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Discrimination measures such as the concordance index and the cumulative-dynamic time-dependent area under the ROC-curve (AUC) are widely used in the medical literature for evaluating the predictive accuracy of a scoring rule which relates…

Methodology · Statistics 2025-08-12 Marie Skov Breum , Torben Martinussen

We consider an online learning problem in environments with multiple change points. In contrast to the single change point problem that is widely studied using classical "high confidence" detection schemes, the multiple change point…

Machine Learning · Statistics 2026-02-13 Tomer Gafni , Garud Iyengar , Assaf Zeevi

Complex survey data are usually collected following complex sampling designs. Accounting for the sampling design is essential to obtain unbiased estimates and valid inferences when analyzing complex survey data. The area under the receiver…

Methodology · Statistics 2026-03-31 Amaia Iparragirre , Thomas Lumley , Irantzu Barrio

In a binary classification problem the feature vector (predictor) is the input to a scoring function that produces a decision value (score), which is compared to a particular chosen threshold to provide a final class prediction (output).…

Machine Learning · Computer Science 2021-11-11 Waleed A. Yousef

The area under the curve (AUC) of the mean cumulative function (MCF) has recently been introduced as a novel estimand for evaluating treatment effects in recurrent event settings, offering an alternative to the commonly used…

Methodology · Statistics 2025-07-22 Jiren Sun , Tuo Wang , Yanyao Yi , Ting Ye , Jun Shao , Yu Du

Popularity bias is a persistent issue associated with recommendation systems, posing challenges to both fairness and efficiency. Existing literature widely acknowledges that reducing popularity bias often requires sacrificing recommendation…

Information Retrieval · Computer Science 2023-06-05 Bin Liu , Erjia Chen , Bang Wang

Attributed Graph Clustering (AGC) is a fundamental unsupervised task that partitions nodes into cohesive groups by jointly modeling structural topology and node attributes. While the advent of graph neural networks and self-supervised…

Machine Learning · Computer Science 2026-03-24 Yunhui Liu , Yue Liu , Yongchao Liu , Tao Zheng , Stan Z. Li , Xinwang Liu , Tieke He

Ad ranking systems must simultaneously optimize multiple objectives including click-through rate (CTR), conversion rate (CVR), revenue, and user experience metrics. However, production systems face critical challenges: score scale…

Machine Learning · Computer Science 2026-02-24 Xikai Yang , Sebastian Sun , Yilin Li , Yue Xing , Ming Wang , Yang Wang

Area under the receiver operating characteristics curve (AUC) is an important metric for a wide range of signal processing and machine learning problems, and scalable methods for optimizing AUC have recently been proposed. However, handling…

Machine Learning · Computer Science 2018-06-01 San Gultekin , Avishek Saha , Adwait Ratnaparkhi , John Paisley

Background: Despite high in-silico performance (AUC >0.80), 85% of AI cancer biomarkers fail clinical translation, exposing a critical algorithm-to-outcome gap. Methods: We introduce the Algorithm-to-Outcome Concordance (AOC) framework,…

Quantitative Methods · Quantitative Biology 2026-01-06 Xiyao Yu , Kai Fu

Objective: Area under the receiving operator characteristic curve (AUC) is commonly reported alongside prediction models for binary outcomes. Recent articles have raised concerns that AUC might be a misleading measure of prediction…

Machine Learning · Statistics 2025-11-04 Emily Minus , R. Yates Coley , Susan M. Shortreed , Brian D. Williamson

Link prediction is a paradigmatic and challenging problem in network science, which attempts to uncover missing links or predict future links, based on known topology. A fundamental but still unsolved issue is how to choose proper metrics…

Data Analysis, Statistics and Probability · Physics 2023-03-22 Tao Zhou

The development of causal prediction models is challenged by the fact that the outcome is only observable for the applied (factual) intervention and not for its alternatives (the so-called counterfactuals); in medicine we only know…

Machine Learning · Computer Science 2023-11-29 Stefan Schrod , Fabian Sinz , Michael Altenbuchinger

An agnostic PAC learning algorithm finds a predictor that is competitive with the best predictor in a benchmark hypothesis class, where competitiveness is measured with respect to a given loss function. However, its predictions might be…

Machine Learning · Computer Science 2021-05-24 Guy N Rothblum , Gal Yona

Selecting an evaluation metric is fundamental to model development, but uncertainty remains about when certain metrics are preferable and why. This paper introduces the concept of *resolving power* to describe the ability of an evaluation…

Methodology · Statistics 2025-02-07 Colin S. Beam

The statistics community, which has traditionally lacked a transparent and open peer-review system, faces a challenge of inconsistent paper quality, with some published work containing substantial errors. This problem resonates with…

Methodology · Statistics 2025-12-10 Zhen Li

Reliable uncertainty estimation is one of the major challenges for medical classification tasks. While many approaches have been proposed, recently the statistical framework of conformal predictions has gained a lot of attention, due to its…

Machine Learning · Computer Science 2025-06-24 Hendrik Mehrtens , Tabea Bucher , Titus J. Brinker

Medical multimodal learning faces significant challenges with missing modalities prevalent in clinical practice. Existing approaches assume equal contribution of modality and random missing patterns, neglecting inherent uncertainty in…

Machine Learning · Computer Science 2026-01-30 Linxiao Gong , Yang Liu , Lianlong Sun , Yulai Bi , Jing Liu , Xiaoguang Zhu

AUC is an important performance measure and many algorithms have been devoted to AUC optimization, mostly by minimizing a surrogate convex loss on a training data set. In this work, we focus on one-pass AUC optimization that requires only…

Machine Learning · Computer Science 2020-07-07 Wei Gao , Rong Jin , Shenghuo Zhu , Zhi-Hua Zhou

Bayesian approaches for handling covariate measurement error are well established, and yet arguably are still relatively little used by researchers. For some this is likely due to unfamiliarity or disagreement with the Bayesian inferential…

Methodology · Statistics 2017-08-01 Jonathan W. Bartlett , Ruth H. Keogh