English
Related papers

Related papers: Density estimation for ordinal biological sequence…

200 papers

The ordinal patterns of a fixed number of consecutive values in a time series is the spatial ordering of these values. Counting how often a specific ordinal pattern occurs in a time series provides important insights into the properties of…

Statistics Theory · Mathematics 2025-02-06 Annika Betken , Giorgio Micali , Johannes Schmidt-Hieber

In this paper the elicitation of probabilities from human experts is considered as a measurement process, which may be disturbed by random 'measurement noise'. Using Bayesian concepts a second order probability distribution is derived…

Artificial Intelligence · Computer Science 2013-04-05 Gerhard Paaß

Sequential neuronal activity underlies a wide range of processes in the brain. Neuroscientific evidence for neuronal sequences has been reported in domains as diverse as perception, motor control, speech, spatial navigation and memory.…

Adaptation and Self-Organizing Systems · Physics 2020-04-03 Sascha Frölich , Dimitrije Marković , Stefan J. Kiebel

Selection bias arises when the probability that an observation enters a dataset depends on variables related to the quantities of interest, leading to systematic distortions in estimation and uncertainty quantification. For example, in…

We present a new Bayesian methodology to learn the unknown material density of a given sample by inverting its two-dimensional images that are taken with a Scanning Electron Microscope. An image results from a sequence of projections of the…

Applications · Statistics 2014-03-06 Dalia Chakrabarty , Fabio Rigat , Nare Gabrielyan , Richard Beanland , Shashi Paul

Anomaly detection is a well-established field in machine learning, identifying observations that deviate from typical patterns. The principles of anomaly detection could enhance our understanding of how biological systems recognize and…

Populations and Evolution · Quantitative Biology 2025-10-30 Steven A. Frank

Deep generative models for anomaly detection in multivariate time-series are typically trained by maximizing data likelihood. However, likelihood in observation space measures marginal density rather than conformity to structured temporal…

Artificial Intelligence · Computer Science 2026-03-13 David Baumgartner , Eliezer de Souza da Silva , Iñigo Urteaga

In this paper, we present a novel approach to accelerate the Bayesian inference process, focusing specifically on the nested sampling algorithms. Bayesian inference plays a crucial role in cosmological parameter estimation, providing a…

Instrumentation and Methods for Astrophysics · Physics 2024-10-17 Isidro Gómez-Vargas , J. Alberto Vázquez

Complex systems, ranging from soft materials to wireless communication, are often organised as random geometric networks in which nodes and edges evenly fill up the volume of some space. Studying such networks is difficult because they…

Probability · Mathematics 2022-07-19 Ivan Kryven , Rik Versendaal

While the study of a single network is well-established, technological advances now allow for the collection of multiple networks with relative ease. Increasingly, anywhere from several to thousands of networks can be created from brain…

Applications · Statistics 2021-01-14 Nathaniel Josephs , Lizhen Lin , Steven Rosenberg , Eric D. Kolaczyk

We propose a novel Bayesian methodology which uses random walks for rapid inference of statistical properties of undirected networks with weighted or unweighted edges. Our formalism yields high-accuracy estimates of the probability…

Physics and Society · Physics 2018-07-25 Willow B. Kion-Crosby , Alexandre V. Morozov

With a view to connecting random mutation on the molecular level to punctuated equilibrium behavior on the phenotype level, we propose a new model for biological evolution, which incorporates random mutation and natural selection. In this…

Condensed Matter · Physics 2009-10-28 M. Y. Choi , H. Y. Lee , D. Kim , S. H. Park

We present a nonparametric framework to model a short sequence of probability distributions that vary both due to underlying effects of sequential progression and confounding noise. To distinguish between these two types of variation and…

Methodology · Statistics 2019-02-08 Jonas Mueller , Tommi Jaakkola , David Gifford

Sequential probabilistic inference from streaming observations requires modeling distributions over future trajectories as new observations arrive. Although diffusion and flow-matching models are effective at capturing high-dimensional,…

Machine Learning · Computer Science 2026-05-15 Yinan Huang , Hans Hao-Hsun Hsu , Junran Wang , Bo Dai , Pan Li

One thing that discriminates living things from inanimate matter is their ability to generate similarly complex or non-random architectures in a large abundance. From DNA sequences to folded protein structures, living cells, microbial…

Other Quantitative Biology · Quantitative Biology 2018-02-07 Stuart M. Marshall , Alastair R. G. Murray , Leroy Cronin

A Bayesian non-parametric framework for studying time-to-event data is proposed, where the prior distribution is allowed to depend on an additional random source, and may update with the sample size. Such scenarios are natural, for…

Methodology · Statistics 2025-05-06 Martin Bladt , Jorge González Cázares

In many biological processes heterogeneity within cell populations is an important issue. In this work we consider populations where the behavior of every single cell can be described by a system of ordinary differential equations.…

Molecular Networks · Quantitative Biology 2010-02-25 J. Hasenauer , S. Waldherr , M. Doszczak , P. Scheurich , F. Allgower

Measurement in biological systems became a subject of concern as a consequence of numerous reports on limited reproducibility of experimental results. To reveal origins of this inconsistency, we have examined general features of biological…

Other Quantitative Biology · Quantitative Biology 2017-04-03 Dalibor Štys , Jan Urban , Renata Rychtáriková , Anna Zhyrova , Petr Císař

Transcription is a complex phenomenon that permits the conversion of genetic information into phenotype by means of an enzyme called RNA polymerase, which erratically moves along and scans the DNA template. We perform Bayesian inference…

Biological Physics · Physics 2023-07-18 Massimo Cavallaro , Yuexuan Wang , Daniel Hebenstreit , Ritabrata Dutta

We consider inference from non-random samples in data-rich settings where high-dimensional auxiliary information is available both in the sample and the target population, with survey inference being a special case. We propose a regularized…

Methodology · Statistics 2021-04-13 Yutao Liu , Andrew Gelman , Qixuan Chen