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One of the paramount challenges in neuroscience is to understand the dynamics of individual neurons and how they give rise to network dynamics when interconnected. Historically, researchers have resorted to graph theory, statistics, and…

Neurons and Cognition · Quantitative Biology 2019-02-08 Jean-Baptiste Bardin , Gard Spreemann , Kathryn Hess

We use topological data analysis to study neural population activity in the Sensorium 2023 dataset, which records responses from thousands of mouse visual cortex neurons to diverse video stimuli. For each video, we build frame-by-frame…

Algebraic Topology · Mathematics 2026-03-04 Yuri Gardinazzi , Alessio Ansuini , Eugenio Piasini , Fabio Anselmi , Matteo Biagetti

Persistent homology (PH) is a recently developed theory in the field of algebraic topology to study shapes of datasets. It is an effective data analysis tool that is robust to noise and has been widely applied. We demonstrate a general…

Signal Processing · Electrical Eng. & Systems 2020-05-05 Yu-Min Chung , Chuan-Shen Hu , Yu-Lun Lo , Hau-Tieng Wu

Persistent homology has been studied to better understand the structural properties and topology features of weighted networks. It can reveal hidden layers of information about the higher-order structures formed by non-pairwise interactions…

Combinatorics · Mathematics 2025-06-25 Udit Raj , Slobodan Maletić , Sudeepto Bhattacharya

Identifying molecular signatures from complex disease patients with underlying symptomatic similarities is a significant challenge in the analysis of high dimensional multi-omics data. Topological data analysis (TDA) provides a way of…

Genomics · Quantitative Biology 2024-04-23 Davide Gurnari , Aldo Guzmán-Sáenz , Filippo Utro , Aritra Bose , Saugata Basu , Laxmi Parida

We present a topological pipeline for automated multiclass emotion recognition from eye-tracking data. Delay embeddings of gaze trajectories are analyzed using persistent homology. From the resulting persistence diagrams, we extract…

Machine Learning · Computer Science 2025-07-24 Arsha Niksa , Hooman Zare , Ali Shahrabi , Hanieh Hatami , Mohammadreza Razvan

This paper contains an expository account of persistent homology and its usefulness for topological data analysis. An alternative foundation for level-set persistence is presented using sheaves and cosheaves.

Algebraic Topology · Mathematics 2015-03-05 Justin Curry

Persistent homology is a central methodology in topological data analysis that has been successfully implemented in many fields and is becoming increasingly popular and relevant. The output of persistent homology is a persistence diagram --…

Statistics Theory · Mathematics 2024-04-24 Konstantin Häberle , Barbara Bravi , Anthea Monod

Modern business and economic datasets often exhibit nonlinear, multi-scale structures that traditional linear tools under-represent. Topological Data Analysis (TDA) offers a geometric lens for uncovering robust patterns, such as connected…

Machine Learning · Statistics 2025-11-18 Ioannis Diamantis

Long lived topological features are distinguished from short lived ones (considered as topological noise) in simplicial complexes constructed from complex networks. A new topological invariant, persistent homology, is determined and…

Mathematical Physics · Physics 2009-11-13 Danijela Horak , Slobodan Maletic , Milan Rajkovic

Time dependence is a universal phenomenon in nature, and a variety of mathematical models in terms of dynamical systems have been developed to understand the time-dependent behavior of real-world problems. Originally constructed to analyze…

Algebraic Topology · Mathematics 2018-02-14 Zixuan Cang , Elizabeth Munch , Guo-Wei Wei

Topological methods for data analysis present opportunities for enforcing certain invariances of broad interest in computer vision, including view-point in activity analysis, articulation in shape analysis, and measurement invariance in…

Computer Vision and Pattern Recognition · Computer Science 2018-07-30 Anirudh Som , Kowshik Thopalli , Karthikeyan Natesan Ramamurthy , Vinay Venkataraman , Ankita Shukla , Pavan Turaga

In this paper, we apply persistent entropy, a novel topological statistic, for characterization of images of epithelial tissues. We have found out that persistent entropy is able to summarize topological and geometric information encoded by…

Image and Video Processing · Electrical Eng. & Systems 2021-05-19 N. Atienza , L. M. Escudero , M. J. Jimenez , M. Soriano-Trigueros

We apply topological data analysis to the behavior of C. elegans, a widely-studied model organism in biology. In particular, we use topology to produce a quantitative summary of complex behavior which may be applied to high-throughput data.…

Algebraic Topology · Mathematics 2021-07-23 Ashleigh Thomas , Kathleen Bates , Alex Elchesen , Iryna Hartsock , Hang Lu , Peter Bubenik

This article introduces an algorithm to compute the persistent homology of a filtered complex with various coefficient fields in a single matrix reduction. The algorithm is output-sensitive in the total number of distinct persistent…

Computational Geometry · Computer Science 2020-01-10 Jean-Daniel Boissonnat , Clément Maria

Recent studies have actively employed persistent homology (PH), a topological data analysis technique, to analyze the topological information in time series data. Many successful studies have utilized graph representations of time series…

Algebraic Topology · Mathematics 2025-12-15 Eunwoo Heo , Jae-Hun Jung

Persistence has proved to be a valuable tool to analyze real world data robustly. Several approaches to persistence have been attempted over time, some topological in flavor, based on the vector space-valued homology functor, other…

Algebraic Topology · Mathematics 2019-05-23 Mattia G. Bergomi , Pietro Vertechi

Topological constraints (TCs) between polymers determine the behaviour of complex fluids such as creams, oils and plastics. Most of the polymer solutions used every day life employ linear chains; their behaviour is accurately captured by…

Soft Condensed Matter · Physics 2020-10-07 Fabio Landuzzi , Takenobu Nakamura , Davide Michieletto , Takahiro Sakaue

Computation of the simplicial complexes of a large point cloud often relies on extracting a sample, to reduce the associated computational burden. The study considers sampling critical points of a Morse function associated to a point cloud,…

Computer Vision and Pattern Recognition · Computer Science 2018-05-17 Charmin Asirimath , Jayampathy Ratnayake , Chathuranga Weeraddana

Persistent homology is a popular method for computing topological features of (metric) data. Standard approaches based on the \v{C}ech or Rips filtration are stable under small perturbations of the data, but highly sensitive to outliers.…

Algebraic Topology · Mathematics 2026-02-27 Pepijn Roos Hoefgeest , Lucas Slot
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