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A novel framework for designing the molecular structure of chemical compounds with a desired chemical property has recently been proposed. The framework infers a desired chemical graph by solving a mixed integer linear program (MILP) that…

Computational Engineering, Finance, and Science · Computer Science 2023-05-02 Jianshen Zhu , Naveed Ahmed Azam , Kazuya Haraguchi , Liang Zhao , Hiroshi Nagamochi , Tatsuya Akutsu

Complex nanophotonic structures hold the potential to deliver exquisitely tailored optical responses for a range of applications. Metal-insulator-metal (MIM) metasurfaces arranged in supercells, for instance, can be tailored by geometry and…

The escalating threat of adversarial attacks on deep learning models, particularly in security-critical fields, has underscored the need for robust deep learning systems. Conventional robustness evaluations have relied on adversarial…

Cryptography and Security · Computer Science 2024-11-19 Ping Guo , Cheng Gong , Xi Lin , Zhiyuan Yang , Qingfu Zhang

In real recommendation scenarios, users often have different types of behaviors, such as clicking and buying. Existing research methods show that it is possible to capture the heterogeneous interests of users through different types of…

Information Retrieval · Computer Science 2024-02-21 Weixin Li , Yuhao Wu , Yang Liu , Weike Pan , Zhong Ming

Multi-beam ptychography (MBP) offers a scalable solution to improve the throughput of state-of-the-art ptychography by increasing the number of coherent beams that illuminate the sample simultaneously. However, increasing the number of…

Optics · Physics 2025-10-29 Runqing Yang , Pablo Villanueva-Perez , Maik Kahnt

Peptide self-assembly prediction offers a powerful bottom-up strategy for designing biocompatible, low-toxicity materials for large-scale synthesis in a broad range of biomedical and energy applications. However, screening the vast sequence…

Biomolecules · Quantitative Biology 2026-04-23 Nuno Costa , Julija Zavadlav

Rapid advances in additive manufacturing over the past decade have kindled widespread interest in the rational design of metamaterials with unique properties. However, many applications require multi-physics metamaterials, where multiple…

Materials Science · Physics 2021-02-10 Sebastien J. P. Callens , Christoph H. Arns , Alina Kuliesh , Amir A. Zadpoor

The sustainable production of many bulk chemicals relies on heterogeneous catalysis. The rational design or improvement of the required catalysts critically depends on insights into the underlying mechanisms at the atomic scale. In recent…

Chemical Physics · Physics 2024-11-04 Amir Omranpour , Jan Elsner , K. Nikolas Lausch , Jörg Behler

Hyperspectral target detection (HTD) identifies objects of interest from complex backgrounds at the pixel level, playing a vital role in Earth observation. However, HTD faces challenges due to limited prior knowledge and spectral variation,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Dunbin Shen , Xuanbing Zhu , Jiacheng Tian , Jianjun Liu , Zhenrong Du , Hongyu Wang , Xiaorui Ma

Classifying hyperspectral images is a difficult task in remote sensing, due to their complex high-dimensional data. To address this challenge, we propose HSIMamba, a novel framework that uses bidirectional reversed convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Judy X Yang , Jun Zhou , Jing Wang , Hui Tian , Alan Wee Chung Liew

Antibody engineering is essential for developing therapeutics and advancing biomedical research. Traditional discovery methods often rely on time-consuming and resource-intensive experimental screening. To enhance and streamline this…

Biomolecules · Quantitative Biology 2025-07-04 Jie Gao , Jing Hu , Shanzhuo Zhang , Kunrui Zhu , Sheng Qian , Yueyang Huang , Xiaonan Zhang , Xiaomin Fang

Recent advances in multimodal learning have significantly improved cancer survival risk prediction. However, the joint prognostic potential of protein markers and histopathology images remains underexplored, largely due to the high cost and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Jing Dai , Chen Wu , Ming Wu , Qibin Zhang , Zexi Wu , Jingdong Zhang , Hongming Xu

Multi-objective optimization is a crucial matter in computer systems design space exploration because real-world applications often rely on a trade-off between several objectives. Derivatives are usually not available or impractical to…

Machine Learning · Computer Science 2019-07-26 Luigi Nardi , David Koeplinger , Kunle Olukotun

Agent-based modeling (ABM) is a bottom-up modeling approach, where each entity of the system being modeled is uniquely represented as an independent decision-making agent. Large scale emergent behavior in ABMs is population sensitive. As…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-04-12 Nuno Fachada , Vitor V. Lopes , Rui C. Martins , Agostinho C. Rosa

In the field of MLLM-based GUI agents, compared to smartphones, the PC scenario not only features a more complex interactive environment, but also involves more intricate intra- and inter-app workflows. To address these issues, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2025-02-24 Haowei Liu , Xi Zhang , Haiyang Xu , Yuyang Wanyan , Junyang Wang , Ming Yan , Ji Zhang , Chunfeng Yuan , Changsheng Xu , Weiming Hu , Fei Huang

Product distribution matching (PDM) is proposed to generate target distributions over large alphabets by combining the output of several parallel distribution matchers (DMs) with smaller output alphabets. The parallel architecture of PDM…

Information Theory · Computer Science 2017-02-27 Georg Böcherer , Patrick Schulte , Fabian Steiner

Antibiotics are a vital class of drugs closely associated with the prevention and treatment of bacterial infections. Accurate prediction of molecular antimicrobial activity remains a key challenge in the pursuit of novel antibiotic…

Quantitative Methods · Quantitative Biology 2025-09-23 R. He

Hyperdimensional Computing (HDC) is a bio-inspired computing framework that has gained increasing attention, especially as a more efficient approach to machine learning (ML). This work introduces the \name{} compiler, the first open-source…

Machine Learning · Computer Science 2023-04-26 Pere Vergés , Mike Heddes , Igor Nunes , Tony Givargis , Alexandru Nicolau

Grant-free non-orthogonal multiple access has been regarded as a viable approach to accommodate access for a massive number of machine-type devices with small data packets. The sporadic activation of the devices creates a multiuser setup…

Signal Processing · Electrical Eng. & Systems 2023-05-15 Yanna Bai , Wei Chen , Bo Ai , Petar Popovski

Antibody design is an essential yet challenging task in various domains like therapeutics and biology. There are two major defects in current learning-based methods: 1) tackling only a certain subtask of the whole antibody design pipeline,…

Biomolecules · Quantitative Biology 2023-05-31 Xiangzhe Kong , Wenbing Huang , Yang Liu
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