English
Related papers

Related papers: Seed Selection in the Heterogeneous Moran Process

200 papers

The Moran process models the spread of genetic mutations through a population. A mutant with relative fitness $r$ is introduced into a population and the system evolves, either reaching fixation (in which every individual is a mutant) or…

Computational Engineering, Finance, and Science · Computer Science 2013-08-01 Josep Diaz , Leslie Ann Goldberg , George B. Mertzios , David Richerby , Maria Serna , Paul G. Spirakis

Resource are often not uniformly distributed within a population. Spatial variations of concentration of a resource, change the fitness of competing strategies locally. The notion of fitness varying with respect to both genotype and…

Populations and Evolution · Quantitative Biology 2022-04-08 Hossein Nemati , Mohammad Reza Ejtehadi , Kamran Kaveh

In evolutionary dynamics, the probability that a mutation spreads through the whole population, having arisen in a single individual, is known as the fixation probability. In general, it is not possible to find the fixation probability…

Populations and Evolution · Quantitative Biology 2010-10-26 Valmir C. Barbosa , Raul Donangelo , Sergio R. Souza

The paper is devoted to the study of the asymptotic behaviour of Moran process in random environment, say random selection. In finite population, the Moran process may be degenerate in finite time, thus we will study its limiting process in…

Probability · Mathematics 2019-11-05 Arnaud Guillin , Arnaud Personne , Edouard Strickler

The evolution of two species with different fitness is investigated on degree-heterogeneous graphs. The population evolves either by one individual dying and being replaced by the offspring of a random neighbor (voter model (VM) dynamics)…

Populations and Evolution · Quantitative Biology 2009-11-13 T. Antal , S. Redner , V. Sood

Natural selection and random drift are competing phenomena for explaining the evolution of populations. Combining a highly fit mutant with a population structure that improves the odds that the mutant spreads through the whole population…

Populations and Evolution · Quantitative Biology 2009-08-14 Valmir C. Barbosa , Raul Donangelo , Sergio R. Souza

We define the incentive process, a natural generalization of the Moran process incorporating evolutionary updating mechanisms corresponding to well-known evolutionary dynamics, such as the logit, projection, and best-reply dynamics.…

Dynamical Systems · Mathematics 2013-12-04 Marc Harper , Dashiell Fryer

We consider a model of a population with fixed size $N$, which is subjected to an unlimited supply of beneficial mutations at a constant rate $\mu_N$. Individuals with $k$ beneficial mutations have the fitness $(1+s_N)^k$. Each individual…

Probability · Mathematics 2024-12-30 Nantawat Udomchatpitak , Jason Schweinsberg

We consider the spatially inhomogeneous Moran model with seed-banks introduced in den Hollander and Nandan (2021). Populations comprising $active$ and $dormant$ individuals are structured in colonies labelled by $\mathbb{Z}^d,~d\geq 1$. The…

Probability · Mathematics 2023-02-23 Shubhamoy Nandan

We interpret the Moran model of natural selection and drift as an algorithm for learning features of a simplified fitness landscape, specifically genotype superiority. This algorithm's efficiency in extracting these characteristics is…

Populations and Evolution · Quantitative Biology 2023-09-25 Miles Miller-Dickson , Christopher Rose , C. Brandon Ogbunugafor , I. Saira Mian

The spread of an advantageous mutation through a population is of fundamental interest in population genetics. While the classical Moran model is formulated for a well-mixed population, it has long been recognized that in real-world…

Populations and Evolution · Quantitative Biology 2022-09-27 Jasmine Foo , Einar Bjarki Gunnarsson , Kevin Leder , David Sivakoff

Different evolutionary models are known to make disparate predictions for the success of an invading mutant in some situations. For example, some evolutionary mechanics lead to amplification of selection in structured populations, while…

Populations and Evolution · Quantitative Biology 2020-07-01 Francisco Herrerías-Azcué , Vicente Pérez-Muñuzuri , Tobias Galla

The Moran process is a foundational model of genetic drift and mutation in finite populations. In its standard two-allele form with population size $n$, allele counts, and hence allele frequencies, change through stochastic replacement and…

Populations and Evolution · Quantitative Biology 2026-01-16 Dan Braha , Marcus A. M. de Aguiar

We consider a spatial version of the classical Moran model with seed-banks where the constituent populations have finite sizes. Individuals live in colonies labelled by $\mathbb{Z}^d$, $d\geq 1$, playing the role of a geographic space,…

Probability · Mathematics 2023-02-07 Frank den Hollander , Shubhamoy Nandan

The interrelationships of the fundamental biological processes natural selection, mutation, and stochastic drift are quantified by the entropy rate of Moran processes with mutation, measuring the long-run variation of a Markov process. The…

Dynamical Systems · Mathematics 2014-01-14 Marc Harper

Resources are rarely distributed uniformly within a population. Heterogeneity in the concentration of a drug, the quality of breeding sites, or wealth can all affect evolutionary dynamics. In this study, we represent a collection of…

Populations and Evolution · Quantitative Biology 2022-02-18 Kamran Kaveh , Alex McAvoy , Krishnendu Chatterjee , Martin A. Nowak

Muller's ratchet, in its prototype version, models a haploid, asexual population whose size~$N$ is constant over the generations. Slightly deleterious mutations are acquired along the lineages at a constant rate, and individuals carrying…

Probability · Mathematics 2026-01-01 Jan Lukas Igelbrink , Charline Smadi , Anton Wakolbinger

We consider the Moran process with two populations competing under an iterated Prisoners' Dilemma in the presence of mutation, and concentrate on the case where there are multiple Evolutionarily Stable Strategies. We perform a complete…

Dynamical Systems · Mathematics 2015-12-23 Lee DeVille , Meghan Galiardi

Numerous experimental studies have demonstrated that the microenvironment is a key regulator influencing the proliferative and migrative potentials of species. Spatial and temporal disturbances lead to adverse and hazardous…

Populations and Evolution · Quantitative Biology 2015-10-07 Venkata. S. K. Manem , Kamran Kaveh , Mohammad Kohandel , Siv Sivaloganathan

We study the competition between several advantageous mutants in an asexual population (clonal interference) as a function of the time between the appearance of the mutants, their selective advantages, and the rate of deleterious mutations.…

Biological Physics · Physics 2007-05-23 Paulo R. A. Campos , Christoph Adami , Claus O. Wilke