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Accurate image registration is essential in many medical imaging applications, yet most deep registration networks provide little indication of when or where their predictions are unreliable. Existing uncertainty estimation approaches, such…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Lin Tian , Xiaoling Hu , Juan Eugenio Iglesias

We propose a registration algorithm for 2D CT/MRI medical images with a new unsupervised end-to-end strategy using convolutional neural networks. The contributions of our algorithm are threefold: (1) We transplant traditional image…

Computer Vision and Pattern Recognition · Computer Science 2018-01-23 Siyuan Shan , Wen Yan , Xiaoqing Guo , Eric I-Chao Chang , Yubo Fan , Yan Xu

Prostate cancer is a leading cause of cancer-related mortality in men. The registration of magnetic resonance (MR) and transrectal ultrasound (TRUS) can provide guidance for the targeted biopsy of prostate cancer. In this study, we propose…

Image and Video Processing · Electrical Eng. & Systems 2025-01-08 Zetian Feng , Dong Ni , Yi Wang

Cervical adenocarcinoma in situ (AIS) is a critical premalignant lesion whose accurate histopathological diagnosis is challenging. Early detection is essential to prevent progression to invasive cervical adenocarcinoma. In this study, we…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Gabriela Fernandes

While the Gleason score is the most important prognostic marker for prostate cancer patients, it suffers from significant observer variability. Artificial Intelligence (AI) systems, based on deep learning, have proven to achieve…

Background: Multiparametric breast MRI data might improve tumor diagnostics, characterization, and treatment planning. Accurate alignment and delineation of images acquired at different field strengths such as 3T and 7T, remain challenging…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Muhammad Shahkar Khan , Haider Ali , Laura Villazan Garcia , Noor Badshah , Siegfried Trattnig , Florian Schwarzhans , Ramona Woitek , Olgica Zaric

Magnetic Resonance Imaging (MRI) is widely used for screening and staging prostate cancer. However, many prostate cancers have subtle features which are not easily identifiable on MRI, resulting in missed diagnoses and alarming variability…

Advances in deep learning for natural images have prompted a surge of interest in applying similar techniques to medical images. The majority of the initial attempts focused on replacing the input of a deep convolutional neural network with…

Computer Vision and Pattern Recognition · Computer Science 2018-06-29 Krzysztof J. Geras , Stacey Wolfson , Yiqiu Shen , Nan Wu , S. Gene Kim , Eric Kim , Laura Heacock , Ujas Parikh , Linda Moy , Kyunghyun Cho

We describe a diffeomorphic registration algorithm that allows groups of images to be accurately aligned to a common space, which we intend to incorporate into the SPM software. The idea is to perform inference in a probabilistic graphical…

Computer Vision and Pattern Recognition · Computer Science 2021-05-10 Mikael Brudfors , Yaël Balbastre , Guillaume Flandin , Parashkev Nachev , John Ashburner

Image registration is an ill-posed inverse problem which often requires regularisation on the solution space. In contrast to most of the current approaches which impose explicit regularisation terms such as smoothness, in this paper we…

Image and Video Processing · Electrical Eng. & Systems 2020-07-09 Chen Qin , Shuo Wang , Chen Chen , Huaqi Qiu , Wenjia Bai , Daniel Rueckert

Cancerous skin lesions are one of the most common malignancies detected in humans, and if not detected at an early stage, they can lead to death. Therefore, it is crucial to have access to accurate results early on to optimize the chances…

Image and Video Processing · Electrical Eng. & Systems 2023-05-19 Daniel Alonso Villanueva Nunez , Yongmin Li

Deep learning-based methods have recently demonstrated promising results in deformable image registration for a wide range of medical image analysis tasks. However, existing deep learning-based methods are usually limited to small…

Image and Video Processing · Electrical Eng. & Systems 2020-07-01 Tony C. W. Mok , Albert C. S. Chung

Deformable image registration is one of the fundamental tasks in medical imaging. Classical registration algorithms usually require a high computational cost for iterative optimizations. Although deep-learning-based methods have been…

Image and Video Processing · Electrical Eng. & Systems 2022-09-30 Boah Kim , Inhwa Han , Jong Chul Ye

Diffusion-weighted magnetic resonance imaging (DW-MRI) is a non-invasive way of imaging white matter tracts in the human brain. DW-MRIs are usually acquired using echo-planar imaging (EPI) with high gradient fields, which could introduce…

Image and Video Processing · Electrical Eng. & Systems 2023-04-04 Zhangxing Bian , Muhan Shao , Aaron Carass , Jerry L. Prince

Data from a multi-parametric MRI study of patients with possible early-stage prostate cancer was assessed with a view to creating an efficient clinical protocol. Based on a correlation analysis suggesting that diffusion-weighted imaging…

Medical Physics · Physics 2017-11-28 Ioannis Papadopoulos , Jonathan Phillips , Rhodri Evans , Neil Fenn , Sophie Schermer

Deformable image registration is a fundamental task in medical image analysis, aiming to establish a dense and non-linear correspondence between a pair of images. Previous deep-learning studies usually employ supervised neural networks to…

Computer Vision and Pattern Recognition · Computer Science 2018-09-11 Jun Zhang

Deep learning technologies have dramatically reshaped the field of medical image registration over the past decade. The initial developments, such as regression-based and U-Net-based networks, established the foundation for deep learning in…

Image and Video Processing · Electrical Eng. & Systems 2024-11-04 Junyu Chen , Yihao Liu , Shuwen Wei , Zhangxing Bian , Shalini Subramanian , Aaron Carass , Jerry L. Prince , Yong Du

Deformable image registration is crucial for aligning medical images in a nonlinear fashion across different modalities, allowing for precise spatial correspondence between varying anatomical structures. This paper presents NestedMorph, a…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Gurucharan Marthi Krishna Kumar , Janine Mendola , Amir Shmuel

Image registration is a key operation in medical image processing, allowing a plethora of applications. Mutual information (MI) is consolidated as a robust similarity metric often used for medical image registration. Although MI provides a…

Image and Video Processing · Electrical Eng. & Systems 2020-12-01 Vinicius Pavanelli Vianna , Luiz Otavio Murta

The recent application of deep learning technologies in medical image registration has exponentially decreased the registration time and gradually increased registration accuracy when compared to their traditional counterparts. Most of the…

Image and Video Processing · Electrical Eng. & Systems 2020-02-19 Abdullah Nazib , Clinton Fookes , Olivier Salvado , Dimitri Perrin