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Fluidic iontronics offer a unique capability for emulating the chemical processes found in neurons. We extract multiple distinct chemically regulated synaptic features from an experimentally accessible conical microfluidic channel carrying…

Soft Condensed Matter · Physics 2026-02-13 T. M. Kamsma , M. S. Klop , W. Q. Boon , C. Spitoni , B. Rueckauer , R. van Roij

We present an integrated iontronic memristor circuit that reproduces biologically inspired Spike Rate-Dependent Plasticity (SRDP) and functions as a physical nonlinear frequency kernel, which we demonstrate can be used to classify natural…

Soft Condensed Matter · Physics 2026-03-23 T. M. Kamsma , Y. Gu , D. Shi , C. Spitoni , M. Dijkstra , R. van Roij , Y. Xie

A model of a finite cylindrical ion channel through a phospholipid membrane of width $L$ separating two electrolyte reservoirs is studied. Analytical solution of the Poisson equation is obtained for an arbitrary distribution of ions inside…

Soft Condensed Matter · Physics 2009-11-11 Yan Levin

We consider the Poisson-Nernst-Planck system which is well-accepted for describing dilute electrolytes as well as transport of charged species in homogeneous environments. Here, we study these equations in porous media whose electric…

Mathematical Physics · Physics 2013-02-26 Markus Schmuck

To obtain precisely controllable, robust as well as reproduceable memristor for efficient neuromorphic computing still very challenging. Molecular tailoring aims at obtaining the much more flexibly tuning plasticity has recently generated…

Mesoscale and Nanoscale Physics · Physics 2017-04-06 Zhiyong Wang , Laiyuan Wang , Masaru Nagai , Linghai Xie , Haifeng Ling , Qi Li , Ying Zhu , Tengfei Li , Mingdong Yi , Naien Shi , Wei Huang

Using molecular dynamics simulations, we show that, when subject to a periodic external electric field, a nanopore in ionic solution acts as a capacitor with memory (memcapacitor) at various frequencies and strengths of the electric field.…

Soft Condensed Matter · Physics 2010-07-20 Matt Krems , Yuriy V. Pershin , Massimiliano Di Ventra

The molecular mechanism of ion channel gating and substrate modulation is elusive for many voltage gated ion channels, such as eukaryotic sodium ones. The understanding of channel functions is a pressing issue in molecular biophysics and…

Biomolecules · Quantitative Biology 2016-11-15 Duan Chen , Guowei Wei

Ultrafast, time-resolved spectroscopies enable the direct observation of non-equilibrium processes in condensed-phase systems and have revealed key insights into energy transport, hydrogen-bond dynamics, and vibrational coupling. While ab…

Chemical Physics · Physics 2025-09-01 Kit Joll , Philipp Schienbein

Recent advances in nanofluidics have enabled the confinement of water down to a single molecular layer. Such monolayer electrolytes show promise in achieving bio-inspired functionalities through molecular control of ion transport. However,…

Soft Condensed Matter · Physics 2021-09-08 Paul Robin , Nikita Kavokine , Lydéric Bocquet

Inspired by the brain, we present a physical alternative to traditional digital neural networks -- a microfluidic network in which nodes are connected by conical, electrolyte-filled channels acting as memristive iontronic synapses. Their…

Soft Condensed Matter · Physics 2025-11-07 Monica Conte , René van Roij , Marjolein Dijkstra

Microfluidic channels with embedded ion permselective medium under the application of electric current are commonly used for electrokinetic processes as on-chip ion concentration polarization (ICP) and bioparticle preconcentration to…

Fluid Dynamics · Physics 2022-11-22 Barak Sabbagh , Sinwook Park , Gilad Yossifon

Memristive circuit elements constitute a cornerstone for novel electronic applications, such as neuromorphic computing, called to revolutionize information technologies. By definition, memristors are sensitive to the history of electrical…

We develop a simple model of ionic current through neuronal membranes as a function of membrane potential and extracellular ion concentration. The model combines a simplified Poisson-Nernst-Planck (PNP) model of ion transport through…

Biological Physics · Physics 2023-09-06 Linda Werneck , Mertcan Han , Erdost Yildiz , Marc-André Keip , Metin Sitti , Michael Ortiz

Microtubules (MTs) are important cytoskeletal structures, engaged in a number of specific cellular activities, including vesicular traffic, cell cyto-architecture and motility, cell division, and information processing within neuronal…

Subcellular Processes · Quantitative Biology 2007-05-23 Avner Priel , Arnolt J. Ramos , Jack A. Tuszynski , Horacio F. Cantiello

The movement of ionic solutions is an essential part of biology and technology. Fluidics, from nano- to micro- to microfluidics, is a burgeoning area of technology which is all about the movement of ionic solutions, on various scales. Many…

Quantitative Methods · Quantitative Biology 2018-06-08 Shixin Xu , Bob Eisenberg , Zilong Song , Huaxiong Huang

Atomic ions confined in multi-electrode traps have been proposed as a basis for scalable quantum information processing. This scheme involves transporting ions between spatially distinct locations by use of time-varying electric potentials…

Atomic Physics · Physics 2015-06-12 R. Bowler , U. Warring , J. W. Britton , B. C. Sawyer , J. Amini

Molecular Dynamics simulations of water molecules in nanometre sized cylindrical channels connecting two reservoirs show that the permeation of water is very sensitive to the channel radius and to electric polarization of the embedding…

Soft Condensed Matter · Physics 2009-11-07 Rosalind Allen , Simone Melchionna , Jean-Pierre Hansen

Although materials and processes are different from biological cells', brain mimicries led to tremendous achievements in massively parallel information processing via neuromorphic engineering. Inexistent in electronics, we describe how to…

Disordered Systems and Neural Networks · Physics 2022-01-05 Kamila Janzakova , Ankush Kumar , Mahdi Ghazal , Anna Susloparova , Yannick Coffinier , Fabien Alibart , Sebastien Pecqueur

Brain-inspired computing has the potential to revolutionise the current von Neumann architecture, advancing machine learning applications. Signal transmission in the brain relies on voltage-gated ion channels, which exhibit the electrical…

Using both analytic and numerical analyses of the Poisson-Nernst-Planck equations we theoretically investigate the electric conductivity of a conical channel, which in accordance with recent experiments exhibits a strong non-linear pressure…

Soft Condensed Matter · Physics 2022-10-19 Willem Boon , Tim Veenstra , Marjolein Dijkstra , René van Roij