English
Related papers

Related papers: Clinical Trials Protocol Authoring using LLMs

200 papers

Large language models (LLMs) have demonstrated significant potential to accelerate scientific discovery as valuable tools for analyzing data, generating hypotheses, and supporting innovative approaches in various scientific fields. In this…

Computation and Language · Computer Science 2025-10-30 Jin Huang , Silviu Cucerzan , Sujay Kumar Jauhar , Ryen W. White

Process mining has emerged as a powerful analytical technique for understanding complex healthcare workflows. However, its application faces significant barriers, including technical complexity, a lack of standardized approaches, and…

Artificial Intelligence · Computer Science 2026-02-11 Eduardo Illueca-Fernandez , Kaile Chen , Fernando Seoane , Farhad Abtahi

The rapid expansion of electronic health record (EHR) systems has generated large volumes of unstructured clinical narratives that contain valuable information for disease identification, patient cohort discovery, and clinical decision…

Computation and Language · Computer Science 2026-03-17 Fariba Afrin Irany , Sampson Akwafuo

The introduction of genome engineering technology has transformed biomedical research, making it possible to make precise changes to genetic information. However, creating an efficient gene-editing system requires a deep understanding of…

Access to high-quality medical data is often restricted due to privacy concerns, posing significant challenges for training artificial intelligence (AI) algorithms within Electronic Health Record (EHR) applications. In this study, prompt…

Artificial Intelligence · Computer Science 2025-04-30 Polycarp Nalela

The recent release of very large language models such as PaLM and GPT-4 has made an unprecedented impact in the popular media and public consciousness, giving rise to a mixture of excitement and fear as to their capabilities and potential…

Large Language Models (LLMs) have revolutionized AI systems by enabling communication with machines using natural language. Recent developments in Generative AI (GenAI) like Vision-Language Models (GPT-4V) and Gemini have shown great…

Computation and Language · Computer Science 2024-07-17 Jakub M. Tomczak

As researchers increasingly adopt LLMs as writing assistants, generating high-quality research paper introductions remains both challenging and essential. We introduce Scientific Introduction Generation (SciIG), a task that evaluates LLMs'…

Computation and Language · Computer Science 2025-08-26 Krishna Garg , Firoz Shaik , Sambaran Bandyopadhyay , Cornelia Caragea

Introduction: Recently, the effectiveness of Large Language Models (LLMs) has increased rapidly, allowing them to be used in a great number of applications. However, the risks posed by the generation of false information through LLMs…

Computation and Language · Computer Science 2024-05-10 Jakub Pokrywka , Jeremi Kaczmarek , Edward Gorzelańczyk

Engineering safety-critical systems such as medical devices and digital health intervention systems is complex, where long-term engagement with subject-matter experts (SMEs) is needed to capture the systems' expected behaviour. In this…

Synthesizing clinical evidence largely relies on systematic reviews of clinical trials and retrospective analyses from medical literature. However, the rapid expansion of publications presents challenges in efficiently identifying,…

Computation and Language · Computer Science 2024-10-30 Zifeng Wang , Lang Cao , Benjamin Danek , Qiao Jin , Zhiyong Lu , Jimeng Sun

This document offers a critical overview of the emerging trends and significant advancements in artificial intelligence (AI) within the pharmaceutical industry. Detailing its application across key operational areas, including research and…

Computers and Society · Computer Science 2024-01-23 Yu Han , Jingwen Tao

The growing availability of generative AI technologies such as large language models (LLMs) has significant implications for creative work. This paper explores twofold aspects of integrating LLMs into the creative process - the divergence…

Human-Computer Interaction · Computer Science 2024-03-04 Orit Shaer , Angelora Cooper , Osnat Mokryn , Andrew L. Kun , Hagit Ben Shoshan

The growing capabilities of Artificial Intelligence (AI), particularly Large Language Models (LLMs), prompt a reassessment of the interaction mechanisms between users and their devices. Currently, users are required to use a set of…

Artificial Intelligence · Computer Science 2025-10-10 Justus Flerlage , Ilja Behnke , Odej Kao

Recent investigations show that large language models (LLMs), specifically GPT-4, not only have remarkable capabilities in common Natural Language Processing (NLP) tasks but also exhibit human-level performance on various professional and…

Computation and Language · Computer Science 2023-06-05 Zhuo Wang , Rongzhen Li , Bowen Dong , Jie Wang , Xiuxing Li , Ning Liu , Chenhui Mao , Wei Zhang , Liling Dong , Jing Gao , Jianyong Wang

This paper takes an exploratory approach to examine the use of ChatGPT for pattern mining. It proposes an eight-step collaborative process that combines human insight with AI capabilities to extract patterns from known uses. The paper…

Artificial Intelligence · Computer Science 2024-12-24 Michael Weiss

Cognitive psychology delves on understanding perception, attention, memory, language, problem-solving, decision-making, and reasoning. Large language models (LLMs) are emerging as potent tools increasingly capable of performing human-level…

Computation and Language · Computer Science 2023-04-13 Sifatkaur Dhingra , Manmeet Singh , Vaisakh SB , Neetiraj Malviya , Sukhpal Singh Gill

Generative Artificial Intelligence (AI) is revolutionizing educational technology by enabling highly personalized and adaptive learning environments within Intelligent Tutoring Systems (ITS). This report delves into the integration of…

Computation and Language · Computer Science 2024-10-15 Subhankar Maity , Aniket Deroy

Artificial intelligence (AI) has transformed medical imaging, with computer vision (CV) systems achieving state-of-the-art performance in classification and detection tasks. However, these systems typically output structured predictions,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Trishna Niraula , Jonathan Stubblefield

We study compiled AI, a paradigm in which large language models generate executable code artifacts during a compilation phase, after which workflows execute deterministically without further model invocation. This paradigm has antecedents…