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In the application of deep learning on optical coherence tomography (OCT) data, it is common to train classification networks using 2D images originating from volumetric data. Given the micrometer resolution of OCT systems, consecutive…

Image and Video Processing · Electrical Eng. & Systems 2022-09-29 Iulian Emil Tampu , Anders Eklund , Neda Haj-Hosseini

Machine learning (ML) approaches to data analysis are now widely adopted in many fields including epidemiology and medicine. To apply these approaches, confounds must first be removed as is commonly done by featurewise removal of their…

As the scale and size of the data increases significantly nowadays, federal learning (Bonawitz et al. [2019]) for high performance computing and machine learning has been much more important than ever before (Abadi et al. [2016]). People…

Machine Learning · Computer Science 2022-11-16 Yanchong Zheng

Deep learning is catalyzing a scientific revolution fueled by big data, accessible toolkits, and powerful computational resources, impacting many fields including protein structural modeling. Protein structural modeling, such as predicting…

Biomolecules · Quantitative Biology 2020-07-17 Wenhao Gao , Sai Pooja Mahajan , Jeremias Sulam , Jeffrey J. Gray

In post genomic era with the advent of new technologies a huge amount of complex molecular data are generated with high throughput. The management of this biological data is definitely a challenging task due to complexity and heterogeneity…

Databases · Computer Science 2014-03-13 Ananya Bose , Suprativ Saha

Classical machine learning algorithms often face scalability bottlenecks when they are applied to large-scale data. Such algorithms were designed to work with small data that is assumed to fit in the memory of one machine. In this report,…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-05-14 Tarek Elgamal , Mohamed Hefeeda

Protein is linked to almost every life process. Therefore, analyzing the biological structure and property of protein sequences is critical to the exploration of life, as well as disease detection and drug discovery. Traditional protein…

Machine Learning · Computer Science 2021-12-08 Yijia Xiao , Jiezhong Qiu , Ziang Li , Chang-Yu Hsieh , Jie Tang

In collaborative learning, clients keep their data private and communicate only the computed gradients of the deep neural network being trained on their local data. Several recent attacks show that one can still extract private information…

Machine Learning · Computer Science 2022-07-26 Fan Mo , Anastasia Borovykh , Mohammad Malekzadeh , Soteris Demetriou , Deniz Gündüz , Hamed Haddadi

The performance of machine learning algorithms heavily relies on the availability of a large amount of training data. However, in reality, data usually reside in distributed parties such as different institutions and may not be directly…

Machine Learning · Computer Science 2021-04-15 Maoguo Gong , Yuan Gao , Yu Xie , A. K. Qin , Ke Pan , Yew-Soon Ong

The breakthrough in Deep Learning neural networks has transformed the use of AI and machine learning technologies for the analysis of very large experimental datasets. These datasets are typically generated by large-scale experimental…

Machine Learning · Computer Science 2021-10-26 Jeyan Thiyagalingam , Mallikarjun Shankar , Geoffrey Fox , Tony Hey

With the advent of high-throughput wet lab technologies the amount of protein interaction data available publicly has increased substantially, in turn spurring a plethora of computational methods for in silico knowledge discovery from this…

Molecular Networks · Quantitative Biology 2015-05-06 Sriganesh Srihari , Hon Wai Leong

Geometric deep learning has recently achieved great success in non-Euclidean domains, and learning on 3D structures of large biomolecules is emerging as a distinct research area. However, its efficacy is largely constrained due to the…

Machine Learning · Computer Science 2023-10-31 Fang Wu , Lirong Wu , Dragomir Radev , Jinbo Xu , Stan Z. Li

Even though a train/test split of the dataset randomly performed is a common practice, could not always be the best approach for estimating performance generalization under some scenarios. The fact is that the usual machine learning…

Machine Learning · Computer Science 2022-09-09 Carlos Catania , Jorge Guerra , Juan Manuel Romero , Gabriel Caffaratti , Martin Marchetta

Recommendation has become a prominent area of research in the field of Information Retrieval (IR). Evaluation is also a traditional research topic in this community. Motivated by a few counter-intuitive observations reported in recent…

Information Retrieval · Computer Science 2023-08-22 Aixin Sun

Privacy-Preserving machine learning (PPML) can help us train and deploy models that utilize private information. In particular, on-device machine learning allows us to avoid sharing raw data with a third-party server during inference.…

Machine Learning · Computer Science 2024-01-23 Xinchi Qiu , Ilias Leontiadis , Luca Melis , Alex Sablayrolles , Pierre Stock

With the extensive use of machine learning technologies, data providers encounter increasing privacy risks. Recent legislation, such as GDPR, obligates organizations to remove requested data and its influence from a trained model. Machine…

Computers and Society · Computer Science 2024-11-07 Hengzhu Liu , Tianqing Zhu , Lefeng Zhang , Ping Xiong

Recent research demonstrated that training large language models involves memorization of a significant fraction of training data. Such memorization can lead to privacy violations when training on sensitive user data and thus motivates the…

Machine Learning · Computer Science 2025-10-29 Vitaly Feldman , Guy Kornowski , Xin Lyu

Motivation: Machine learning based prediction of compound-protein interactions (CPIs) is important for drug design, screening and repurposing studies and can improve the efficiency and cost-effectiveness of wet lab assays. Despite the…

Quantitative Methods · Quantitative Biology 2022-02-02 Adiba Yaseen , Imran Amin , Naeem Akhter , Asa Ben-Hur , Fayyaz Minhas

In recent years, machine learning techniques are widely used in numerous applications, such as weather forecast, financial data analysis, spam filtering, and medical prediction. In the meantime, massive data generated from multiple sources…

Cryptography and Security · Computer Science 2018-10-08 Wei Du , Ang Li , Qinghua Li

Training deep neural networks via federated learning allows clients to share, instead of the original data, only the model trained on their data. Prior work has demonstrated that in practice a client's private information, unrelated to the…

Cryptography and Security · Computer Science 2021-06-01 Fan Mo , Anastasia Borovykh , Mohammad Malekzadeh , Hamed Haddadi , Soteris Demetriou