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The recent discovery of universal principles underlying many complex networks occurring across a wide range of length scales in the biological world has spurred physicists in trying to understand such features using techniques from…

Biological Physics · Physics 2015-05-13 Sitabhra Sinha

New checkable criteria for persistence of chemical reaction networks are proposed, which extend and complement those obtained by the authors in previous work. The new results allow the consideration of reaction rates which are time-varying,…

Molecular Networks · Quantitative Biology 2009-05-12 David Angeli , Patrick De Leenheer , Eduardo Sontag

Synchronization in networks of coupled oscillators is known to be largely determined by the spectral and symmetry properties of the interaction network. Here we leverage this relation to study a class of networks for which the threshold…

Adaptation and Self-Organizing Systems · Physics 2017-12-21 Takashi Nishikawa , Adilson E. Motter

Complex chemical reaction networks, which underlie many industrial and biological processes, often exhibit non-monotonic changes in chemical species concentrations, typically described using nonlinear models. Such non-monotonic dynamics are…

Adaptation and Self-Organizing Systems · Physics 2020-10-21 Zachary G. Nicolaou , Takashi Nishikawa , Schuyler B. Nicholson , Jason R. Green , Adilson E. Motter

Biological systems encode function not primarily in steady states, but in the structure of transient responses elicited by time-varying stimuli. Overshoots, biphasic dynamics, adaptation kinetics, fold-change detection, entrainment, and…

Quantitative Methods · Quantitative Biology 2026-01-05 Eduardo D. Sontag

Networks in nature do not act in isolation but instead exchange information, and depend on each other to function properly. An incipient theory of Networks of Networks have shown that connected random networks may very easily result in…

Observability of complex systems/networks is the focus of this paper, which is shown to be closely related to the concept of contraction. Indeed, for observable network tracking it is necessary/sufficient to have one node in each…

Systems and Control · Computer Science 2017-09-13 Mohammadreza Doostmohammadian , Hamid R. Rabiee , Houman Zarrabi , Usman Khan

Can the topology of a network that consists of many particles interacting with each other change in complexity when a phase transition occurs? The answer to this question is particularly interesting to understand the nature of phase…

Statistical Mechanics · Physics 2014-08-12 Chung-Pin Chou

We review selected results related to robustness of networked systems in finite and asymptotically large size regimes, under static and dynamical settings. In the static setting, within the framework of flow over finite networks, we discuss…

Systems and Control · Electrical Eng. & Systems 2019-09-17 Ketan Savla , Jeff S. Shamma , Munther A. Dahleh

The non-linear stress-strain relation for crosslinked polymer networks is studied using molecular dynamics simulations. Previously we demonstrated the importance of trapped entanglements in determining the elastic and relaxational…

Soft Condensed Matter · Physics 2009-10-31 Gary S. Grest , Mathias Puetz , Kurt Kremer , Ralf Everaers

Reaction networks are systems in which the populations of a finite number of species evolve through predefined interactions. Such networks are found as modeling tools in many biological disciplines such as biochemistry, ecology,…

Molecular Networks · Quantitative Biology 2015-06-15 Ankit Gupta , Corentin Briat , Mustafa Khammash

Among all characteristics exhibited by natural and man-made networks the small-world phenomenon is surely the most relevant and popular. But despite its significance, a reliable and comparable quantification of the question `how small is a…

Physics and Society · Physics 2019-11-27 Gorka Zamora-López , Romain Brasselet

In complex network-coupled dynamical systems, two questions of central importance are how to identify the most vulnerable components and how to devise a network making the overall system more robust to external perturbations. To address…

Adaptation and Self-Organizing Systems · Physics 2019-09-11 Melvyn Tyloo , Philippe Jacquod

Reaction networks are mainly used to model the time-evolution of molecules of interacting chemical species. Stochastic models are typically used when the counts of the molecules are low, whereas deterministic models are used when the counts…

Probability · Mathematics 2019-10-04 David Anderson , Daniele Cappelletti , Jinsu Kim , Tung Nguyen

We study the bar-and-joint frameworks in $\mathbb{R}^2$ such that some vertices are constrained to lie on some lines. The generic rigidity of such frameworks is characterised by Streinu and Theran (2010). Katoh and Tanigawa (2013) remarked…

Combinatorics · Mathematics 2022-12-09 Hakan Guler

It is well-known that biological and social interaction networks have a varying degree of redundancy, though a consensus of the precise cause of this is so far lacking. In this paper, we introduce a topological redundancy measure for…

In network theory, a question of prime importance is how to assess network vulnerability in a fast and reliable manner. With this issue in mind, we investigate the response to parameter changes of coupled dynamical systems on complex…

Adaptation and Self-Organizing Systems · Physics 2018-02-27 Melvyn Tyloo , Tommaso Coletta , Philippe Jacquod

This paper presents a framework based on matrices of monoids for the study of coupled cell networks. We formally prove within the proposed framework, that the set of results about invariant synchrony patterns for unweighted networks also…

Multiagent Systems · Computer Science 2022-01-13 Pedro M. Sequeira , António P. Aguiar , João Hespanha

Network translation has recently been used to establish steady state properties of mass action systems by corresponding the given system to a generalized one which is either dynamically or steady state equivalent. In this work we further…

Dynamical Systems · Mathematics 2018-08-14 Elisa Tonello , Matthew D. Johnston

Identifying and explaining the structure of complex networks at different scales has become an important problem across disciplines. At the mesoscale, modular architecture has attracted most of the attention. At the macroscale, other…

Physics and Society · Physics 2018-11-09 María J. Palazzi , Javier Borge-Holthoefer , Claudio Tessone , Albert Solé-Ribalta