English
Related papers

Related papers: Cross-modal Diffusion Modelling for Super-resolved…

200 papers

Spatial transcriptomics (ST) measures gene expression at fine-grained spatial resolution, offering insights into tissue molecular landscapes. Previous methods for spatial gene expression prediction typically crop spots of interest from…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Ruikun Zhang , Yan Yang , Liyuan Pan

In clinical practice, tri-modal medical image fusion, compared to the existing dual-modal technique, can provide a more comprehensive view of the lesions, aiding physicians in evaluating the disease's shape, location, and biological…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Yushen Xu , Xiaosong Li , Yuchan Jie , Haishu Tan

Diffusion models have recently achieved significant success in various image manipulation tasks, including image super-resolution and perceptual quality enhancement. Pretrained text-to-image models, such as Stable Diffusion, have exhibited…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Sanchar Palit , Subhasis Chaudhuri , Biplab Banerjee

Spatial transcriptomics (ST) is a novel technique that simultaneously captures pathological images and gene expression profiling with spatial coordinates. Since ST is closely related to pathological features such as disease subtypes, it may…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Kazuya Nishimura , Ryoma Bise , Yasuhiro Kojima

Spatial transcriptomics enables simultaneous measurement of gene expression and tissue morphology, offering unprecedented insights into cellular organization and disease mechanisms. However, the field lacks comprehensive benchmarks for…

Denoising diffusion models have emerged as the go-to generative framework for solving inverse problems in imaging. A critical concern regarding these models is their performance on out-of-distribution tasks, which remains an under-explored…

Computer Vision and Pattern Recognition · Computer Science 2025-01-29 Riccardo Barbano , Alexander Denker , Hyungjin Chung , Tae Hoon Roh , Simon Arridge , Peter Maass , Bangti Jin , Jong Chul Ye

Spatial transcriptomics is a modern sequencing technology that allows the measurement of the activity of thousands of genes in a tissue sample and map where the activity is occurring. This technology has enabled the study of the so-called…

Methodology · Statistics 2022-09-15 Andrea Sottosanti , Davide Risso

3D Swin Transformer (3D-ST) known for its hierarchical attention and window-based processing, excels in capturing intricate spatial relationships within images. Spatial-spectral Transformer (SST), meanwhile, specializes in modeling…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Muhammad Ahmad , Manuel Mazzara , Salvatore Distifano

High-resolution computed tomography (CT) imaging is essential for medical diagnosis but requires increased radiation exposure, creating a critical trade-off between image quality and patient safety. While deep learning methods have shown…

Image and Video Processing · Electrical Eng. & Systems 2025-06-16 Chunlei Li , Yilei Shi , Haoxi Hu , Jingliang Hu , Xiao Xiang Zhu , Lichao Mou

Recent advances in computational pathology have leveraged vision-language models to learn joint representations of Hematoxylin and Eosin (HE) images with spatial transcriptomic (ST) profiles. However, existing approaches typically align HE…

In multi-class histopathology nuclei analysis tasks, the lack of training data becomes a main bottleneck for the performance of learning-based methods. To tackle this challenge, previous methods have utilized generative models to increase…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Seonghui Min , Hyun-Jic Oh , Won-Ki Jeong

Tumour heterogeneity in breast cancer poses challenges in predicting outcome and response to therapy. Spatial transcriptomics technologies may address these challenges, as they provide a wealth of information about gene expression at the…

Image and Video Processing · Electrical Eng. & Systems 2023-09-19 Md Mamunur Rahaman , Ewan K. A. Millar , Erik Meijering

Spatial transcriptomics provides a molecularly rich description of tissue organization, enabling unsupervised discovery of tissue niches -- spatially coherent regions of distinct cell-type composition and function that are relevant to both…

Computer Vision and Pattern Recognition · Computer Science 2026-04-13 Arbel Hizmi , Artemii Bakulin , Shai Bagon , Nir Yosef

Spatial Transcriptomics (ST) is a method that captures gene expression profiles aligned with spatial coordinates. The discrete spatial distribution and the super-high dimensional sequencing results make ST data challenging to be modeled…

Machine Learning · Computer Science 2025-05-08 Qingtian Zhu , Yumin Zheng , Yuling Sang , Yifan Zhan , Ziyan Zhu , Jun Ding , Yinqiang Zheng

Spatial transcriptomics (ST) measures gene expression at a set of spatial locations in a tissue. Communities of nearby cells that express similar genes form \textit{spatial domains}. Specialized ST clustering algorithms have been developed…

Quantitative Methods · Quantitative Biology 2025-11-12 Perry Beamer , Zixuan Cang

Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima

Spatial transcriptomics (ST) has emerged as an advanced technology that provides spatial context to gene expression. Recently, deep learning-based methods have shown the capability to predict gene expression from WSI data using ST data.…

Machine Learning · Computer Science 2024-12-10 Mingcheng Qu , Yuncong Wu , Donglin Di , Anyang Su , Tonghua Su , Yang Song , Lei Fan

Improving the spatial resolution of CT images is a meaningful yet challenging task, often accompanied by the issue of noise amplification. This article introduces an innovative framework for noise-controlled CT super-resolution utilizing…

Computer Vision and Pattern Recognition · Computer Science 2025-02-17 Yuang Wang , Siyeop Yoon , Rui Hu , Baihui Yu , Duhgoon Lee , Rajiv Gupta , Li Zhang , Zhiqiang Chen , Dufan Wu

The effectiveness of spectral-spatial feature learning is crucial for the hyperspectral image (HSI) classification task. Diffusion models, as a new class of groundbreaking generative models, have the ability to learn both contextual…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Jingyi Zhou , Jiamu Sheng , Jiayuan Fan , Peng Ye , Tong He , Bin Wang , Tao Chen

Recent advancements in Spatial Transcriptomics (ST) technology have facilitated detailed gene expression analysis within tissue contexts. However, the high costs and methodological limitations of ST necessitate a more robust predictive…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Youngmin Chung , Ji Hun Ha , Kyeong Chan Im , Joo Sang Lee