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Large language models (LLMs) open up new horizons for sequential recommendations, owing to their remarkable language comprehension and generation capabilities. However, there are still numerous challenges that should be addressed to…

Information Retrieval · Computer Science 2024-03-29 Yuling Wang , Changxin Tian , Binbin Hu , Yanhua Yu , Ziqi Liu , Zhiqiang Zhang , Jun Zhou , Liang Pang , Xiao Wang

Agentic systems enable the intelligent use of research tooling, augmenting a researcher's ability to investigate and propose novel solutions to existing problems. Within Additive Manufacturing (AM), alloy selection and evaluation remains a…

Artificial Intelligence · Computer Science 2026-01-27 Peter Pak , Achuth Chandrasekhar , Amir Barati Farimani

The large language model (LLM) has achieved significant success across various domains. However, the inherent complexity of causal problems and causal theory poses challenges in accurately describing them in natural language, making it…

Artificial Intelligence · Computer Science 2025-10-15 Kairong Han , Kun Kuang , Ziyu Zhao , Junjian Ye , Fei Wu

Estimating treatment effects (TE) from observational data is a critical yet complex task in many fields, from healthcare and economics to public policy. While recent advances in machine learning and causal inference have produced powerful…

Machine Learning · Computer Science 2025-08-15 Jeroen Berrevoets , Julianna Piskorz , Robert Davis , Harry Amad , Jim Weatherall , Mihaela van der Schaar

Large language models (LLMs) have achieved remarkable performance on diverse benchmarks, yet existing evaluation practices largely rely on coarse summary metrics that obscure underlying reasoning abilities. In this work, we propose novel…

Methodology · Statistics 2026-03-17 Jia Liu , Zhiyu Xu , Yuqi Gu

Large language models (LLMs) integrated with autonomous agents hold significant potential for advancing scientific discovery through automated reasoning and task execution. However, applying LLM agents to drug discovery is still constrained…

Artificial Intelligence · Computer Science 2025-07-29 Kun Li , Zhennan Wu , Shoupeng Wang , Jia Wu , Shirui Pan , Wenbin Hu

What research can be pursued with small models trained to complete true programs? Typically, researchers study program synthesis via large language models (LLMs) which introduce issues such as knowing what is in or out of distribution,…

Artificial Intelligence · Computer Science 2026-02-11 Russ Webb , Jason Ramapuram

Atomistic simulations are essential tools in chemistry and materials science, accelerating the discovery of novel catalysts, energy storage materials, and pharmaceuticals. However, running these simulations remains challenging due to the…

Chemical Physics · Physics 2025-06-11 Thang D. Pham , Aditya Tanikanti , Murat Keçeli

In this paper, we consider the process of transforming causal domain knowledge into a representation that aligns more closely with guidelines from causal data science. To this end, we introduce two novel tasks related to distilling causal…

Computation and Language · Computer Science 2024-11-26 Houssam Razouk , Leonie Benischke , Georg Niess , Roman Kern

Large Language Models (LLMs) like GPT-4 have revolutionized natural language processing, showing remarkable linguistic proficiency and reasoning capabilities. However, their application in strategic multi-agent decision-making environments…

Computation and Language · Computer Science 2024-05-29 Chuanhao Li , Runhan Yang , Tiankai Li , Milad Bafarassat , Kourosh Sharifi , Dirk Bergemann , Zhuoran Yang

Large language models (LLMs) have dramatically enhanced the field of language intelligence, as demonstrably evidenced by their formidable empirical performance across a spectrum of complex reasoning tasks. Additionally, theoretical proofs…

Computation and Language · Computer Science 2023-11-21 Zhuosheng Zhang , Yao Yao , Aston Zhang , Xiangru Tang , Xinbei Ma , Zhiwei He , Yiming Wang , Mark Gerstein , Rui Wang , Gongshen Liu , Hai Zhao

Large language models (LLMs) are playing an increasingly important role in science and engineering. For example, their ability to parse and understand human and computer languages makes them powerful interpreters and their use in…

Materials Science · Physics 2023-10-19 Juan C. Verduzco , Ethan Holbrook , Alejandro Strachan

Deductive coding is a widely used qualitative research method for determining the prevalence of themes across documents. While useful, deductive coding is often burdensome and time consuming since it requires researchers to read, interpret,…

Computation and Language · Computer Science 2023-06-28 Robert Chew , John Bollenbacher , Michael Wenger , Jessica Speer , Annice Kim

Large language model (LLM) agents have demonstrated impressive capabilities in utilizing external tools and knowledge to boost accuracy and reduce hallucinations. However, developing prompting techniques that enable LLM agents to…

Multi-agent systems (MAS) extend large language models (LLMs) from independent single-model reasoning to coordinative system-level intelligence. While existing LLM agents depend on text-based mediation for reasoning and communication, we…

Computation and Language · Computer Science 2025-12-09 Jiaru Zou , Xiyuan Yang , Ruizhong Qiu , Gaotang Li , Katherine Tieu , Pan Lu , Ke Shen , Hanghang Tong , Yejin Choi , Jingrui He , James Zou , Mengdi Wang , Ling Yang

Large Language Models (LLMs) have shown promising potential in the medical domain, assisting with tasks like clinical note generation and patient communication. However, current LLMs are limited to text-based communication, hindering their…

Computation and Language · Computer Science 2025-06-17 Yusheng Liao , Shuyang Jiang , Yanfeng Wang , Yu Wang

This work presents an ontology-integrated large language model (LLM) framework for chemical engineering that unites structured domain knowledge with generative reasoning. The proposed pipeline aligns model training and inference with the…

Machine Learning · Computer Science 2025-12-15 Crystal Su , Kuai Yu , Jingrui Zhang , Mingyuan Shao , Daniel Bauer

Large Language Models (LLMs) have the potential to accelerate small molecule drug design due to their ability to reason about information from diverse sources and formats. However, their practical utility remains unclear due to the lack of…

The discovery of new catalysts is essential for the design of new and more efficient chemical processes in order to transition to a sustainable future. We introduce an AI-guided computational screening framework unifying linguistic…

Large language models (LLMs) often exhibit performance disparities across languages, with naive multilingual fine-tuning frequently degrading performance due to negative cross-lingual interference. To address this, we introduce COMPASS…

Machine Learning · Computer Science 2026-04-23 Noah Flynn