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We present a general geometrical approach to the problem of escape from a metastable state in the presence of noise. The accompanying analysis leads to a simple condition, based on the norm of the drift field, for determining whether…

Mathematical Physics · Physics 2016-01-20 Daniele Pinna , Andrew D. Kent , Daniel L. Stein

Natural animal behavior displays rich lexical and temporal dynamics, even in a stable environment. This implies that behavioral variability arises from sources within the brain, but the origin and mechanics of these processes remain largely…

Neurons and Cognition · Quantitative Biology 2020-01-28 Stefano Recanatesi , Ulises Pereira , Masayoshi Murakami , Zachary Mainen , Luca Mazzucato

Neural networks encode information through their collective spiking activity in response to external stimuli. This population response is noisy and strongly correlated, with complex interplay between correlations induced by the stimulus,…

Neurons and Cognition · Quantitative Biology 2022-11-28 Gabriel Mahuas , Olivier Marre , Thierry Mora , Ulisse Ferrari

Neuronal ensemble activity, including coordinated and oscillatory patterns, exhibits hallmarks of nonequilibrium systems with time-asymmetric trajectories to maintain their organization. However, assessing time asymmetry from neuronal…

Neurons and Cognition · Quantitative Biology 2025-12-12 Ken Ishihara , Hideaki Shimazaki

A theoretical approach for characterising the influence of asymmetry of noise distribution on the escape rate of a multi-stable system is presented. This was carried out via the estimation of an action, which is defined as an exponential…

Mesoscale and Nanoscale Physics · Physics 2014-02-26 I. A. Khovanov , N. A. Khovanova

We consider the dynamics of a periodic chain of N coupled overdamped particles under the influence of noise. Each particle is subjected to a bistable local potential, to a linear coupling with its nearest neighbours, and to an independent…

Probability · Mathematics 2007-10-16 Nils Berglund , Bastien Fernandez , Barbara Gentz

Rare transitions between long-lived metastable states underlie a great variety of physical, chemical and biological processes. Our quantitative understanding of reactive mechanisms has been driven forward by the insights of transition state…

We study the learning of an external signal by a neural network and the time to forget it when this network is submitted to noise. The presentation of an external stimulus to the recurrent network of binary neurons may change the state of…

Probability · Mathematics 2020-06-11 Pascal Helson

Correlations are employed in modern physics to explain microscopic and macroscopic phenomena, like the fractional quantum Hall effect and the Mott insulator state in high temperature superconductors and ultracold atoms. Simultaneously…

Neurons and Cognition · Quantitative Biology 2013-02-20 Moritz Helias , Tom Tetzlaff , Markus Diesmann

A perturbation framework is developed to analyze metastable behavior in stochastic processes with random internal and external states. The process is assumed to be under weak noise conditions, and the case where the deterministic limit is…

Analysis of PDEs · Mathematics 2013-09-23 Jay Newby , Jon Chapman

We investigate the efficient transmission and processing of weak, subthreshold signals in a realistic neural medium in the presence of different levels of the underlying noise. Assuming Hebbian weights for maximal synaptic conductances --…

Biological Physics · Physics 2015-08-19 Joaquin J. Torres , Irene Elices , J. Marro

Neurons in many brain areas can develop pronounced depolarized state of membrane potential (up state) in addition to the normal hyperpolarized down state near the resting potential. The influence of the up state on signal encoding, however,…

Neurons and Cognition · Quantitative Biology 2015-09-30 Wei Wei , Fred Wolf , Xiao-Jing Wang

We explore the archetype problem of an escape dynamics occurring in a symmetric double well potential when the Brownian particle is driven by {\it white L\'evy noise} in a dynamical regime where inertial effects can safely be neglected. The…

Statistical Mechanics · Physics 2009-11-11 B. Dybiec E. Gudowska-Nowak P. Hänggi

We demonstrate that the information contained in the spike occurrence times of a population of neurons can be broken up into a series of terms, each of which reflect something about potential coding mechanisms. This is possible in the…

Biological Physics · Physics 2007-05-23 S. Panzeri , S. R. Schultz

Interspike intervals describe the output of neurons. Signal transmission in a neuronal network implies that the output of some neurons becomes the input of others. The output should reproduce the main features of the input to avoid a…

Probability · Mathematics 2022-09-29 Petr Lansky , Federico Polito , Laura Sacerdote

Complex networks, from neuronal assemblies to social systems, can exhibit abrupt, system-wide transitions without external forcing. These endogenously generated ``noise-induced transitions'' emerge from the intricate interplay between…

Social and Information Networks · Computer Science 2024-09-04 Casper van Elteren , Rick Quax , Peter Sloot

Synaptic connections in neuronal circuits are modulated by pre- and post-synaptic spiking activity. Heuristic models of this process of synaptic plasticity can provide excellent fits to results from in-vitro experiments in which pre- and…

Neurons and Cognition · Quantitative Biology 2022-07-14 Federico Devalle , Alex Roxin

The paper addresses the problem of calculating the noise-induced switching rates in systems with delay-distributed kernels and Gaussian noise. A general variational formulation for the switching rate is derived for any distribution kernel,…

Data Analysis, Statistics and Probability · Physics 2018-07-04 Y. N. Kyrychko , I. B. Schwartz

Neural dynamics is determined by the transmission of discrete synaptic pulses (synaptic shot-noise) among neurons. However, the neural responses are usually obtained within the diffusion approximation modeling synaptic inputs as continuous…

Disordered Systems and Neural Networks · Physics 2025-10-17 Denis S. Goldobin , Maria V. Ageeva , Matteo di Volo , Ferdinand Tixidre , Alessandro Torcini

In a manner similar to the molecular chaos that underlies the stable thermodynamics of gases, neuronal system may exhibit microscopic instability in individual neuronal dynamics while a macroscopic order of the entire population possibly…

Neurons and Cognition · Quantitative Biology 2015-06-23 Yuzuru Yamanaka , Shun-ichi Amari , Shigeru Shinomoto