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Physically motivated stochastic dynamics are often used to sample from high-dimensional distributions. However such dynamics often get stuck in specific regions of their state space and mix very slowly to the desired stationary state. This…

Machine Learning · Statistics 2025-05-13 Abhijith Jayakumar , Andrey Y. Lokhov , Sidhant Misra , Marc Vuffray

Stochasticity can play an important role in the dynamics of biologically relevant populations. These span a broad range of scales: from intra-cellular populations of molecules to population of cells and then to groups of plants, animals and…

Statistical Mechanics · Physics 2017-07-04 Michael Assaf , Baruch Meerson

When clustering molecular dynamics (MD) trajectories into a few metastable conformational states, the Markov state models (MSMs) assumption of timescale separation between fast intrastate fluctuations and rarely occurring interstate…

Soft Condensed Matter · Physics 2025-01-17 Sofia Sartore , Franziska Teichmann , Gerhard Stock

We provide results of a deterministic approximation for non-Markovian stochastic processes modeling finite populations of individuals who recurrently play symmetric finite games and imitate each other according to payoffs. We show that a…

Dynamical Systems · Mathematics 2023-06-05 Ozgur Aydogmus , Yun Kang

Motivated by the study of a parasite infection in a cell line, we introduce a general class of Markov processes for the modelling of population dynamics. The population process evolves as a diffusion with positive jumps whose rate is a…

Probability · Mathematics 2021-06-01 Aline Marguet , Charline Smadi

We analyse the dynamics of metastable Markovian open quantum systems by unravelling their average dynamics into stochastic trajectories. We use quantum reset processes as examples to illustrate metastable phenomenology, including a simple…

Quantum Physics · Physics 2024-04-08 Calum A. Brown , Katarzyna Macieszczak , Robert L. Jack

We consider continuous time Markovian processes where populations of individual agents interact stochastically according to kinetic rules. Despite the increasing prominence of such models in fields ranging from biology to smart cities,…

Machine Learning · Statistics 2016-05-16 Anastasis Georgoulas , Jane Hillston , Guido Sanguinetti

Stochastic processes that are randomly reset to an initial condition serve as a showcase to investigate non-equilibrium steady states. However, all existing results have been restricted to the special case of memoryless resetting protocols.…

Statistical Mechanics · Physics 2016-03-23 Stephan Eule , Jakob Metzger

Neuronal networks can generate burst events. It remains unclear how to analyse interburst periods and their statistics. We study here the phase-space of a mean-field model, based on synaptic short-term changes, that exhibit burst and…

Statistical Mechanics · Physics 2020-12-17 Lou Zonca , David Holcman

Simulation methods based on stochastic realizations of state vector evolutions are commonly used tools to solve open quantum system dynamics, both in the Markovian and non-Markovian regime. Here, we address the question of waiting time…

Quantum Physics · Physics 2012-09-10 Kimmo Luoma , Kari Härkönen , Sabrina Maniscalco , Kalle-Antti Suominen , Jyrki Piilo

Stochastic models of biochemical reaction networks are widely used to capture intrinsic noise in cellular systems. The typical formulation of these models are based on Markov processes for which there is extensive research on efficient…

Molecular Networks · Quantitative Biology 2025-12-03 Thomas P. Steele , David J. Warne

This study introduces a comparative modeling framework using stationary and non-stationary transition probabilities within a Markov Decision Process (MDP) to assess COVID-19 disease dynamics. Stationary transition probabilities assume…

In this paper, we propose a stochastic cellular automaton model of traffic flow extending two exactly solvable stochastic models, i.e., the asymmetric simple exclusion process and the zero range process. Moreover it is regarded as a…

Statistical Mechanics · Physics 2009-05-26 Masahiro Kanai , Katsuhiro Nishinari , Tetsuji Tokihiro

Recently, a first step was made by the authors towards a systematic investigation of the effect of reaction-step-size noise - uncertainty in the step size of the reaction - on the dynamics of stochastic populations. This was done by…

Statistical Mechanics · Physics 2016-12-21 Shay Be'er , Michael Assaf

We study classical stochastic systems with discrete states, coupled to switching external environments. For fast environmental processes we derive reduced dynamics for the system itself, focusing on corrections to the adiabatic limit of…

Statistical Mechanics · Physics 2019-03-27 Peter G. Hufton , Yen Ting Lin , Tobias Galla

Quasistationary states are long-lived nonequilibrium states, observed in some systems with long-range interactions under deterministic Hamiltonian evolution. These intriguing non-Boltzmann states relax to equilibrium over times which…

Statistical Mechanics · Physics 2015-03-17 Shamik Gupta , David Mukamel

We study random transitions between two metastable states that appear below a critical temperature in a one dimensional self-gravitating Brownian gas with a modified Poisson equation experiencing a second order phase transition from a…

Statistical Mechanics · Physics 2014-04-23 P. H. Chavanis , L. Delfini

We are interested in the connection between a metastable continuous state space Markov process (satisfying e.g. the Langevin or overdamped Langevin equation) and a jump Markov process in a discrete state space. More precisely, we use the…

Probability · Mathematics 2017-02-08 Giacomo Di Gesù , Tony Lelièvre , Dorian Le Peutrec , Boris Nectoux

Local networks of neurons are nonlinear systems driven by synaptic currents elicited by its own spiking activity and the input received from other brain areas. Synaptic currents are well approximated by correlated Gaussian noise. Besides,…

Neurons and Cognition · Quantitative Biology 2024-04-09 Gianni Valerio Vinci , Maurizio Mattia

We develop a stochastic framework for viral population dynamics at the cellular level that explicitly incorporates the replication cycle with random stage durations. The model is formulated as a structured birth-death process coupled with a…

Populations and Evolution · Quantitative Biology 2026-05-13 Seong Jun Park