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Multiplexed imaging allows multiple cell types to be simultaneously visualised in a single tissue sample, generating unprecedented amounts of spatially-resolved, biological data. In topological data analysis, persistent homology provides…

Quantitative Methods · Quantitative Biology 2025-05-06 Maria Torras-Pérez , Iris H. R. Yoon , Praveen Weeratunga , Ling-Pei Ho , Helen M. Byrne , Ulrike Tillmann , Heather A. Harrington

We give bounds for dimension 0 persistent homology and codimension 1 homology of Vietoris--Rips, alpha, and cubical complex filtrations from finite sets related by enrichment (adding new elements), sparsification (removing elements), and…

Algebraic Topology · Mathematics 2025-12-05 Jānis Lazovskis , Ran Levi , Juliano Morimoto

Topology applied to real world data using persistent homology has started to find applications within machine learning, including deep learning. We present a differentiable topology layer that computes persistent homology based on level set…

Representation learning on graphs is a fundamental problem that can be crucial in various tasks. Graph neural networks, the dominant approach for graph representation learning, are limited in their representation power. Therefore, it can be…

Machine Learning · Computer Science 2025-01-17 Zuoyu Yan , Qi Zhao , Ze Ye , Tengfei Ma , Liangcai Gao , Zhi Tang , Yusu Wang , Chao Chen

Visualization in the emerging field of topological data analysis has progressed from persistence barcodes and persistence diagrams to display of two-parameter persistent homology. Although persistence barcodes and diagrams have permitted…

Applications · Statistics 2019-01-08 Raoul R. Wadhwa , Andrew Dhawan , Drew F. K. Williamson , Jacob G. Scott

This paper is a survey of persistent homology, primarily as it is used in topological data analysis. It includes the theory of persistence modules, as well as stability theorems for persistence barcodes, generalized persistence,…

Algebraic Topology · Mathematics 2020-04-03 Gunnar Carlsson

Understanding the decision-making processes of large language models is critical given their widespread applications. To achieve this, we aim to connect a formal mathematical framework - zigzag persistence from topological data analysis -…

Computation and Language · Computer Science 2025-06-16 Yuri Gardinazzi , Karthik Viswanathan , Giada Panerai , Alessio Ansuini , Alberto Cazzaniga , Matteo Biagetti

Topological data analysis (TDA) has had enormous success in science and engineering in the past decade. Persistent topological Laplacians (PTLs) overcome some limitations of persistent homology, a key technique in TDA, and provide…

Algebraic Topology · Mathematics 2023-12-05 Benjamin Jones , Guowei Wei

Given a finite set in a metric space, the topological analysis generalizes hierarchical clustering using a 1-parameter family of homology groups to quantify connectivity in all dimensions. The connectivity is compactly described by the…

Computational Geometry · Computer Science 2016-07-22 Herbert Edelsbrunner , Hubert Wagner

Appropriately representing elements in a database so that queries may be accurately matched is a central task in information retrieval; recently, this has been achieved by embedding the graphical structure of the database into a manifold in…

Machine Learning · Statistics 2023-07-10 Yueqi Cao , Athanasios Vlontzos , Luca Schmidtke , Bernhard Kainz , Anthea Monod

A fundamental tool in topological data analysis is persistent homology, which allows extraction of information from complex datasets in a robust way. Persistent homology assigns a module over a principal ideal domain to a one-parameter…

Algebraic Topology · Mathematics 2019-06-19 Heather A. Harrington , Nina Otter , Hal Schenck , Ulrike Tillmann

We study the persistent homology of both functional data on compact topological spaces and structural data presented as compact metric measure spaces. One of our goals is to define persistent homology so as to capture primarily properties…

Algebraic Topology · Mathematics 2018-11-27 Haibin Hang , Facundo Mémoli , Washington Mio

We present a topology-informed approach for classifying particle jets using persistent homology, a framework that captures the structural properties of point clouds. Particle jets produced in proton-proton collisions consist of cascades of…

High Energy Physics - Phenomenology · Physics 2026-01-06 Saurav Mittal

Recent years have witnessed a fast growth in mathematical artificial intelligence (AI). One of the most successful mathematical AI approaches is topological data analysis (TDA) via persistent homology (PH) that provides explainable AI (xAI)…

General Topology · Mathematics 2025-10-27 Yiming Ren , Guowei Wei

In the study of dynamical systems on networks/graphs, a key theme is how the network topology influences stability for steady states or synchronized states. Ideally, one would like to derive conditions for stability or instability that…

Dynamical Systems · Mathematics 2020-07-01 Raffaella Mulas , Christian Kuehn , Jürgen Jost

Algorithms for persistent homology and zigzag persistent homology are well-studied for persistence modules where homomorphisms are induced by inclusion maps. In this paper, we propose a practical algorithm for computing persistence under…

Computational Geometry · Computer Science 2014-03-26 Tamal K. Dey , Fengtao Fan , Yusu Wang

This paper is a cursory study on how topological features are preserved within the internal representations of neural network layers. Using techniques from topological data analysis, namely persistent homology, the topological features of a…

Machine Learning · Computer Science 2022-08-16 Archie Shahidullah

A central problem in data-driven scientific inquiry is how to interpret structure in noisy, high-dimensional data. Topological data analysis (TDA) provides a solution via persistent homology, which encodes features of interest as…

Algebraic Topology · Mathematics 2026-02-04 Christian Lentz , Gregory Henselman-Petrusek , Lori Ziegelmeier

Despite the vast literature on network dynamics, we still lack basic insights into dynamics on higher-order structures (e.g., edges, triangles, and more generally, $k$-dimensional "simplices") and how they are influenced through…

Physics and Society · Physics 2022-03-14 Cameron Ziegler , Per Sebastian Skardal , Haimonti Dutta , Dane Taylor

This work explores the use of topological tools for achieving effective non-prehensile manipulation in cluttered, constrained workspaces. In particular, it proposes the use of persistent homology as a guiding principle in identifying the…

Robotics · Computer Science 2022-02-08 Ewerton R. Vieira , Daniel Nakhimovich , Kai Gao , Rui Wang , Jingjin Yu , Kostas E. Bekris
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