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Single-cell sequencing technologies reveal cellular heterogeneity at high resolution, advancing our understanding of biological complexity. As datasets start to scale to tens of millions of cells, computational workflows face substantial…

Semantic change detection (SCD) extends the binary change detection task to provide not only the change locations but also the detailed "from-to" categories in multi-temporal remote sensing data. Such detailed semantic insights into changes…

Computer Vision and Pattern Recognition · Computer Science 2025-07-16 Zhengyi Xu , Haoran Wu , Wen Jiang , Jie Geng

Advances in single-cell sequencing have enabled high-resolution profiling of diverse molecular modalities, while integrating unpaired multi-omics single-cell data remains challenging. Existing approaches either rely on pair information or…

Quantitative Methods · Quantitative Biology 2026-01-21 Jianle Sun , Chaoqi Liang , Ran Wei , Peng Zheng , Lei Bai , Wanli Ouyang , Hongliang Yan , Peng Ye

Recent years have witnessed the rapid development of heterogeneous graph neural networks (HGNNs) in information retrieval (IR) applications. Many existing HGNNs design a variety of tailor-made graph convolutions to capture structural and…

Machine Learning · Computer Science 2023-08-15 Chenguang Du , Kaichun Yao , Hengshu Zhu , Deqing Wang , Fuzhen Zhuang , Hui Xiong

Federated clustering addresses the critical challenge of extracting patterns from decentralized, unlabeled data. However, it is hampered by the flaw that current approaches are forced to accept a compromise between performance and privacy:…

Machine Learning · Computer Science 2025-11-17 Guanxiong He , Jie Wang , Liaoyuan Tang , Zheng Wang , Rong Wang , Feiping Nie

Graph convolutional network (GCN) is a powerful model studied broadly in various graph structural data learning tasks. However, to mitigate the over-smoothing phenomenon, and deal with heterogeneous graph structural data, the design of GCN…

Machine Learning · Statistics 2024-12-12 Jia Cai , Zhilong Xiong , Shaogao Lv

Single-cell transcriptomics techniques, such as scRNA-seq, attempt to characterize gene expression profiles in each cell of a heterogeneous sample individually. Due to growing amounts of data generated and the increasing complexity of the…

Genomics · Quantitative Biology 2023-05-02 Laura Puente-Santamaría , Luis del Peso

Self-supervised learning (SSL) has proven to be a powerful approach for extracting biologically meaningful representations from single-cell data. To advance our understanding of SSL methods applied to single-cell data, we present…

Quantitative Methods · Quantitative Biology 2025-06-13 Olga Ovcharenko , Florian Barkmann , Philip Toma , Imant Daunhawer , Julia Vogt , Sebastian Schelter , Valentina Boeva

While there have been many studies on hardware acceleration for deep learning on images, there has been a rather limited focus on accelerating deep learning applications involving graphs. The unique characteristics of graphs, such as the…

Machine Learning · Computer Science 2021-11-12 Atefeh Sohrabizadeh , Yuze Chi , Jason Cong

Despite plentiful successes achieved by graph representation learning in various domains, the training of graph neural networks (GNNs) still remains tenaciously challenging due to the tremendous computational overhead needed for sizable…

Machine Learning · Computer Science 2025-05-28 Yurui Lai , Taiyan Zhang , Renchi Yang

Brain atlases are essential for reducing the dimensionality of neuroimaging data and enabling interpretable analysis. However, most existing atlases are predefined, group-level templates with limited flexibility and resolution. We present…

Neurons and Cognition · Quantitative Biology 2025-09-23 Mo Wang , Kaining Peng , Jingsheng Tang , Hongkai Wen , Quanying Liu

Subspace clustering seeks to identify subspaces that segment a set of n data points into k (k<<n) groups, which has emerged as a powerful tool for analyzing data from various domains, especially images and videos. Recently, several studies…

Social and Information Networks · Computer Science 2024-11-19 Xiaoyang Lin , Renchi Yang , Haoran Zheng , Xiangyu Ke

Spectral clustering is a leading and popular technique in unsupervised data analysis. Two of its major limitations are scalability and generalization of the spectral embedding (i.e., out-of-sample-extension). In this paper we introduce a…

Machine Learning · Statistics 2024-11-06 Uri Shaham , Kelly Stanton , Henry Li , Boaz Nadler , Ronen Basri , Yuval Kluger

For multimodal skeleton-based action recognition, Graph Convolutional Networks (GCNs) are effective models. Still, their reliance on floating-point computations leads to high energy consumption, limiting their applicability in…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Naichuan Zheng , Yuchen Du , Hailun Xia , Zeyu Liang

The exploration of cellular heterogeneity within the tumor microenvironment (TME) via single-cell RNA sequencing (scRNA-seq) is essential for understanding cancer progression and response to therapy. Current scRNA-seq approaches, however,…

Genomics · Quantitative Biology 2025-02-06 Yu-An Huang , Yue-Chao Li , Hai-Ru You , Jie Pan , Xiyue Cao , Xinyuan Li , Zhi-An Huang , Zhu-Hong You

Graph clustering is a fundamental task which discovers communities or groups in networks. Recent studies have mostly focused on developing deep learning approaches to learn a compact graph embedding, upon which classic clustering methods…

Machine Learning · Computer Science 2019-06-18 Chun Wang , Shirui Pan , Ruiqi Hu , Guodong Long , Jing Jiang , Chengqi Zhang

Single-cell RNA sequencing (scRNA-seq) has the potential to provide powerful, high-resolution signatures to inform disease prognosis and precision medicine. This paper takes an important first step towards this goal by developing an…

Quantitative Methods · Quantitative Biology 2021-10-15 Bryan He , Matthew Thomson , Meena Subramaniam , Richard Perez , Chun Jimmie Ye , James Zou

Deep convolutional neural networks (CNNs) achieve remarkable performance on image classification tasks. Recent studies, however, have demonstrated that generalization abilities are more important than the depth of neural networks for…

Computer Vision and Pattern Recognition · Computer Science 2017-10-04 Atsushi Takeda

Deep graph clustering (DGC) for attribute-missing graphs is an unsupervised task aimed at partitioning nodes with incomplete attributes into distinct clusters. Addressing this challenging issue is vital for practical applications. However,…

Machine Learning · Computer Science 2025-08-06 Yaowen Hu , Wenxuan Tu , Yue Liu , Miaomiao Li , Wenpeng Lu , Zhigang Luo , Xinwang Liu , Ping Chen

Recent advancements in single-cell genomics necessitate precision in gene panel selection to interpret complex biological data effectively. Those methods aim to streamline the analysis of scRNA-seq data by focusing on the most informative…

Artificial Intelligence · Computer Science 2024-06-12 Weiliang Zhang , Zhen Meng , Dongjie Wang , Min Wu , Kunpeng Liu , Yuanchun Zhou , Meng Xiao