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Large Language Models (LLMs) have revolutionized various sectors, including healthcare where they are employed in diverse applications. Their utility is particularly significant in the context of rare diseases, where data scarcity,…

Computation and Language · Computer Science 2024-08-20 Qiuhao Lu , Rui Li , Andrew Wen , Jinlian Wang , Liwei Wang , Hongfang Liu

With the growing amount of text in health data, there have been rapid advances in large pre-trained models that can be applied to a wide variety of biomedical tasks with minimal task-specific modifications. Emphasizing the cost of these…

In recent years, with the growing amount of biomedical documents, coupled with advancement in natural language processing algorithms, the research on biomedical named entity recognition (BioNER) has increased exponentially. However, BioNER…

Computation and Language · Computer Science 2020-09-22 Usman Naseem , Matloob Khushi , Vinay Reddy , Sakthivel Rajendran , Imran Razzak , Jinman Kim

Recognizing entities in texts is a central need in many information-seeking scenarios, and indeed, Named Entity Recognition (NER) is arguably one of the most successful examples of a widely adopted NLP task and corresponding NLP technology.…

Computation and Language · Computer Science 2023-10-24 Uri Katz , Matan Vetzler , Amir DN Cohen , Yoav Goldberg

The advancement of Large Language Models (LLMs) has significantly impacted biomedical Natural Language Processing (NLP), enhancing tasks such as named entity recognition, relation extraction, event extraction, and text classification. In…

Computation and Language · Computer Science 2025-03-04 Zaifu Zhan , Shuang Zhou , Huixue Zhou , Jiawen Deng , Yu Hou , Jeremy Yeung , Rui Zhang

Language models pre-trained on biomedical corpora, such as BioBERT, have recently shown promising results on downstream biomedical tasks. Many existing pre-trained models, on the other hand, are resource-intensive and computationally heavy…

Computation and Language · Computer Science 2022-09-08 Omid Rohanian , Mohammadmahdi Nouriborji , Samaneh Kouchaki , David A. Clifton

Despite their strong linguistic capabilities, Large Language Models (LLMs) are computationally demanding and require substantial resources for fine-tuning, which is unadapted to privacy and budget constraints of many healthcare settings. To…

Computation and Language · Computer Science 2026-04-30 Pierre Epron , Adrien Coulet , Mehwish Alam

Developing high-performance entity normalization algorithms that can alleviate the term variation problem is of great interest to the biomedical community. Although deep learning-based methods have been successfully applied to biomedical…

Information Retrieval · Computer Science 2019-08-12 Zongcheng Ji , Qiang Wei , Hua Xu

We present a statistical model for German medical natural language processing trained for named entity recognition (NER) as an open, publicly available model. The work serves as a refined successor to our first GERNERMED model which is…

Computation and Language · Computer Science 2022-10-11 Johann Frei , Ludwig Frei-Stuber , Frank Kramer

Recent advancements in language models (LMs) have led to the emergence of powerful models such as Small LMs (e.g., T5) and Large LMs (e.g., GPT-4). These models have demonstrated exceptional capabilities across a wide range of tasks, such…

Computation and Language · Computer Science 2024-05-07 Mingchen Li , Rui Zhang

Named Entity Recognition (NER) is essential in various Natural Language Processing (NLP) applications. Traditional NER models are effective but limited to a set of predefined entity types. In contrast, Large Language Models (LLMs) can…

Computation and Language · Computer Science 2023-11-16 Urchade Zaratiana , Nadi Tomeh , Pierre Holat , Thierry Charnois

We evaluate four state-of-the-art instruction-tuned large language models (LLMs) -- ChatGPT, Flan-T5 UL2, Tk-Instruct, and Alpaca -- on a set of 13 real-world clinical and biomedical natural language processing (NLP) tasks in English, such…

Computation and Language · Computer Science 2024-06-11 Yanis Labrak , Mickael Rouvier , Richard Dufour

Recognition of biomedical entities from literature is a challenging research focus, which is the foundation for extracting a large amount of biomedical knowledge existing in unstructured texts into structured formats. Using the sequence…

Computation and Language · Computer Science 2021-05-18 Cong Sun , Zhihao Yang , Lei Wang , Yin Zhang , Hongfei Lin , Jian Wang

This study proposes a medical entity extraction method based on Transformer to enhance the information extraction capability of medical literature. Considering the professionalism and complexity of medical texts, we compare the performance…

Computation and Language · Computer Science 2025-04-08 Xiaokai Wang , Guiran Liu , Binrong Zhu , Jacky He , Hongye Zheng , Hanlu Zhang

We study clinical Named Entity Recognition (NER) on the CADEC corpus and compare three families of approaches: (i) BERT-style encoders (BERT Base, BioClinicalBERT, RoBERTa-large), (ii) GPT-4o used with few-shot in-context learning (ICL)…

Computation and Language · Computer Science 2025-10-28 Andrei Baroian

Pre-trained language models induce dense entity representations that offer strong performance on entity-centric NLP tasks, but such representations are not immediately interpretable. This can be a barrier to model uptake in important…

Computation and Language · Computer Science 2021-06-18 Diego Garcia-Olano , Yasumasa Onoe , Ioana Baldini , Joydeep Ghosh , Byron C. Wallace , Kush R. Varshney

In this research, we explored the improvement in terms of multi-class disease classification via pre-trained language models over Medical-Abstracts-TC-Corpus that spans five medical conditions. We excluded non-cancer conditions and examined…

Computation and Language · Computer Science 2024-11-20 Ahmed Akib Jawad Karim , Muhammad Zawad Mahmud , Samiha Islam , Aznur Azam

Pretrained language models such as Bidirectional Encoder Representations from Transformers (BERT) have achieved state-of-the-art performance in natural language processing (NLP) tasks. Recently, BERT has been adapted to the biomedical…

Computation and Language · Computer Science 2023-02-06 Li Fang , Qingyu Chen , Chih-Hsuan Wei , Zhiyong Lu , Kai Wang

Motivation: State-of-the-art biomedical named entity recognition (BioNER) systems often require handcrafted features specific to each entity type, such as genes, chemicals and diseases. Although recent studies explored using neural network…

Information Retrieval · Computer Science 2018-10-09 Xuan Wang , Yu Zhang , Xiang Ren , Yuhao Zhang , Marinka Zitnik , Jingbo Shang , Curtis Langlotz , Jiawei Han

Natural language processing (NLP) of clinical trial documents can be useful in new trial design. Here we identify entity types relevant to clinical trial design and propose a framework called CT-BERT for information extraction from clinical…

Quantitative Methods · Quantitative Biology 2021-10-20 Xiong Liu , Greg L. Hersch , Iya Khalil , Murthy Devarakonda