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This article presents Holistically-Attracted Wireframe Parsing (HAWP), a method for geometric analysis of 2D images containing wireframes formed by line segments and junctions. HAWP utilizes a parsimonious Holistic Attraction (HAT) field…

Computer Vision and Pattern Recognition · Computer Science 2023-09-07 Nan Xue , Tianfu Wu , Song Bai , Fu-Dong Wang , Gui-Song Xia , Liangpei Zhang , Philip H. S. Torr

Integrating heterogeneous biomedical data including imaging, omics, and clinical records supports accurate diagnosis and personalised care. Graph-based models fuse such non-Euclidean data by capturing spatial and relational structure, yet…

Genomics · Quantitative Biology 2025-05-06 Alireza Sadeghi , Farshid Hajati , Ahmadreza Argha , Nigel H Lovell , Min Yang , Hamid Alinejad-Rokny

Blood Pressure (BP) is one of the four primary vital signs indicating the status of the body's vital (life-sustaining) functions. BP is difficult to continuously monitor using a sphygmomanometer (i.e. a blood pressure cuff), especially in…

Machine Learning · Computer Science 2021-08-03 Ali Tazarv , Marco Levorato

Coronary heart disease (CHD) is a leading cause of death worldwide and contributes significantly to annual healthcare expenditures. To develop a non-invasive diagnostic approach, we designed a model based on a multilayer perceptron (MLP)…

Machine Learning · Computer Science 2025-09-05 Jesus Celis-Porras

Machine-learning models have demonstrated a great ability to learn complex patterns and make predictions. In high-dimensional nonlinear problems of fluid dynamics, data representation often greatly affects the performance and…

Fluid Dynamics · Physics 2022-07-29 Runze Li , Yufei Zhang , Haixin Chen

Thrombosis in rotary blood pumps arises from complex flow conditions that remain difficult to translate into reliable and interpretable risk predictions using existing computational models. This limitation reflects an incomplete…

Machine Learning · Computer Science 2025-12-19 Christopher Blum , Michael Neidlin

Early and accurate diagnosis of pulmonary hypertension (PH) is essential for optimal patient management. Differentiating between pre-capillary and post-capillary PH is critical for guiding treatment decisions. This study develops and…

Image and Video Processing · Electrical Eng. & Systems 2025-04-03 Fubao Zhu , Yang Zhang , Gengmin Liang , Jiaofen Nan , Yanting Li , Chuang Han , Danyang Sun , Zhiguo Wang , Chen Zhao , Wenxuan Zhou , Jian He , Yi Xu , Iokfai Cheang , Xu Zhu , Yanli Zhou , Weihua Zhou

Survival analysis, or time-to-event analysis, is an important and widespread problem in healthcare research. Medical research has traditionally relied on Cox models for survival analysis, due to their simplicity and interpretability. Cox…

Machine Learning · Computer Science 2023-10-25 Mike Van Ness , Tomas Bosschieter , Natasha Din , Andrew Ambrosy , Alexander Sandhu , Madeleine Udell

The increasing reliance on Computed Tomography Pulmonary Angiography (CTPA) for Pulmonary Embolism (PE) diagnosis presents challenges and a pressing need for improved diagnostic solutions. The primary objective of this study is to leverage…

International initiatives such as METABRIC (Molecular Taxonomy of Breast Cancer International Consortium) have collected several multigenomic and clinical data sets to identify the undergoing molecular processes taking place throughout the…

Machine Learning · Computer Science 2022-11-29 Teodora Reu

Automated cardiac image interpretation has the potential to transform clinical practice in multiple ways including enabling low-cost serial assessment of cardiac function in the primary care and rural setting. We hypothesized that advances…

Local hemodynamic forces play an important role in determining the functional significance of coronary arterial stenosis and understanding the mechanism of coronary disease progression. Computational fluid dynamics (CFD) have been widely…

Computer Vision and Pattern Recognition · Computer Science 2023-05-31 Ziyu Ni , Linda Wei , Lijian Xu , Simon Yu , Qing Xia , Hongsheng Li , Shaoting Zhang

Cardiovascular waveforms contain information for clinical diagnosis. By "learning" and organizing the subtle change of waveform morphology from large amounts of raw waveform data, unsupervised manifold learning helps delineate a…

Quantitative Methods · Quantitative Biology 2019-12-03 Shen-Chih Wang , Hau-Tieng Wu , Po-Hsun Huang , Cheng-Hsi Chang , Chien-Kun Ting , Yu-Ting Lin

Pulmonary Embolism (PE) is a life-threatening disorder associated with high mortality and morbidity. Prompt diagnosis and immediate initiation of therapeutic action is important. We explored a deep learning model to detect PE on volumetric…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Luyao Shi , Deepta Rajan , Shafiq Abedin , Manikanta Srikar Yellapragada , David Beymer , Ehsan Dehghan

Objective: The Mapper algorithm is a qualitative method in topological data analysis that constructs graphs from point clouds by combining dimensionality reduction and clustering techniques. The aim of this study is to apply Mapper,…

Quantitative Methods · Quantitative Biology 2026-04-22 Aina Ferrà Marcús , Carles Casacuberta , Josep Vives , Joan Guich , Gerard Amorós-Figueras , Jose M. Guerra

Accurate and generalizable blood pressure (BP) estimation is vital for the early detection and management of cardiovascular diseases. In this study, we enforce subject-level data splitting on a public multi-wavelength photoplethysmography…

Signal Processing · Electrical Eng. & Systems 2026-01-12 Zequan Liang , Ruoyu Zhang , Wei Shao , Mahdi Pirayesh Shirazi Nejad , Ehsan Kourkchi , Setareh Rafatirad , Houman Homayoun

An accurate assessment of the cardiovascular system and prediction of cardiovascular diseases (CVDs) are crucial. Measured cardiac blood flow data provide insights about patient-specific hemodynamics, where many specialized techniques have…

Medical AI systems face catastrophic forgetting when deployed in clinical settings, where models must learn new imaging protocols while retaining prior diagnostic capabilities. This challenge is particularly acute for medical…

Multimedia · Computer Science 2025-12-23 Ziyuan Gao , Philippe Morel

The current catalyst discovery and development pipeline for energy-intensive applications like methane conversion remains bottlenecked by expensive trial-and-error experimentation, irreproducible chemical intuition, and a lack of frameworks…

Chemical Physics · Physics 2026-05-12 Oyinkansola Romiluyi

Hemodynamic parameters such as pressure and wall shear stress play an important role in diagnosis, prognosis, and treatment planning in cardiovascular diseases. These parameters can be accurately computed using computational fluid dynamics…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Patryk Rygiel , Julian Suk , Kak Khee Yeung , Christoph Brune , Jelmer M. Wolterink