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Accurate classification of focal liver lesions is crucial for diagnosis and treatment in hepatology. However, traditional supervised deep learning models depend on large-scale annotated datasets, which are often limited in medical imaging.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-07 Song Jian , Hu Yuchang , Wang Hui , Chen Yen-Wei

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and the fourth most common cause of cancer-related death worldwide. Understanding the underlying gene mutations in HCC provides great prognostic value for…

Automatic segmentation of liver lesions is a fundamental requirement towards the creation of computer aided diagnosis (CAD) and decision support systems (CDS). Traditional segmentation approaches depend heavily upon hand-crafted features…

Computer Vision and Pattern Recognition · Computer Science 2017-05-23 Lei Bi , Jinman Kim , Ashnil Kumar , Dagan Feng

Clinical cystoscopy, the current standard for bladder cancer diagnosis, suffers from significant reliance on physician expertise, leading to variability and subjectivity in diagnostic outcomes. There is an urgent need for objective,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Jinliang Yu , Mingduo Xie , Yue Wang , Tianfan Fu , Xianglai Xu , Jiajun Wang

Early detection of lung cancer is critical for improvement of patient survival. To address the clinical need for efficacious treatments, genetically engineered mouse models (GEMM) have become integral in identifying and evaluating the…

Pediatric liver tumors are one of the most common solid tumors in pediatrics, with differentiation of benign or malignant status and pathological classification critical for clinical treatment. While pathological examination is the gold…

Image and Video Processing · Electrical Eng. & Systems 2026-01-29 Wanqi Wang , Chun Yang , Jianbo Shao , Yaokai Zhang , Xuehua Peng , Jin Sun , Chao Xiong , Long Lu , Lianting Hu

Patch classification models based on deep learning have been utilized in whole-slide images (WSI) of H&E-stained tissue samples to assist pathologists in grading follicular lymphoma patients. However, these approaches still require…

Prostate cancer (PCa) is graded by pathologists by examining the architectural pattern of cancerous epithelial tissue on hematoxylin and eosin (H&E) stained slides. Given the importance of gland morphology, automatically differentiating…

Efficient and precise classification of histological cell nuclei is of utmost importance due to its potential applications in the field of medical image analysis. It would facilitate the medical practitioners to better understand and…

Computer Vision and Pattern Recognition · Computer Science 2019-11-19 S H Shabbeer Basha , Soumen Ghosh , Kancharagunta Kishan Babu , Shiv Ram Dubey , Viswanath Pulabaigari , Snehasis Mukherjee

We propose an unsupervised method using self-clustering convolutional adversarial autoencoders to classify prostate tissue as tumor or non-tumor without any labeled training data. The clustering method is integrated into the training of the…

Computer Vision and Pattern Recognition · Computer Science 2018-04-20 Wouter Bulten , Geert Litjens

Classifying breast cancer molecular subtypes is crucial for tailoring treatment strategies. While immunohistochemistry (IHC) and gene expression profiling are standard methods for molecular subtyping, IHC can be subjective, and gene…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Masoud Tafavvoghi , Anders Sildnes , Mehrdad Rakaee , Nikita Shvetsov , Lars Ailo Bongo , Lill-Tove Rasmussen Busund , Kajsa Møllersen

Primary liver malignancies are widely recognized as the most heterogeneous and prognostically diverse cancers of the digestive system. Among these, hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) emerge as the two…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Anwen Lu , Mingxin Liu , Yiping Jiao , Hongyi Gong , Geyang Xu , Jun Chen , Jun Xu

Molecular subtypes of breast cancer are important references to personalized clinical treatment. For cost and labor savings, only one of the patient's paraffin blocks is usually selected for subsequent immunohistochemistry (IHC) to obtain…

Image and Video Processing · Electrical Eng. & Systems 2022-03-16 Hong Liu , Wen-Dong Xu , Zi-Hao Shang , Xiang-Dong Wang , Hai-Yan Zhou , Ke-Wen Ma , Huan Zhou , Jia-Lin Qi , Jia-Rui Jiang , Li-Lan Tan , Hui-Min Zeng , Hui-Juan Cai , Kuan-Song Wang , Yue-Liang Qian

Diagnosing basal cell carcinomas (BCC), one of the most common cutaneous malignancies in humans, is a task regularly performed by pathologists and dermato-pathologists. Improving histological diagnosis by providing diagnosis suggestions,…

Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and is a leading cause of cancer-related death worldwide. However, cure is not possible with currently used therapies, and there is not so much approved targeted…

Genomics · Quantitative Biology 2017-07-18 Liang Yu , Fengdan Xu , Lin Gao

Liver diseases are a serious health concern in the world, which requires precise and timely diagnosis to enhance the survival chances of patients. The current literature implemented numerous machine learning and deep learning models to…

Screening is critical for prevention and early detection of cervical cancer but it is time-consuming and laborious. Supervised deep convolutional neural networks have been developed to automate pap smear screening and the results are…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 Yu Ando , Nora Jee-Young Park and , Gun Oh Chong , Seokhwan Ko , Donghyeon Lee , Junghwan Cho , Hyungsoo Han

Automated classification of histopathological whole-slide images (WSI) of breast tissue requires analysis at very high resolutions with a large contextual area. In this paper, we present context-aware stacked convolutional neural networks…

Computer Vision and Pattern Recognition · Computer Science 2017-05-11 Babak Ehteshami Bejnordi , Guido Zuidhof , Maschenka Balkenhol , Meyke Hermsen , Peter Bult , Bram van Ginneken , Nico Karssemeijer , Geert Litjens , Jeroen van der Laak

Breast cancer is the most diagnosed cancer and the most predominant cause of death in women worldwide. Imaging techniques such as the breast cancer pathology helps in the diagnosis and monitoring of the disease. However identification of…

Image and Video Processing · Electrical Eng. & Systems 2019-08-06 Francisco Perdigon Romero , An Tang , Samuel Kadoury

Large amounts of unlabelled data are commonplace for many applications in computational pathology, whereas labelled data is often expensive, both in time and cost, to acquire. We investigate the performance of unsupervised and supervised…

Computer Vision and Pattern Recognition · Computer Science 2019-07-27 Koen Dercksen , Wouter Bulten , Geert Litjens