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This paper explores uncertainty quantification (UQ) as an indicator of the trustworthiness of automated deep-learning (DL) tools in the context of white matter lesion (WML) segmentation from magnetic resonance imaging (MRI) scans of…

Despite the remarkable success on medical image analysis with deep learning, it is still under exploration regarding how to rapidly transfer AI models from one dataset to another for clinical applications. This paper presents a novel and…

Computer Vision and Pattern Recognition · Computer Science 2022-04-14 Wenao Ma , Shuang Zheng , Lei Zhang , Huimao Zhang , Qi Dou

Technological and computational advances continuously drive forward the broad field of deep learning. In recent years, the derivation of quantities describing theuncertainty in the prediction - which naturally accompanies the modeling…

Machine Learning · Computer Science 2022-05-31 Christoph Koller , Göran Kauermann , Xiao Xiang Zhu

Generalization is one of the key challenges in the clinical validation and application of deep learning models to medical images. Studies have shown that such models trained on publicly available datasets often do not work well on…

Computer Vision and Pattern Recognition · Computer Science 2020-03-04 Yu Zhang , Gongbo Liang , Nathan Jacobs , Xiaoqin Wang

Clinical decision support using deep neural networks has become a topic of steadily growing interest. While recent work has repeatedly demonstrated that deep learning offers major advantages for medical image classification over traditional…

Image and Video Processing · Electrical Eng. & Systems 2022-06-10 Alexander Katzmann , Oliver Taubmann , Stephen Ahmad , Alexander Mühlberg , Michael Sühling , Horst-Michael Groß

Biological systems are governed by structured molecular interactions, where pathways, regulatory circuits, and functional gene relationships shape cellular behavior and disease progression. Much of this knowledge is naturally represented as…

Machine Learning · Computer Science 2026-05-26 Yuwei Xue , Sakib Mostafa , James Zou , Joseph Liao , Maximilian Diehn , Ash A. Alizadeh , Lei Xing , Md. Tauhidul Islam

Measuring cross-sectional areas in ultrasound images is a standard tool to evaluate disease progress or treatment response. Often addressed today with supervised deep-learning segmentation approaches, existing solutions highly depend upon…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Vanessa Gonzalez Duque , Leonhard Zirus , Yordanka Velikova , Nassir Navab , Diana Mateus

Edge learning refers to training machine learning models deployed on edge platforms, typically using new data accumulated onboard. The computational limitations on edge devices affect not only model optimisation, but also calculation of the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Anh Vu Nguyen , Dino Sejdinovic , Tat-Jun Chin

Efficient intravascular access in trauma and critical care significantly impacts patient outcomes. However, the availability of skilled medical personnel in austere environments is often limited. Autonomous robotic ultrasound systems can…

Computer Vision and Pattern Recognition · Computer Science 2024-08-01 Rohini Banerjee , Cecilia G. Morales , Artur Dubrawski

Organ segmentation in CT volumes is an important pre-processing step in many computer assisted intervention and diagnosis methods. In recent years, convolutional neural networks have dominated the state of the art in this task. However,…

Image and Video Processing · Electrical Eng. & Systems 2020-12-08 Roger D. Soberanis-Mukul , Nassir Navab , Shadi Albarqouni

Plant seedling segmentation supports automated phenotyping in precision agriculture. Standard segmentation models face difficulties due to intricate background images and fine structures in leaves. We introduce UGDA-Net (Uncertainty-Guided…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Mohamed Ehab , Ali Hamdi

While deep learning methods hitherto have achieved considerable success in medical image segmentation, they are still hampered by two limitations: (i) reliance on large-scale well-labeled datasets, which are difficult to curate due to the…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 Ziyuan Zhao , Fangcheng Zhou , Kaixin Xu , Zeng Zeng , Cuntai Guan , S. Kevin Zhou

A model's ability to express its own predictive uncertainty is an essential attribute for maintaining clinical user confidence as computational biomarkers are deployed into real-world medical settings. In the domain of cancer digital…

Fully automatic deep learning has become the state-of-the-art technique for many tasks including image acquisition, analysis and interpretation, and for the extraction of clinically useful information for computer-aided detection,…

Machine Learning · Computer Science 2021-05-06 Samuel Budd , Emma C Robinson , Bernhard Kainz

Deep-learning-based pipelines have shown the potential to revolutionalize microscopy image diagnostics by providing visual augmentations to a trained pathology expert. However, to match human performance, the methods rely on the…

Accurate vessel segmentation is essential for medical image analysis, yet remains challenging due to complex vascular patterns and imaging ambiguity. Most deep models rely on single-pass prediction, limiting their ability to refine…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Huan Huang , Michele Esposito , Chen Zhao

Artificial intelligence (AI) systems accelerate medical workflows and improve diagnostic accuracy in healthcare, serving as second-opinion systems. However, the unpredictability of AI errors poses a significant challenge, particularly in…

To be effective, state of the art machine learning technology needs large amounts of annotated data. There are numerous compelling applications in healthcare that can benefit from high performance automated decision support systems provided…

Signal Processing · Electrical Eng. & Systems 2018-01-09 Scott Yang , Silvia Lopez , Meysam Golmohammadi , Iyad Obeid , Joseph Picone

Medical image segmentation modeling is a high-stakes task where understanding of uncertainty is crucial for addressing visual ambiguity. Prior work has developed segmentation models utilizing probabilistic or generative mechanisms to infer…

Computer Vision and Pattern Recognition · Computer Science 2025-06-13 Andre Ye , Quan Ze Chen , Amy Zhang