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In today's data-driven digital era, the amount as well as complexity, such as multi-view, non-Euclidean, and multi-relational, of the collected data are growing exponentially or even faster. Clustering, which unsupervisely extracts valid…

Machine Learning · Computer Science 2025-01-10 Zhao Kang , Xuanting Xie , Bingheng Li , Erlin Pan

Single-cell RNA sequencing (scRNA-seq) enables the study of cellular diversity at single cell level. It provides a global view of cell-type specification during the onset of biological mechanisms such as developmental processes and human…

Machine Learning · Computer Science 2025-11-05 Muhammad Umar , Andras Lakatos , Muhammad Asif , Arif Mahmood

Deep convolutional neural networks (CNNs) have dominated many computer vision domains because of their great power to extract good features automatically. However, many deep CNNs-based computer vison tasks suffer from lack of training data…

Computer Vision and Pattern Recognition · Computer Science 2018-08-21 Jie Guo , Tingfa Xu , Shenwang Jiang , Ziyi Shen

Stochastic Gradient Decent (SGD) is one of the core techniques behind the success of deep neural networks. The gradient provides information on the direction in which a function has the steepest rate of change. The main problem with basic…

Deep graph clustering, which aims to group nodes into disjoint clusters by neural networks in an unsupervised manner, has attracted great attention in recent years. Although the performance has been largely improved, the excellent…

Machine Learning · Computer Science 2023-08-15 Yue Liu , Ke Liang , Jun Xia , Xihong Yang , Sihang Zhou , Meng Liu , Xinwang Liu , Stan Z. Li

With recent advancing of Internet of Things (IoTs), it becomes very attractive to implement the deep convolutional neural networks (DCNNs) onto embedded/portable systems. Presently, executing the software-based DCNNs requires…

Computer Vision and Pattern Recognition · Computer Science 2017-02-01 Ao Ren , Ji Li , Zhe Li , Caiwen Ding , Xuehai Qian , Qinru Qiu , Bo Yuan , Yanzhi Wang

Given entities and their interactions in the web data, which may have occurred at different time, how can we find communities of entities and track their evolution? In this paper, we approach this important task from graph clustering…

Social and Information Networks · Computer Science 2023-03-29 Namyong Park , Ryan Rossi , Eunyee Koh , Iftikhar Ahamath Burhanuddin , Sungchul Kim , Fan Du , Nesreen Ahmed , Christos Faloutsos

Capturing global contextual representations by exploiting long-range pixel-pixel dependencies has shown to improve semantic segmentation performance. However, how to do this efficiently is an open question as current approaches of utilising…

Computer Vision and Pattern Recognition · Computer Science 2021-01-05 Qinghui Liu , Michael Kampffmeyer , Robert Jenssen , Arnt-Børre Salberg

The Graph Convolutional Network (GCN) model and its variants are powerful graph embedding tools for facilitating classification and clustering on graphs. However, a major challenge is to reduce the complexity of layered GCNs and make them…

Machine Learning · Computer Science 2020-08-06 Hanqing Zeng , Hongkuan Zhou , Ajitesh Srivastava , Rajgopal Kannan , Viktor Prasanna

Time-series single-cell RNA-sequencing (scRNA-seq) datasets offer unprecedented insights into the dynamics and heterogeneity of cellular systems. These systems exhibit multiscale collective behaviors driven by intricate intracellular gene…

Quantitative Methods · Quantitative Biology 2025-05-23 Qi Jiang , Lei Zhang , Longquan Li , Lin Wan

Recognizing multiple labels of images is a practical and challenging task, and significant progress has been made by searching semantic-aware regions and modeling label dependency. However, current methods cannot locate the semantic regions…

Computer Vision and Pattern Recognition · Computer Science 2019-08-21 Tianshui Chen , Muxin Xu , Xiaolu Hui , Hefeng Wu , Liang Lin

Graph clustering, which aims to divide nodes in the graph into several distinct clusters, is a fundamental yet challenging task. Benefiting from the powerful representation capability of deep learning, deep graph clustering methods have…

Machine Learning · Computer Science 2023-09-13 Yue Liu , Jun Xia , Sihang Zhou , Xihong Yang , Ke Liang , Chenchen Fan , Yan Zhuang , Stan Z. Li , Xinwang Liu , Kunlun He

Gene regulatory network (GRN) refers to the complex network formed by regulatory interactions between genes in living cells. In this paper, we consider inferring GRNs in single cells based on single cell RNA sequencing (scRNA-seq) data. In…

Molecular Networks · Quantitative Biology 2022-05-24 Junjie Tang , Changhu Wang , Feiyi Xiao , Ruibin Xi

High-dimensional point cloud data arise across many scientific domains, especially single-cell biology. The shapes or topologies of these datasets determine the types of information that can be extracted. For example, clustered data…

Unsupervised graph representation learning aims to learn low-dimensional node embeddings without supervision while preserving graph topological structures and node attributive features. Previous graph neural networks (GNN) require a large…

Machine Learning · Computer Science 2020-09-04 Yanqiao Zhu , Yichen Xu , Feng Yu , Shu Wu , Liang Wang

We introduce a novel self-supervised deep clustering approach tailored for unstructured data without requiring prior knowledge of the number of clusters, termed Adaptive Self-supervised Robust Clustering (ASRC). In particular, ASRC…

Machine Learning · Computer Science 2024-07-31 Chen-Lu Ding , Jiancan Wu , Wei Lin , Shiyang Shen , Xiang Wang , Yancheng Yuan

Influenced by breakthroughs in LLMs, single-cell foundation models are emerging. While these models show successful performance in cell type clustering, phenotype classification, and gene perturbation response prediction, it remains to be…

Graph-level clustering remains a pivotal yet formidable challenge in graph learning. Recently, the integration of deep learning with representation learning has demonstrated notable advancements, yielding performance enhancements to a…

Graph node classification with few labeled nodes presents significant challenges due to limited supervision. Conventional methods often exploit the graph in a transductive learning manner. They fail to effectively utilize the abundant…

Machine Learning · Computer Science 2024-07-03 Shuaike Xu , Xiaolin Zhang , Peng Zhang , Kun Zhan

Motivation: Identifying interaction clusters of large gene regulatory networks (GRNs) is critical for its further investigation, while this task is very challenging, attributed to data noise in experiment data, large scale of GRNs, and…

Machine Learning · Computer Science 2019-10-22 Yu Chen , Yuanyuan Yang , Yaochu Jin , Xiufen Zou