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To our knowledge, all deep computer-aided detection and diagnosis (CAD) systems for prostate cancer (PCa) detection consider bi-parametric magnetic resonance imaging (bp-MRI) only, including T2w and ADC sequences while excluding the 4D…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Audrey Duran , Gaspard Dussert , Carole Lartizien

This paper presents a novel predictive model, MetaMorph, for metamorphic registration of images with appearance changes (i.e., caused by brain tumors). In contrast to previous learning-based registration methods that have little or no…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Jian Wang , Jiarui Xing , Jason Druzgal , William M. Wells , Miaomiao Zhang

Biparametric MRI has emerged as an alternative to multiparametric prostate MRI, which eliminates the need for the potential harms to the patient due to the contrast medium. One major issue with biparametric MRI is difficulty to detect…

Breast cancer was diagnosed for over 7.8 million women between 2015 to 2020. Grading plays a vital role in breast cancer treatment planning. However, the current tumor grading method involves extracting tissue from patients, leading to…

Image and Video Processing · Electrical Eng. & Systems 2024-05-14 Chi-en Amy Tai , Alexander Wong

Numerous regularization methods for deformable image registration aim at enforcing smooth transformations, but are difficult to tune-in a priori and lack a clear physical basis. Physically inspired strategies have emerged, offering a sound…

Image and Video Processing · Electrical Eng. & Systems 2023-12-27 Pablo Alvarez , Stéphane Cotin

Purpose: To investigate feasibility of accelerating prostate diffusion-weighted imaging (DWI) by reducing the number of acquired averages and denoising the resulting image using a proposed guided denoising convolutional neural network…

Image and Video Processing · Electrical Eng. & Systems 2020-07-02 Elena A. Kaye , Emily A. Aherne , Cihan Duzgol , Ida Häggström , Erich Kobler , Yousef Mazaheri , Maggie M Fung , Zhigang Zhang , Ricardo Otazo , Herbert A. Vargas , Oguz Akin

Machine learning (ML) systems for medical imaging have demonstrated remarkable diagnostic capabilities, but their susceptibility to biases poses significant risks, since biases may negatively impact generalization performance. In this…

Machine Learning · Computer Science 2025-04-29 Haroui Ma , Francesco Quinzan , Theresa Willem , Stefan Bauer

Neural networks have been proposed for medical image registration by learning, with a substantial amount of training data, the optimal transformations between image pairs. These trained networks can further be optimized on a single pair of…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Zachary MC Baum , Yipeng Hu , Dean C Barratt

We propose an image synthesis mechanism for multi-sequence prostate MR images conditioned on text, to control lesion presence and sequence, as well as to generate paired bi-parametric images conditioned on images e.g. for generating…

Image and Video Processing · Electrical Eng. & Systems 2023-03-06 Shaheer U. Saeed , Tom Syer , Wen Yan , Qianye Yang , Mark Emberton , Shonit Punwani , Matthew J. Clarkson , Dean C. Barratt , Yipeng Hu

Image registration is the inference of transformations relating noisy and distorted images. It is fundamental in computer vision, experimental physics, and medical imaging. Many algorithms and analyses exist for inferring shift, rotation,…

Data Analysis, Statistics and Probability · Physics 2019-02-21 Colin B. Clement , Matthew Bierbaum , James P. Sethna

Artificial Intelligence (AI) based image analysis has an immense potential to support diagnostic histopathology, including cancer diagnostics. However, developing supervised AI methods requires large-scale annotated datasets. A potentially…

Quantitative assessment of treatment response in Advanced Prostate Cancer (APC) with bone metastases remains an unmet clinical need. Whole-Body Diffusion-Weighted MRI (WB-DWI) provides two response biomarkers: Total Diffusion Volume (TDV)…

Affine image registration is a cornerstone of medical image analysis. While classical algorithms can achieve excellent accuracy, they solve a time-consuming optimization for every image pair. Deep-learning (DL) methods learn a function that…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Malte Hoffmann , Andrew Hoopes , Douglas N. Greve , Bruce Fischl , Adrian V. Dalca

Effective transperineal ultrasound image guidance in prostate external beam radiotherapy requires consistent alignment between probe and prostate at each session during patient set-up. Probe placement and ultrasound image inter-pretation…

Computer Vision and Pattern Recognition · Computer Science 2020-10-07 Alexander Grimwood , Helen McNair , Yipeng Hu , Ester Bonmati , Dean Barratt , Emma Harris

Deformable medical image registration is a fundamental task in medical image analysis. While deep learning-based methods have demonstrated superior accuracy and computational efficiency compared to traditional techniques, they often…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Ahsan Raza Siyal , Markus Haltmeier , Ruth Steiger , Malik Galijasevic , Elke Ruth Gizewski , Astrid Ellen Grams

Breast cancer screening with mammography remains central to early detection and mortality reduction. Deep learning has shown strong potential for automating mammogram interpretation, yet limited-resolution datasets and small sample sizes…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Farbod Bigdeli , Mohsen Mohammadagha , Ali Bigdeli

Recent deep learning-based methods have shown promising results and runtime advantages in deformable image registration. However, analyzing the effects of hyperparameters and searching for optimal regularization parameters prove to be too…

Computer Vision and Pattern Recognition · Computer Science 2021-07-06 Tony C. W. Mok , Albert C. S. Chung

Classical deformable registration techniques achieve impressive results and offer a rigorous theoretical treatment, but are computationally intensive since they solve an optimization problem for each image pair. Recently, learning-based…

Computer Vision and Pattern Recognition · Computer Science 2019-07-26 Adrian V. Dalca , Guha Balakrishnan , John Guttag , Mert R. Sabuncu

Image registration, the process of aligning two or more images, is the core technique of many (semi-)automatic medical image analysis tasks. Recent studies have shown that deep learning methods, notably convolutional neural networks…

Computer Vision and Pattern Recognition · Computer Science 2021-09-09 Bob D. de Vos , Floris F. Berendsen , Max A. Viergever , Hessam Sokooti , Marius Staring , Ivana Isgum

Prostate cancer is one of the most common forms of cancer and the third leading cause of cancer death in North America. As an integrated part of computer-aided detection (CAD) tools, diffusion-weighted magnetic resonance imaging (DWI) has…

Computer Vision and Pattern Recognition · Computer Science 2020-06-11 Sunghwan Yoo , Isha Gujrathi , Masoom A. Haider , Farzad Khalvati
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