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Molecular crystals often exist in multiple competing polymorphs, showing significantly different physico-chemical properties. Computational crystal structure prediction is key to interpret and guide the search for the most stable or useful…

Materials Science · Physics 2016-09-16 Mariana Rossi , Piero Gasparotto , Michele Ceriotti

Assessments of machine-learned (ML) potentials are an important aspect of the rapid development of this field. We recently reported an assessment of the linear-regression permutationally invariant polynomial (PIP) method for ethanol, using…

Chemical Physics · Physics 2024-07-30 Paul L. Houston , Chen Qu , Qi Yu , Priyanka Pandey , Riccardo Conte , Apurba Nandi , Joel M. Bowman

Choice of appropriate force field is one of the main concerns of any atomistic simulation that needs to be seriously considered in order to yield reliable results. Since, investigations on mechanical behavior of materials at micro/nanoscale…

Computational Physics · Physics 2016-07-12 Seyed Moein Rassoulinejad-Mousavi , Yijin Mao , Yuwen Zhang

Here we present a computational investigation of the excited state dynamics of 5 different active medical substances (aspirin, ibuprofen, carprofen, suprofen, indomethacin) which belong to the family of nonsteroidal anti-inflammatory drugs…

Chemical Physics · Physics 2019-02-15 Neus Aguilera-Porta , Ines Corral , Jordi Munoz-Muriedas , Giovanni Granucci

We present a theoretical study of classical Wigner crystals in two- and three-dimensional isotropic parabolic traps aiming at understanding and quantifying the configurational uncertainty due to the presence of multiple stable…

Plasma Physics · Physics 2012-04-27 Arūnas Radzvilavičius , Egidijus Anisimovas

As with many parts of the natural sciences, machine learning interatomic potentials (MLIPs) are revolutionizing the modeling of molecular crystals. However, challenges remain for the accurate and efficient calculation of sublimation…

Computational Physics · Physics 2025-09-03 Flaviano Della Pia , Benjamin X. Shi , Venkat Kapil , Andrea Zen , Dario Alfè , Angelos Michaelides

The ability to reliably predict the structures and stabilities of a molecular crystal and its polymorphs without any prior experimental information would be an invaluable tool for a number of fields, with specific and immediate applications…

Conformational flexibility of molecules involved in crystal growth and dissolution is rarely investigated in detail, and usually considered to be negligible in the formulation of mesoscopic models of crystal growth. In this work we set out…

Chemical Physics · Physics 2018-07-13 Veselina Marinova , Geoffrey P. F. Wood , Ivan Marziano , Matteo Salvalaglio

Using molecular dynamics simulations, with a realistic many-body embedded-atom potential, and a novel method to characterize local order, we study the structure of pure nickel during the rapid quench of the liquid and in the resulting…

Disordered Systems and Neural Networks · Physics 2016-08-15 Oscar Rodríguez de la Fuente , José M. Soler

The fabrication of evermore sophisticated miniaturised soft robotic components made up of Electro-Active Polymers (EAPs) is constantly demanding parallel development from the in-silico simulation point of view. The incorporation of…

Soft Condensed Matter · Physics 2022-11-09 M. Horák , A. J. Gil , R. Ortigosa , M. Kružík

We study dynamics of a two-color photoassociation of atoms into diatomic molecules via nonlinear Stimulated Raman adiabatic passage (STIRAP) process. This system has a famous counterpart in (linear) quantum mechanics, and been discussed…

Other Condensed Matter · Physics 2007-12-13 A. P. Itin , S. Watanabe

In studying solidification process by simulations on the atomic scale, the modeling of crystal nucleation or amorphisation requires the construction of interatomic interactions that are able to reproduce the properties of both the solid and…

Solubility and interfacial energy are two fundamental parameters underlying the competitive nucleation of polymorphs. However, solubility measurement of metastable phases comes with a risk of solventmediated transformations which can render…

Materials Science · Physics 2023-09-15 Ruel Cedeno , Romain Grossier , Nadine Candoni , Stéphane Veesler

We apply the atom-atom potentials to molecular crystals of iron (II) complexes with bulky organic ligands. The crystals under study are formed by low-spin or high-spin molecules of Fe(phen)$_{2}$(NCS)$_{2}$ (phen = 1,10-phenanthroline),…

Crystal structure prediction (CSP) is a useful tool in pharmaceutical development for identifying and assessing risks associated with polymorphism, yet widespread adoption has been hindered by high computational costs and the need for both…

Chemical Physics · Physics 2025-07-23 Zachary L. Glick , Derek P. Metcalf , Scott F. Swarthout

Within the liquid drop model built up with the nuclear interaction parametrization Sk$\chi$450, which is based on the chiral effective field theory, we calculate numerically the internal energy density for each of nuclear pasta phases and…

Nuclear Theory · Physics 2025-09-15 Dmitry Kobyakov , Xavier Viñas

Domain structure of paracetamol -- popular antipyretic analgesic -- was investigated by infrared (IR) spectroscopy using synchrotron radiation. Absorbance and retardance maps reveal molecular orientation inside the micro-domains of the…

We study the stability of non-relativistic polytropic stars within two modified gravity theories i.e., Beyond Horndeski gravity and Eddington inspired Born Infeld theories using the configuration entropy method. We use spatially localized…

General Relativity and Quantum Cosmology · Physics 2017-12-21 C. Wibisono , A. Sulaksono

Neural network potentials trained on quantum-mechanical data can calculate molecular interactions with relatively high speed and accuracy. However, neural network potentials might exhibit instabilities, nonphysical behavior, or lack…

Computational Physics · Physics 2025-09-24 Kavindri Ranasinghe , Adam L. Baskerville , Geoffrey P. F. Wood , Gerhard Koenig

In this work we present crystal structure determination of two elusive polymorphs of furazidin, an antibacterial agent, employing a combination of crystal structure prediction (CSP) calculations and NMR crystallography approach. Two…

Chemical Physics · Physics 2020-08-07 Marta K. Dudek , Piotr Paluch , Edyta Pindelska
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