadirkamanathan , Andrew R Mills , Tom Clark

Personalized chronic care requires the integration of multimodal health data to enable precise, adaptive, and preventive decision-making. Yet most current digital twin (DT) applications remain organ-specific or tied to isolated data types,…

Software Engineering · Computer Science 2025-10-13 Amal Elgammal , Bernd J. Krämer , Michael P. Papazoglou , Mira Raheem

This paper investigates the transformative potential of digital twin (DT) technology for non-terrestrial networks (NTNs). NTNs, comprising airborne and space-borne elements, face unique challenges in network control, management, and…

Networking and Internet Architecture · Computer Science 2024-11-20 Hayder Al-Hraishawi , Madyan Alsenwi , Junaid ur Rehman , Eva Lagunas , Symeon Chatzinotas

The proliferation of emergent network applications (e.g., AR/VR, telesurgery, real-time communications) is increasing the difficulty of managing modern communication networks. These applications typically have stringent requirements (e.g.,…

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