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Quantum Computing allows, in principle, the encoding of the exponentially scaling many-electron wave function onto a linearly scaling qubit register, offering a promising solution to overcome the limitations of traditional quantum chemistry…

Quantum Physics · Physics 2025-10-21 C. Feniou , O. Adjoua , B. Claudon , J. Zylberman , E. Giner , J. -P. Piquemal

We propose Scalable Quantum Molecular Generation (SQMG), a variational quantum-circuit for sampling molecular graphs using chemical priors on atoms and bonds. SQMG assigns a fixed 3-qubit register to each heavy atom and reuses a single…

Nuclear magnetic resonance spectroscopy is one of the few remaining areas of physical chemistry for which polynomially scaling simulation methods have not so far been available. Here, we report such a method and illustrate its performance…

Chemical Physics · Physics 2014-07-16 Luke J. Edwards , D. V. Savostyanov , Z. T. Welderufael , Donghan Lee , Ilya Kuprov

Quantum state tomography (QST) is essential for validating quantum devices but suffers from exponential scaling in system size. Neural-network quantum states, such as Restricted Boltzmann Machines (RBMs), can efficiently parameterize…

Quantum Physics · Physics 2026-01-30 Simon Tonner , Viet T. Tran , Richard Kueng

Quantum computing methods for excited-state calculations remain underexplored in Noisy Intermediate-Scale Quantum (NISQ) hardware, despite their critical role in photochemistry and material science. Herein, we propose a resource-efficient…

Quantum Physics · Physics 2025-06-16 Qianjun Yao , He Li

In the near future, material and drug design may be aided by quantum computer assisted simulations. These have the potential to target chemical systems intractable by the most powerful classical computers. However, the resources offered by…

Quantum computing holds immense promise for simulating quantum systems, a critical task for advancing our understanding of complex quantum phenomena. One of the primary goals in this domain is to accurately approximate the ground state of…

Quantum Physics · Physics 2024-11-28 Thilo R. Müller , Manuel Geiger , Christian B. Mendl

Quantum machine learning algorithms have emerged to be a promising alternative to their classical counterparts as they leverage the power of quantum computers. Such algorithms have been developed to solve problems like electronic structure…

Chemical Physics · Physics 2021-10-29 Manas Sajjan , Shree Hari Sureshbabu , Sabre Kais

Some of the computational limitations in solving the nuclear many-body problem could be overcome by utilizing quantum computers. The nuclear shell-model calculations providing deeper insights into the properties of atomic nuclei, is one…

Quantum Physics · Physics 2026-05-25 Nifeeya Singh , Pooja Siwach , P. Arumugam

In recent years, researchers have been exploring the applications of noisy intermediate-scale quantum (NISQ) computation in various fields. One important area in which quantum computation can outperform classical computers is the ground…

Quantum Physics · Physics 2024-01-30 Ruyu Yang , Tianren Wang , Bing-Nan Lu , Ying Li , Xiaosi Xu

A new basis adaptive algorithm for hybrid quantum-classical platforms is introduced to efficiently find the ground-state (gs) properties of quantum many-body systems. The method addresses limitations of many algorithms, such as Variational…

Strongly Correlated Electrons · Physics 2025-12-16 Anutosh Biswas , Sayan Ghosh , Ritajit Majumdar , Mostafizur Rahaman , Manoranjan Kumar

The Research & Development (R&D) phase of drug development is a lengthy and costly process. To revolutionize this process, we introduce our new concept QMLS to shorten the whole R&D phase to three to six months and decrease the cost to…

Biomolecules · Quantitative Biology 2024-09-06 Yifan Zhou , Yan Shing Liang , Yew Kee Wong , Haichuan Qiu , Yu Xi Wu , Bin He

We present a quantum-classical hybrid random power method that approximates a ground state of a Hamiltonian. The quantum part of our method computes a fixed number of elements of a Hamiltonian-matrix polynomial via quantum polynomial…

Quantum Physics · Physics 2025-04-17 Taehee Ko , Hyowon Park , Sangkook Choi

Advances in quantum simulator technology is increasingly required because research on quantum algorithms is becoming more sophisticated and complex. State vector simulation utilizes CPU and memory resources in computing nodes exponentially…

Quantum Physics · Physics 2024-09-04 Mikio Morita , Yoshinori Tomita , Junpei Koyama , Koichi Kimura

Quantum error mitigation (QEM) has emerged as a powerful tool for the extraction of useful quantum information from quantum devices. Here, we introduce the Subspace Noise Tailoring (SNT) algorithm, which efficiently combines the cheap cost…

Classical simulation of quantum computation has often been viewed as the method to determine where the horizon of quantum supremacy is located---that is, where quantum computation can no longer be simulated by classical methods. As of now,…

Quantum Physics · Physics 2017-11-21 Andrew Shi

Quantum state tomography (QST), the process of reconstructing some unknown quantum state $\hat\rho$ from repeated measurements on copies of said state, is a foundationally important task in the context of quantum computation and simulation.…

Quantum Physics · Physics 2025-10-21 Nathan Keenan , John Goold , Alex Nico-Katz

Under suitable assumptions, the algorithms in [Lin, Tong, Quantum 2020] can estimate the ground state energy and prepare the ground state of a quantum Hamiltonian with near-optimal query complexities. However, this is based on a block…

Quantum Physics · Physics 2022-10-19 Yulong Dong , Lin Lin , Yu Tong

The Helstrom measurement (HM) is known to be the optimal strategy for distinguishing non-orthogonal quantum states with minimum error. Previously, a binary classifier based on classical simulation of the HM has been proposed. It was…

Quantum Physics · Physics 2024-03-25 Wooseop Hwang , Daniel K. Park , Israel F. Araujo , Carsten Blank

Quantum computer simulators are an indispensable tool for prototyping quantum algorithms and verifying the functioning of existing quantum computer hardware. The current largest quantum computers feature more than one thousand qubits,…

Quantum Physics · Physics 2025-01-28 Gabin Schieffer , Stefano Markidis , Ivy Peng