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Here, we introduce a novel framework for modelling the spatiotemporal dynamics of disease spread known as conditional logistic individual-level models (CL-ILM's). This framework alleviates much of the computational burden associated with…

Computation · Statistics 2024-09-05 Tahmina Akter , Rob Deardon

Spatial individual-level models (ILMs) provide a flexible framework for modelling infectious disease transmission across populations with known locations. Bayesian inference for these models relies on Markov chain Monte Carlo (MCMC), which…

Computation · Statistics 2026-05-29 Yicheng Mao , Rob Deardon

Infectious disease models can be of great use for understanding the underlying mechanisms that influence the spread of diseases and predicting future disease progression. Modeling has been increasingly used to evaluate the potential impact…

Applications · Statistics 2019-08-20 Md Mahsin , Rob Deardon , Patrick Brown

During epidemics, people will often modify their behaviour patterns over time in response to changes in their perceived risk of spreading or contracting the disease. This can substantially impact the trajectory of the epidemic. However,…

Methodology · Statistics 2023-08-03 Madeline A. Ward , Rob Deardon , Lorna E. Deeth

Infectious diseases have severe health and economic consequences for society. It is important in controlling the spread of an emerging infectious disease to be able to both estimate the parameters of the underlying model and identify those…

Computation · Statistics 2019-09-26 Jessica Welding , Peter Neal

In this article, we introduce the R package EpiILM, which provides tools for simulation from, and inference for, discrete-time individual-level models of infectious disease transmission proposed by Deardon et al. (2010). The inference is…

Applications · Statistics 2020-04-02 Vineetha Warriyar K. V. , Waleed Almutiry , Rob Deardon

One of the most important issues in the critical assessment of spatio-temporal stochastic models for epidemics is the selection of the transmission kernel used to represent the relationship between infectious challenge and spatial…

Applications · Statistics 2019-11-06 David Thong , George Streftaris , Gavin J. Gibson

The ongoing COVID-19 pandemic calls for a multi-faceted public health response comprising complementary interventions to control the spread of the disease while vaccines and therapies are developed. Many of these interventions need to be…

Applications · Statistics 2020-08-24 Andres Colubri , Kailash Yadav , Abhishek Jha , Pardis C. Sabeti

The primary tool for predicting infectious disease spread and intervention effectiveness is the mass action Susceptible-Infected-Recovered model of Kermack and McKendrick. Its usefulness derives largely from its conceptual and mathematical…

Populations and Evolution · Quantitative Biology 2015-09-03 Joel C. Miller , Anja C. Slim , Erik M. Volz

Statistical models used to estimate the spatio-temporal pattern in disease risk from areal unit data represent the risk surface for each time period with known covariates and a set of spatially smooth random effects. The latter act as a…

Applications · Statistics 2016-04-19 Alastair Rushworth , Duncan Lee , Christophe Sarran

Spatial connectivity is an important consideration when modelling infectious disease data across a geographical region. Connectivity can arise for many reasons, including shared characteristics between regions, and human or vector movement.…

Methodology · Statistics 2022-06-06 Sophie A Lee , Theodoros Economou , Rachel Lowe

This paper describes the R package EpiILMCT, which allows users to study the spread of infectious disease using continuous time individual level models (ILMs). The package provides tools for simulation from continuous time ILMs that are…

Applications · Statistics 2021-08-17 Waleed Almutiry , Vineetha Warriyar K , Rob Deardon

Increasing rates of global trade and travel, as well as changing climatic patterns, have led to more frequent outbreaks of plant disease epidemics worldwide. Mathematical modelling is a key tool in predicting where and how these new threats…

Populations and Evolution · Quantitative Biology 2019-11-28 Frédéric Fabre , Jérôme Coville , Nik J. Cunniffe

Individual-level epidemic models are increasingly being used to help understand the transmission dynamics of various infectious diseases. However, fitting such models to individual-level epidemic data is challenging, as we often only know…

Applications · Statistics 2026-02-17 Dirk Douwes-Schultz , Rob Deardon , Alexandra M. Schmidt

The Bayesian analysis of infectious disease surveillance data from multiple locations typically involves building and fitting a spatio-temporal model of how the disease spreads in the structured population. Here we present new generally…

Methodology · Statistics 2025-03-04 Matthew Adeoye , Xavier Didelot , Simon EF Spencer

Besides mimicking bio-chemical and multi-scale communication mechanisms, molecular communication forms a theoretical framework for virus infection processes. Towards this goal, aerosol and droplet transmission has recently been modeled as a…

Information Theory · Computer Science 2021-01-29 Peter Adam Hoeher , Martin Damrath , Sunasheer Bhattacharjee , Max Schurwanz

We propose a framework for Bayesian non-parametric estimation of the rate at which new infections occur assuming that the epidemic is partially observed. The developed methodology relies on modelling the rate at which new infections occur…

Methodology · Statistics 2014-12-16 Edward S. Knock , Theodore Kypraios

We introduce Pathogen.jl for simulation and inference of transmission network individual level models (TN-ILMs) of infectious disease spread in continuous time. TN-ILMs can be used to jointly infer transmission networks, event times, and…

Applications · Statistics 2021-08-27 Justin Angevaare , Zeny Feng , Rob Deardon

Motivated by foot-and-mouth disease (FMD) outbreak data from Turkey, we develop a model to estimate disease risk based on a space-time record of outbreaks. The spread of infectious disease in geographical units depends on both transmission…

Applications · Statistics 2021-10-19 Xiaoxiao Li , Matthew Ferrari , Michael J. Tildesley , Murali Haran

Emerging marine infectious diseases pose a substantial threat to marine ecosystems and the conservation of their biodiversity. Compartmental models of epidemic transmission in marine sessile organisms, available only recently, are based on…

Populations and Evolution · Quantitative Biology 2022-11-03 Àlex Giménez-Romero , Federico Vazquez , Cristóbal López , Manuel A. Matías
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