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Spatial transcriptomics (ST) technologies have revolutionized the study of gene expression patterns in tissues by providing multimodality data in transcriptomic, spatial, and morphological, offering opportunities for understanding tissue…

Computational Engineering, Finance, and Science · Computer Science 2024-01-17 Zelin Zang , Liangyu Li , Yongjie Xu , Chenrui Duan , Kai Wang , Yang You , Yi Sun , Stan Z. Li

Hyperspectral images (HSI) have become popular for analysing remotely sensed images in multiple domain like agriculture, medical. However, existing models struggle with complex relationships and characteristics of spectral-spatial data due…

Computer Vision and Pattern Recognition · Computer Science 2023-12-21 Neetu Sigger , Tuan Thanh Nguyen , Gianluca Tozzi , Quoc-Tuan Vien , Sinh Van Nguyen

Histo-genomic multi-modal methods have recently emerged as a powerful paradigm, demonstrating significant potential for improving cancer prognosis. However, genome sequencing, unlike histopathology imaging, is still not widely accessible in…

Image and Video Processing · Electrical Eng. & Systems 2024-03-19 Zhikang Wang , Yumeng Zhang , Yingxue Xu , Seiya Imoto , Hao Chen , Jiangning Song

Histopathological image segmentation is a laborious and time-intensive task, often requiring analysis from experienced pathologists for accurate examinations. To reduce this burden, supervised machine-learning approaches have been adopted…

Computer Vision and Pattern Recognition · Computer Science 2024-09-12 Vishnuvardhan Purma , Suhas Srinath , Seshan Srirangarajan , Aanchal Kakkar , Prathosh A. P

Digital pathology has advanced significantly over the last decade, with Whole Slide Images (WSIs) encompassing vast amounts of data essential for accurate disease diagnosis. High-resolution WSIs are essential for precise diagnosis but…

Image and Video Processing · Electrical Eng. & Systems 2024-08-28 Xuan Xu , Saarthak Kapse , Prateek Prasanna

Scene Text Image Super-Resolution (STISR) aims to enhance the resolution and legibility of text within low-resolution (LR) images, consequently elevating recognition accuracy in Scene Text Recognition (STR). Previous methods predominantly…

Computer Vision and Pattern Recognition · Computer Science 2023-11-23 Yuxuan Zhou , Liangcai Gao , Zhi Tang , Baole Wei

Spatial transcriptomics (ST) provides spatially resolved measurements of gene expression, enabling characterization of the molecular landscape of human tissue beyond histological assessment as well as localized readouts that can be aligned…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Konstantin Hemker , Andrew H. Song , Cristina Almagro-Pérez , Guillaume Jaume , Sophia J. Wagner , Anurag Vaidya , Nikola Simidjievski , Mateja Jamnik , Faisal Mahmood

Advances in spatial transcriptomics (ST) technologies enable systematic molecular characterization of tumor microenvironment, tumor gradients and gene regulatory networks. Cancer progression is known to vary along pathological gradients,…

Automatic segmentation of the prostate cancer from the multi-modal magnetic resonance images is of critical importance for the initial staging and prognosis of patients. However, how to use the multi-modal image features more efficiently is…

Image and Video Processing · Electrical Eng. & Systems 2020-11-10 Guokai Zhang , Xiaoang Shen , Ye Luo , Jihao Luo , Zeju Wang , Weigang Wang , Binghui Zhao , Jianwei Lu

Scene Text Image Super-resolution (STISR) has recently achieved great success as a preprocessing method for scene text recognition. STISR aims to transform blurred and noisy low-resolution (LR) text images in real-world settings into clear…

Computer Vision and Pattern Recognition · Computer Science 2023-12-25 Chihiro Noguchi , Shun Fukuda , Masao Yamanaka

Restoring low-resolution text images presents a significant challenge, as it requires maintaining both the fidelity and stylistic realism of the text in restored images. Existing text image restoration methods often fall short in hard…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Chenglu Pan , Xiaogang Xu , Ganggui Ding , Yunke Zhang , Wenbo Li , Jiarong Xu , Qingbiao Wu

Spatial Transcriptomics (ST) profiles thousands of gene expression values at discrete spots with precise coordinates on tissue sections, preserving spatial context essential for clinical and pathological studies. With rising sequencing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Yishun Zhu , Jiaxin Qi , Jian Wang , Yuhua Zheng , Jianqiang Huang

Hyperspectral image (HSI) denoising is a crucial preprocessing procedure for the subsequent HSI applications. Unfortunately, though witnessing the development of deep learning in HSI denoising area, existing convolution-based methods face…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Miaoyu Li , Ying Fu , Yulun Zhang

While recent advancements in Image Super-Resolution (SR) using diffusion models have shown promise in improving overall image quality, their application to scene text images has revealed limitations. These models often struggle with…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Keren Ye , Ignacio Garcia Dorado , Michalis Raptis , Mauricio Delbracio , Irene Zhu , Peyman Milanfar , Hossein Talebi

Multiplex imaging is revolutionizing pathology by enabling the simultaneous visualization of multiple biomarkers within tissue samples, providing molecular-level insights that traditional hematoxylin and eosin (H&E) staining cannot provide.…

Image and Video Processing · Electrical Eng. & Systems 2026-01-06 Hyun-Jic Oh , Junsik Kim , Zhiyi Shi , Yichen Wu , Yu-An Chen , Peter K Sorger , Hanspeter Pfister , Won-Ki Jeong

Identifying disease-indicative genes is critical for deciphering disease mechanisms and has attracted significant interest in biomedical research. Spatial transcriptomics offers unprecedented insights for the detection of disease-specific…

Methodology · Statistics 2024-09-05 Qicheng Zhao , Qihuang Zhang

Hyperspectral image denoising faces the challenge of multi-dimensional coupling of spatially non-uniform noise and spectral correlation interference. Existing deep learning methods mostly focus on RGB images and struggle to effectively…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Haoyue Li , Di Wu

Spatial transcriptomics has revolutionized tissue analysis by simultaneously mapping gene expression, spatial topography, and histological context across consecutive tissue sections, enabling systematic investigation of spatial…

Applications · Statistics 2025-10-24 Meng Zhou , Shuangge Ma , Mengyun Wu

Self-supervised learning has demonstrated considerable potential in hyperspectral representation, yet its application in cross-domain transfer scenarios remains under-explored. Existing methods, however, still rely on source domain…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Jianshu Chao , Tianhua Lv , Qiqiong Ma , Yunfei Qiu , Li Fang , Huifang Shen , Wei Yao

Accurate detection of cancer tissue regions (CTR) enables deeper analysis of the tumor microenvironment and offers crucial insights into treatment response. Traditional CTR detection methods, which typically rely on the rich cellular…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Shuailin Xue , Jun Wan , Lihua Zhang , Wenwen Min