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Training deep neural networks has become increasingly demanding, requiring large datasets and significant computational resources, especially as model complexity advances. Data distillation methods, which aim to improve data efficiency,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Sunwoo Cho , Yejin Jung , Nam Ik Cho , Jae Woong Soh

Decision Transformer (DT), a trajectory modelling method, has shown competitive performance compared to traditional offline reinforcement learning (RL) approaches on various classic control tasks. However, it struggles to learn optimal…

Machine Learning · Computer Science 2025-09-18 Xingshuai Huang , Di Wu , Benoit Boulet

Single-cell RNA sequencing (scRNA-seq) data exhibit strong and reproducible statistical structure. This has motivated the development of large-scale foundation models, such as TranscriptFormer, that use transformer-based architectures to…

Genomics · Quantitative Biology 2026-02-19 Huan Souza , Pankaj Mehta

The development of novel high-throughput sequencing (HTS) methods for RNA (RNA-Seq) has provided a very powerful mean to study splicing under multiple conditions at unprecedented depth. However, the complexity of the information to be…

Genomics · Quantitative Biology 2015-08-03 Gael P. Alamancos , Eneritz Agirre , Eduardo Eyras

Single-cell RNA sequencing allows the quantification of gene expression at the individual cell level, enabling the study of cellular heterogeneity and gene expression dynamics. Dimensionality reduction is a common preprocessing step…

Computation · Statistics 2025-10-14 Cristian Castiglione , Alexandre Segers , Lieven Clement , Davide Risso

Recent advances in technology have enabled the measurement of RNA levels for individual cells. Compared to traditional tissue-level bulk RNA-seq data, single cell sequencing yields valuable insights about gene expression profiles for…

Applications · Statistics 2019-04-16 Lingxue Zhu , Jing Lei , Bernie Devlin , Kathryn Roeder

scRNA-seq clustering is a critical task for analyzing single-cell RNA sequencing (scRNA-seq) data, as it groups cells with similar gene expression profiles. Transformers, as powerful foundational models, have been applied to scRNA-seq…

Machine Learning · Computer Science 2026-02-10 Zhuomin Liang , Liang Bai , Xian Yang

Single cell combinatorial indexing RNA sequencing (sci-RNA-seq) is a powerful method for recovering gene expression data from an exponentially scalable number of individual cells or nuclei. However, sci-RNA-seq is a complex protocol that…

Although the diffusion model has achieved remarkable performance in the field of image generation, its high inference delay hinders its wide application in edge devices with scarce computing resources. Therefore, many training-free sampling…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Weilun Feng , Chuanguang Yang , Zhulin An , Libo Huang , Boyu Diao , Fei Wang , Yongjun Xu

Data augmentation (DA) can significantly strengthen the electroencephalogram (EEG)-based seizure prediction methods. However, existing DA approaches are just the linear transformations of original data and cannot explore the feature space…

Signal Processing · Electrical Eng. & Systems 2024-12-10 Kai Shu , Le Wu , Yuchang Zhao , Aiping Liu , Ruobing Qian , Xun Chen

Background: Single-cell RNA sequencing (scRNA-seq) is a powerful profiling technique at the single-cell resolution. Appropriate analysis of scRNA-seq data can characterize molecular heterogeneity and shed light into the underlying cellular…

Applications · Statistics 2019-08-05 Siamak Zamani Dadaneh , Paul de Figueiredo , Sing-Hoi Sze , Mingyuan Zhou , Xiaoning Qian

Self-supervised learning has garnered increasing attention in time series analysis for benefiting various downstream tasks and reducing reliance on labeled data. Despite its effectiveness, existing methods often struggle to comprehensively…

Machine Learning · Computer Science 2025-06-12 Daoyu Wang , Mingyue Cheng , Zhiding Liu , Qi Liu

Diffusion models have significantly reshaped the field of generative artificial intelligence and are now increasingly explored for their capacity in discriminative representation learning. Diffusion Transformer (DiT) has recently gained…

Computer Vision and Pattern Recognition · Computer Science 2026-03-30 Changyu Liu , James Chenhao Liang , Wenhao Yang , Yiming Cui , Jinghao Yang , Tianyang Wang , Qifan Wang , Dongfang Liu , Cheng Han

Single-cell RNA sequencing provides insights into gene expression at single-cell resolution, yet inferring temporal processes from these static snapshot measurements remains a fundamental challenge. Current approaches utilizing neural…

Machine Learning · Computer Science 2026-05-21 Mehmet Yigit Balik , Harri Lähdesmäki

Sequential Recommender Systems (SRS) aim to model sequential behaviors of users to capture their interests which usually evolve over time. Transformer-based SRS have achieved distinguished successes recently. However, studies reveal…

Information Retrieval · Computer Science 2025-08-04 Sheng Lu , Mingxi Ge , Jiuyi Zhang , Wanli Zhu , Guanjin Li , Fangming Gu

Currently, high-fidelity text-to-image models are developed in an accelerating pace. Among them, Diffusion Models have led to a remarkable improvement in the quality of image generation, making it vary challenging to distinguish between…

Computer Vision and Pattern Recognition · Computer Science 2024-11-21 Ziyue Zeng , Haoyuan Liu , Dingjie Peng , Luoxu Jing , Hiroshi Watanabe

Diffusion models are pivotal for generating high-quality images and videos. Inspired by the success of OpenAI's Sora, the backbone of diffusion models is evolving from U-Net to Transformer, known as Diffusion Transformers (DiTs). However,…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-11-05 Jiarui Fang , Jinzhe Pan , Xibo Sun , Aoyu Li , Jiannan Wang

High-resolution diffusion tensor imaging (DTI) is beneficial for probing tissue microstructure in fine neuroanatomical structures, but long scan times and limited signal-to-noise ratio pose significant barriers to acquiring DTI at…

Image and Video Processing · Electrical Eng. & Systems 2021-02-19 Qiyuan Tian , Ziyu Li , Qiuyun Fan , Chanon Ngamsombat , Yuxin Hu , Congyu Liao , Fuyixue Wang , Kawin Setsompop , Jonathan R. Polimeni , Berkin Bilgic , Susie Y. Huang

Although recent research applying text-to-image (T2I) diffusion models to real-world super-resolution (SR) has achieved remarkable progress, the misalignment of their targets leads to a suboptimal trade-off between inference speed and…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Yan Wang , Shijie Zhao , Kexin Zhang , Junlin Li , Li Zhang

Diffusion models have achieved remarkable success in generating high-resolution, realistic images across diverse natural distributions. However, their performance heavily relies on high-quality training data, making it challenging to learn…

Machine Learning · Computer Science 2025-05-22 Tianyu Chen , Yasi Zhang , Zhendong Wang , Ying Nian Wu , Oscar Leong , Mingyuan Zhou
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