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Light sheet fluorescence microscopy (LSM) enables high-resolution, three-dimensional (3D) imaging of biological specimens, providing rich volumetric data for studying cellular organization, pathology, and vascular networks. However, the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Adina Scheinfeld , Haotan Zhang , Shang Mu , Rudolf L. M. van Herten , Lucas Stoffl , Ali Erturk , Zhuhao Wu , Johannes C. Paetzold

Deformable image registration across heterogeneous domains remains challenging because coupled appearance variation and geometric misalignment violate the brightness constancy assumption underlying conventional methods. We propose…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Jiahao Qin

Computed Tomography (CT)/X-ray registration in image-guided navigation remains challenging because of its stringent requirements for high accuracy and real-time performance. Traditional "render and compare" methods, relying on iterative…

Computer Vision and Pattern Recognition · Computer Science 2025-09-01 Ao Shen , Xueming Fu , Junfeng Jiang , Qiang Zeng , Ye Tang , Zhengming Chen , Luming Nong , Feng Wang , S. Kevin Zhou

Ultrahigh field (UHF) Magnetic Resonance Imaging (MRI) offers an elevated signal-to-noise ratio (SNR), enabling exceptionally high spatial resolution that benefits both clinical diagnostics and advanced research. However, the jump to higher…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Zhengyi Lu , Hao Liang , Ming Lu , Xiao Wang , Xinqiang Yan , Yuankai Huo

Deformable medical image registration is a fundamental task in medical image analysis with applications in disease diagnosis, treatment planning, and image-guided interventions. Despite significant advances in deep learning based…

Machine Learning · Computer Science 2026-02-10 Muhammad Zafar Iqbal , Ghazanfar Farooq Siddiqui , Anwar Ul Haq , Imran Razzak

Method: ProRSeg was trained using 5-fold cross-validation with 110 T2-weighted MRI acquired at 5 treatment fractions from 10 different patients, taking care that same patient scans were not placed in training and testing folds. Segmentation…

Image and Video Processing · Electrical Eng. & Systems 2022-11-17 Jue Jiang , Jun Hong , Kathryn Tringale , Marsha Reyngold , Christopher Crane , Neelam Tyagi , Harini Veeraraghavan

Organ at risk (OAR) segmentation is a critical process in radiotherapy treatment planning such as head and neck tumors. Nevertheless, in clinical practice, radiation oncologists predominantly perform OAR segmentations manually on CT scans.…

Computer Vision and Pattern Recognition · Computer Science 2024-03-04 Zeyu Zhang , Xuyin Qi , Bowen Zhang , Biao Wu , Hien Le , Bora Jeong , Zhibin Liao , Yunxiang Liu , Johan Verjans , Minh-Son To , Richard Hartley

Registration plays an important role in medical image analysis. Deep learning-based methods have been studied for medical image registration, which leverage convolutional neural networks (CNNs) for efficiently regressing a dense deformation…

Computer Vision and Pattern Recognition · Computer Science 2022-08-16 Xiaoru Gao , GuoYan Zheng

Light sheet fluorescence microscopy (LSFM) has transformed the way we visualize biological tissues in three dimensions, offering high-resolution imaging while minimizing photo-induced damage to the samples. Recent breakthroughs in…

Optics · Physics 2025-05-27 Alireza Tabatabaei Mashayekh , Jeremy Witzens

Magnetic Resonance Fingerprinting (MRF) is an emerging technology with the potential to revolutionize radiology and medical diagnostics. In comparison to traditional magnetic resonance imaging (MRI), MRF enables the rapid, simultaneous,…

Deformable image registration plays a critical role in various tasks of medical image analysis. A successful registration algorithm, either derived from conventional energy optimization or deep networks requires tremendous efforts from…

Computer Vision and Pattern Recognition · Computer Science 2023-08-15 Xin Fan , Zi Li , Ziyang Li , Xiaolin Wang , Risheng Liu , Zhongxuan Luo , Hao Huang

Medical image segmentation is vital for clinical diagnosis, yet current deep learning methods often demand extensive expert effort, i.e., either through annotating large training datasets or providing prompts at inference time for each new…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Xingjian Li , Qifeng Wu , Adithya S. Ubaradka , Yiran Ding , Colleen Que , Runmin Jiang , Jianhua Xing , Tianyang Wang , Min Xu

Diffeomorphic image registration is crucial for various medical imaging applications because it can preserve the topology of the transformation. This study introduces DCCNN-LSTM-Reg, a learning framework that evolves dynamically and learns…

Image and Video Processing · Electrical Eng. & Systems 2024-11-06 Jinqiu Deng , Ke Chen , Mingke Li , Daoping Zhang , Chong Chen , Alejandro F. Frangi , Jianping Zhang

Computed tomography (CT) report generation is crucial to assist radiologists in interpreting CT volumes, which can be time-consuming and labor-intensive. Existing methods primarily only consider the global features of the entire volume,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-06 Zhixuan Chen , Yequan Bie , Haibo Jin , Hao Chen

We propose MeshLRM, a novel LRM-based approach that can reconstruct a high-quality mesh from merely four input images in less than one second. Different from previous large reconstruction models (LRMs) that focus on NeRF-based…

Computer Vision and Pattern Recognition · Computer Science 2025-01-24 Xinyue Wei , Kai Zhang , Sai Bi , Hao Tan , Fujun Luan , Valentin Deschaintre , Kalyan Sunkavalli , Hao Su , Zexiang Xu

Histological analysis plays a crucial role in understanding tissue structure and pathology. While recent advancements in registration methods have improved 2D histological analysis, they often struggle to preserve critical 3D spatial…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Juming Xiong , Ruining Deng , Jialin Yue , Siqi Lu , Junlin Guo , Marilyn Lionts , Tianyuan Yao , Can Cui , Junchao Zhu , Chongyu Qu , Mengmeng Yin , Haichun Yang , Yuankai Huo

Pretraining large language models (LLMs) with next-token prediction has led to remarkable advances, yet the context-dependent nature of token embeddings in such models results in high intra-class variance and inter-class similarity, thus…

Computation and Language · Computer Science 2026-05-12 Yan Sun , Guoxia Wang , Jinle Zeng , JiaBin Yang , Shuai Li , Li Shen , Dacheng Tao , DianHai Yu , Haifeng Wang

The measurement of retinal blood flow (RBF) in capillaries can provide a powerful biomarker for the early diagnosis and treatment of ocular diseases. However, no single modality can determine capillary flowrates with high precision.…

Image and Video Processing · Electrical Eng. & Systems 2024-07-16 Chiao-Yi Wang , Faranguisse Kakhi Sadrieh , Yi-Ting Shen , Shih-En Chen , Sarah Kim , Victoria Chen , Achyut Raghavendra , Dongyi Wang , Osamah Saeedi , Yang Tao

Deformable registration is crucial in medical imaging. Several existing applications include lesion tracking, probabilistic atlas generation, and treatment response evaluation. However, current methods often lack robustness and…

Image and Video Processing · Electrical Eng. & Systems 2026-03-04 Yunzheng Zhu , Aichi Chien , Kimaya kulkarni , Luoting Zhuang , Stephen Park , Ricky Savjani , Daniel Low , William Hsu

Volumetric biomedical microscopy has the potential to increase the diagnostic information extracted from clinical tissue specimens and improve the diagnostic accuracy of both human pathologists and computational pathology models.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-16 Cheng Jiang , Alexander Gedeon , Yiwei Lyu , Eric Landgraf , Yufeng Zhang , Xinhai Hou , Akhil Kondepudi , Asadur Chowdury , Honglak Lee , Todd Hollon