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Hypertension is a potentially unsafe health ailment, which can be indicated directly from the Blood pressure (BP). Hypertension always leads to other health complications. Continuous monitoring of BP is very important; however, cuff-based…

Cardiac Magnetic Resonance (CMR) imaging serves as the gold-standard for evaluating cardiac morphology and function. Typically, a multi-view CMR stack, covering short-axis (SA) and 2/3/4-chamber long-axis (LA) views, is acquired for a…

Image and Video Processing · Electrical Eng. & Systems 2025-07-03 Yundi Zhang , Chen Chen , Suprosanna Shit , Sophie Starck , Daniel Rueckert , Jiazhen Pan

Hypertension and atrial fibrillation (AF) often coexist in critically ill patients, significantly increasing mortality rates in the ICU. Early identification of high-risk individuals is crucial for targeted interventions. However, limited…

Applications · Statistics 2025-06-19 Shuheng Chen , Yong Si , Junyi Fan , Li Sun , Greg Placencia , Elham Pishgar , Kamiar Alaei , Maryam Pishgar

Cardiopulmonary exercise testing (CPET) provides a comprehensive assessment of functional capacity by measuring key physiological variables including oxygen consumption ($VO_2$), carbon dioxide production ($VCO_2$), and pulmonary…

Machine Learning · Computer Science 2025-03-19 Muhammet Alkan , Gruschen Veldtman , Fani Deligianni

Recent developments in cardiovascular modelling allow us to simulate blood flow in an entire human body. Such model can also be used to create databases of virtual subjects, with sizes limited only by computational resources. In this work,…

Medical Physics · Physics 2020-07-01 Janne M. J. Huttunen , Leo Kärkkäinen , Harri Lindholm

Wolff-Parkinson-White (WPW) syndrome is a cardiac electrophysiology (EP) disorder caused by the presence of an accessory pathway (AP) that bypasses the atrioventricular node, faster ventricular activation rate, and provides a substrate for…

Machine Learning · Computer Science 2025-11-11 Alice Ragonesi , Stefania Fresca , Karli Gillette , Stefan Kurath-Koller , Gernot Plank , Elena Zappon

Peripheral Arterial Disease (PAD) is a common form of arterial occlusive disease that is challenging to evaluate at the point-of-care. Hand-held dopplers are the most ubiquitous device used to evaluate circulation and allows providers to…

Sound · Computer Science 2021-06-17 Adrit Rao , Kevin Battenfield , Oliver Aalami

Cardiovascular diseases (CVDs) remain a leading cause of death globally, necessitating continuous, accurate non-invasive cardiac monitoring. While non-contact radar-based approaches show great promise, they often employ a single…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Jinye Li , Aidong Men , Yang Liu , Qingchao Chen

Background: Computational fluid dynamics (CFD) is increasingly used to assess blood flow conditions in patients with congenital heart disease (CHD). This requires patient-specific anatomy, usually obtained from segmented 3D cardiovascular…

Many clinical deep learning algorithms are population-based and difficult to interpret. Such properties limit their clinical utility as population-based findings may not generalize to individual patients and physicians are reluctant to…

Signal Processing · Electrical Eng. & Systems 2020-12-01 Dani Kiyasseh , Tingting Zhu , David A. Clifton

Mathematical models are essential tools to study how the cardiovascular system maintains homeostasis. The utility of such models is limited by the accuracy of their predictions, which can be determined by uncertainty quantification (UQ). A…

Quantitative Methods · Quantitative Biology 2018-07-20 Andrew D. Marquis , Andrea Arnold , Caron Dean , Brian E. Carlson , Mette S. Olufsen

Mathematical modeling of cardiac function can provide augmented simulation-based diagnosis tool for complementing and extending human understanding of cardiac diseases which represent the most common cause of worldwide death. As the…

Computational Engineering, Finance, and Science · Computer Science 2021-05-05 Chi Zhang , Jianhang Wang , Massoud Rezavand , Dong Wu , Xiangyu Hu

Structure-based drug design (SBDD), aiming to generate 3D molecules with high binding affinity toward target proteins, is a vital approach in novel drug discovery. Although recent generative models have shown great potential, they suffer…

Machine Learning · Computer Science 2025-11-05 Jingyuan Zhou , Hao Qian , Shikui Tu , Lei Xu

In the field of multimodal medical data analysis, leveraging diverse types of data and understanding their hidden relationships continues to be a research focus. The main challenges lie in effectively modeling the complex interactions…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Xuhao Shan , Ruiquan Ge , Jikui Liu , Linglong Wu , Chi Zhang , Siqi Liu , Wenjian Qin , Wenwen Min , Ahmed Elazab , Changmiao Wang

We present a pipeline for unbiased and robust multimodal registration of neuroimaging modalities with minimal pre-processing. While typical multimodal studies need to use multiple independent processing pipelines, with diverse options and…

Computer Vision and Pattern Recognition · Computer Science 2024-01-26 Adria Casamitjana , Juan Eugenio Iglesias , Raul Tudela , Aida Ninerola-Baizan , Roser Sala-Llonch

Continuously measured arterial blood velocity can provide insight into physiological parameters and potential disease states. The efficient and effective description of the temporal profiles of arterial velocity is crucial for both clinical…

Quantitative Methods · Quantitative Biology 2024-02-16 Justen R Geddes , Amanda Randles

The Hawkes process (HP) is commonly used to model event sequences with self-reinforcing dynamics, including electronic health records (EHRs). Traditional HPs capture self-reinforcement via parametric impact functions that can be inspected…

Machine Learning · Statistics 2025-10-23 Yuankang Zhao , Matthew Engelhard

Accurate phase estimation at the edge of data segments is crucial for EEG applications such as EEG-TMS in offline and real-time data analysis. Our research evaluates the phase estimation performance of four commonly used methods…

Neurons and Cognition · Quantitative Biology 2026-04-03 Miriam Kirchhoff , Johanna Rösch , Maria Ermolova , Oskari Ahola , Sarah Harders , Juliana Hougland , Ulf Ziemann

This paper proposes a multimodal emotion recognition system based on hybrid fusion that classifies the emotions depicted by speech utterances and corresponding images into discrete classes. A new interpretability technique has been…

Computer Vision and Pattern Recognition · Computer Science 2023-01-10 Puneet Kumar , Sarthak Malik , Balasubramanian Raman

Recent advances in attention-based multiple instance learning (MIL) have improved our insights into the tissue regions that models rely on to make predictions in digital pathology. However, the interpretability of these approaches is still…

Quantitative Methods · Quantitative Biology 2023-09-11 Willem Bonnaffé , CRUK ICGC Prostate Group , Freddie Hamdy , Yang Hu , Ian Mills , Jens Rittscher , Clare Verrill , Dan J. Woodcock