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Resorbable magnesium (Mg) alloys are promising candidates for temporary medical devices due to their biodegradability and favorable mechanical properties. To accelerate the design of diluted Mg alloys for implants, we developed a…

Materials Science · Physics 2026-04-23 Vickey Nandal , Vít Beneš , Pavel Baláž , Jiří Ryjáček , Karel Tesař

Zinc alloys are recognised for their excellent biocompatibility and favourable corrosion rates, making them suitable for bioabsorbable implants. However, their mechanical properties necessitate improvement to fulfil the rigorous…

Zinc alloys have emerged as promising candidates for biodegradable materials due to their remarkable biocompatibility and favorable mechanical characteristics. The incorporation of alloying elements plays an essential role in advancing the…

Magnesium alloys are attractive options for temporary bio-implants because of their biocompatibility, controlled corrosion rate, and similarity to natural bone in terms of stiffness and density. Nevertheless, their low mechanical strength…

Materials Science · Physics 2023-05-23 Parham Valipoorsalimi , Yuksel Asli Sari , Mihriban Pekguleryuz

Magnesium and its alloys are ideal for biodegradable implants due to their biocompatibility and their low-stress shielding. However, they can corrode too rapidly in the biological environment. The objective of this research was to develop…

Materials Science · Physics 2017-06-28 Sohrab Khalifeh , T. David Burleigh

Magnesium and its alloys are intriguing as possible biodegradable biomaterials due to their unique combination of biodegradability and high specific mechanical properties. However, uncontrolled biodegradation of magnesium during…

Materials Science · Physics 2016-11-16 Reece N. Oosterbeek , Christopher K. Seal , Mark P. Staiger , Margaret M. Hyland

Machine Learning (ML) has impacted numerous areas of materials science, most prominently improving molecular simulations, where force fields were trained on previously relaxed structures. One natural next step is to predict material…

Materials Science · Physics 2023-11-28 Robin Hilgers , Daniel Wortmann , Stefan Blügel

Magnesium (Mg) has the lowest density of all structural metals and has excellent potential for wide use in structural applications. While pure Mg has inferior mechanical properties; the addition of further elements at various concentrations…

Bioresorbable Mg-based alloys with low density, low elastic modulus, and excellent biocompatibility are outstanding candidates for temporary orthopedic implants. Coincidentally, metal additive manufacturing (AM) is disrupting the biomedical…

Materials Science · Physics 2024-04-25 D. Tourret , R. Tavakoli , A. D. Boccardo , A. K. Boukellal , M. Li , J. Molina-Aldareguia

High-temperature alloy design requires a concurrent consideration of multiple mechanisms at different length scales. We propose a workflow that couples highly relevant physics into machine learning (ML) to predict properties of complex…

Materials Science · Physics 2020-09-04 Jian Peng , Yukinori Yamamoto , Jeffrey A. Hawk , Edgar Lara-Curzio , Dongwon Shin

Magnesium (Mg) alloys have shown great prospects as both structural and biomedical materials, while poor corrosion resistance limits their further application. In this work, to avoid the time-consuming and laborious experiment trial, a…

Materials Science · Physics 2022-01-25 Yaowei Wang , Tian Xie , Qingli Tang , Mingxu Wang , Tao Ying , Hong Zhu , Xiaoqin Zeng

Despite the advantages of using biodegradable metals in implant design, their uncontrolled degradation and release remain a challenge in practical applications. A validated computational model of the degradation process can facilitate the…

Computational Engineering, Finance, and Science · Computer Science 2021-07-28 Mojtaba Barzegari , Di Mei , Sviatlana V. Lamaka , Liesbet Geris

Grain boundary (GB) segregation in magnesium (Mg) substantially influences its mechanical properties and performance. Atomic-scale modelling, typically using ab-initio or semi-empirical approaches, has mainly focused on GB segregation at…

Dilute Mg-Zn wires are of great interest for biodegradable small-bone fixation, as magnesium degradation can support bone-related processes, while low zinc additions may provide biological benefits without compromising biocompatibility. In…

Materials Science · Physics 2026-05-04 Jiří Ryjáček , Leonard Hlodák , Jiří Liška , Jan Pinc , Tomáš Herma , Karel Tesař

Once the magnesium alloy was implanted in the body, it was immediately covered with plasma proteins. The coated alloy surface promoted the adsorption and growth of osteoblasts. Herein, in vitro biological reactions of the ZK60 and AZ31…

Biological Physics · Physics 2022-07-26 Xian Wei , Jiajia Menga , Sujie Ma , Yanchun Li , Hong Qing , Xubiao Peng , Bo Zhang , Qing Zhao

Machine learning (ML) is shown to predict new alloys and their performances in a high dimensional, multiple-target-property design space that considers chemistry, multi-step processing routes, and characterization methodology variations. A…

Materials Science · Physics 2020-10-12 Sen Liu , Branden B. Kappes , Behnam Amin-ahmadi , Othmane Benafan , Xiaoli Zhang , Aaron P. Stebner

We study a cast Mg-4.65Al-2.82Ca alloy with a microstructure containing $\alpha$-Mg matrix reinforced with a C36 Laves phase skeleton. Such ternary alloys are targeted for elevated temperature applications in automotive engines since they…

The wear resistance of magnesium and its alloys is very poor due to their inherent low hardness and poor tribological properties. Improving the wear resistance of magnesium and its alloys plays a significant role in expanding their…

Materials Science · Physics 2025-01-03 Tianxiang Peng , Liang Wang

In silico testing of implant materials is a research area of high interest, as cost- and labour-intensive experiments may be omitted. However, assessing the tissue-material interaction mathematically and computationally can be very complex,…

Microstructural features and mechanical properties of an Al-Mg-Si alloy processed by high-pressure torsion have been investigated using transmission electron microscopy, X-ray diffraction, three-dimensional atom probe, tensile tests and…

Materials Science · Physics 2008-08-28 Gulnaz Nurislamova , Xavier Sauvage , Maxim Murashkin , Rinat Islamgaliev , Ruslan Valiev
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