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Transitions between multiple stable states of nonlinear systems are ubiquitous in physics, chemistry, and beyond. Two types of behaviors are usually seen as mutually exclusive: unpredictable noise-induced transitions and predictable…

Statistical Mechanics · Physics 2017-10-03 Corentin Herbert , Freddy Bouchet

Cortical activity in-vivo displays relaxational time scales much longer than the membrane time constant of the neurons or the deactivation time of ionotropic synaptic conductances. The mechanisms responsible for such slow dynamics are not…

Disordered Systems and Neural Networks · Physics 2025-08-07 Ferdinand Tixidre , Gianluigi Mongillo , Alessandro Torcini

Using an exactly solvable cortical model of a neuronal network, we show that, by increasing the intensity of shot noise (flow of random spikes bombarding neurons), the network undergoes first- and second-order non-equilibrium phase…

Biological Physics · Physics 2015-08-26 K. -E. Lee , M. A. Lopes , A. V. Goltsev

Given a population of interconnected input-output agents repeatedly exposed to independent random inputs, we talk of correlated variability when agents' outputs are variable (i.e., they change randomly at each input repetition) but…

Quantitative Methods · Quantitative Biology 2021-10-15 Marcela Ordorica Arango , Alessio Franci

Many systems are modulated by unknown slow processes. This hinders analysis in highly non-linear systems, such as excitable systems. We show that for such systems, if the input matches the sparse `spiky' nature of the output, the spiking…

Neurons and Cognition · Quantitative Biology 2014-05-01 Daniel Soudry , Ron Meir

It is well known that the addition of noise to a multistable dynamical system can induce random transitions from one stable state to another. For low noise, the times between transitions have an exponential tail and Kramers' formula gives…

Dynamical Systems · Mathematics 2017-11-15 Peter Ashwin , Jennifer Creaser , Krasimira Tsaneva-Atanasova

We study temporal correlations of interspike intervals (ISIs), quantified by the network-averaged serial correlation coefficient (SCC), in networks of both current- and conductance-based purely inhibitory integrate-and-fire neurons.…

Neurons and Cognition · Quantitative Biology 2019-03-27 Wilhelm Braun , André Longtin

We assess the impact of cell cycle noise on gene circuit dynamics. For bistable genetic switches and excitable circuits, we find that transitions between metastable states most likely occur just after cell division and that this…

Molecular Networks · Quantitative Biology 2016-12-21 Alan Veliz-Cuba , Chinmaya Gupta , Matthew R. Bennett , Krešimir Josić , William Ott

We consider a stochastic version of an excitable system based on the Morris-Lecar model of a neuron, in which the noise originates from stochastic Sodium and Potassium ion channels opening and closing. One can analyze neural excitability in…

Neurons and Cognition · Quantitative Biology 2015-06-15 Jay M. Newby , Paul C. Bressloff , James P. Keener

Noise, through its interaction with the nonlinearity of the living systems, can give rise to counter-intuitive phenomena such as stochastic resonance, noise-delayed extinction, temporal oscillations, and spatial patterns. In this paper we…

Populations and Evolution · Quantitative Biology 2007-05-23 B. Spagnolo , D. Valenti , A. Fiasconaro

The highly variable dynamics of neocortical circuits observed in vivo have been hypothesized to represent a signature of ongoing stochastic inference but stand in apparent contrast to the deterministic response of neurons measured in vitro.…

Neurons and Cognition · Quantitative Biology 2017-03-14 Mihai A. Petrovici , Johannes Bill , Ilja Bytschok , Johannes Schemmel , Karlheinz Meier

A goal of data assimilation is to infer stochastic dynamical behaviors with available observations. We consider transition phenomena between metastable states for a stochastic system with (non-Gaussian) $\alpha-$stable L\'evy noise. With…

Dynamical Systems · Mathematics 2016-06-29 Ting Gao , Jinqiao Duan , Xingye Kan

This paper considers the state transition of the stochastic Morris-Lecar neuronal model driven by symmetric $\alpha$-stable L\'evy noise. The considered system is bistable: a stable fixed point (resting state) and a stable limit cycle…

Dynamical Systems · Mathematics 2019-06-19 Rui Cai , Yancai Liu , Jinqiao Duan , Almaz Tesfay Abebe

We introduce an extension to the standard reduction of oscillatory systems to a single phase variable. The standard reduction is often insufficient, particularly when the oscillations have variable amplitude and the magnitude of each…

Neurons and Cognition · Quantitative Biology 2024-11-12 Avinash J. Karamchandani

We continue the work of a series of previous studies of a mathematical model that describes the mean-field limit behavior of a homogeneous network of excitatory point spiking neurons. Contrary to other models, here noise is intrinsic to the…

Neurons and Cognition · Quantitative Biology 2017-07-20 Guillem Via

We consider effect of stochastic sources upon self-organization process being initiated with creation of the limit cycle. General expressions obtained are applied to the stochastic Lorenz system to show that departure from equilibrium…

Statistical Mechanics · Physics 2015-05-13 I. A. Shuda , S. S. Borysov , A. I. Olemskoi

Neurons in the brain continuously process the barrage of sensory inputs they receive from the environment. A wide array of experimental work has shown that the collective activity of neural populations encodes and processes this constant…

Neurons and Cognition · Quantitative Biology 2025-10-30 Siddharth Paliwal , Gabriel Koch Ocker , Braden A. W. Brinkman

A classical view of neural coding relies on temporal firing synchrony among functional groups of neurons; however the underlying mechanism remains an enigma. Here we experimentally demonstrate a mechanism where time-lags among neuronal…

Neurons and Cognition · Quantitative Biology 2013-10-31 Roni Vardi , Amir Goldental , Shoshana Guberman , Alexander Kalmanovich , Hagar Marmari , Ido Kanter

Autonomous randomly coupled neural networks display a transition to chaos at a critical coupling strength. We here investigate the effect of a time-varying input on the onset of chaos and the resulting consequences for information…

Neurons and Cognition · Quantitative Biology 2018-11-21 Jannis Schuecker , Sven Goedeke , Moritz Helias

We investigate the role of noise in the phenomenon of stochastic synchronization of switching events in a rocked, overdamped bistable potential driven by white Gaussian noise, the archetype description of Stochastic Resonance. We present a…

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